The invention discloses a hand-held small-sized 3D printer which comprises a base, a printing platform and a lifting bracket, wherein the Z-axis lifting motor and a lifting guide rail are arranged at the top of the base; the Z-axis lifting motor is connected with a lifting screw, the lifting guide rail and the lifting screw both penetrate through the lifting bracket, a handle is arranged at the top of the lifting guide rail, the lifting bracket is connected with a first horizontal support rod, a second horizontal support rod, a mobile plate, an X-axis mobile motor, a horizontal support plate and a first annular gear driving belt, one edge of the first annular gear driving belt penetrates through the mobile plate, and the mobile plate is provided with a vertically arranged printing head; the printing platform comprises a bottom plate; and the bottom plate is connected with a first polished rod, a second polished rod, the printing platform, a Y-axis mobile motor and a second annular gear driving belt, and the upper edge of the second annular gear driving belt is arranged in the printing platform in an embedded manner. The hand-held small-sized 3D printer disclosed by the invention has the advantages of compact structure, small size, portability, convenience for carrying and high accuracy of Z-axis direction lifting and X-axis direction motion of the printing head.