The invention discloses a high-efficiency grain flotation dedusting and sand removal device, which comprises a feed pipe, a flow meter, a water inlet pipe, a screening box, a vibrating sieve plate, a runner, a rotating shaft, a liquid level gauge, an impeller, a sundry discharge pipe, Grain discharge pipe and drying box, the feed pipe is connected with the screening box, the feeding pipe is provided with an inclined filter, the water inlet pipe is connected with the upper part of the screening box, the water inlet pipe is provided with a flow meter, and the screening box is provided with a liquid filter. Position gauge, a transparent glass plate is installed on the side wall of the screening box, a rotating shaft is installed in the screening box, an impeller is installed at the bottom of the rotating shaft, a vibrating sieve plate is installed in the screening box, and the two ends of the vibrating sieve plate are connected to the outer edge of the runner through the connecting piece. Connection, one side of the screening box is provided with a debris discharge pipe and a grain discharge pipe from top to bottom, and one end of the grain discharge pipe is connected with the drying box. The invention prevents the air from being covered with dust, ensures the health of farmers, makes sand and gravel sink to the bottom due to buoyancy, ensures the quality of products, has a simple structure, is convenient to use, and is beneficial to popularization.