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49results about How to "Minimize the risk of damage" patented technology

Solution formulations of sirolimus and its analogs for CAD treatment

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Owner:WYETH LLC

Intraocular lens inserter

An intraocular lens is laterally compressed prior to insertion through an eye incision using an inserter adapted to minimize damage to the intraocular lens. The inserter includes a handpiece with a longitudinal bore, a cartridge holder at the distal end of the handpiece bore, and a discharge nozzle with a tapered bore on the distal side of the cartridge holder. A prepackaged cartridge holding an intraocular lens is mounted in the cartridge holder. The intraocular lens has an optic with leading and trailing haptics axially aligned with the handpiece and nozzle bores. A plunger compresses the lens by moving the lens through the nozzle tapered bore. One plunger described includes flexible distal arms that compress inwardly to maintain the arm tips against the sides of the optic, while another plunger includes an angular tip that engages a hole in the leading haptic to pull the lens through the tapered bore.
Owner:STRATAS BYRON A

Local administration of a combination of rapamycin and cilostazol for the treatment of vascular disease

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. The drugs, agents, and/or compounds may also be utilized to treat specific diseases, including vulnerable plaque. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Owner:WYETH LLC

Local vascular delivery of PI3 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Owner:WYETH LLC

Mobile Washer Unit

A mobile pressure washing system is provided. The system comprises a frame with hinged elements for transitioning the frame between an upright position of use and a compact position for secure transport and storage of the system. System features further include a removable and replaceable tank adapted to fit on a portion of the frame, storage features, and pressure washing features such as a motor and pump.
Owner:KARCHER NORTH AMERICA INC

Frozen soil layer natural gas hydrate horizontal branch well pattern mining system and method

InactiveCN109736769AReasonable designImprove production efficiency and economic benefitsFluid removalDirectional drillingDecompositionPlacer mining
The invention discloses a frozen soil layer natural gas hydrate horizontal branch well pattern mining system and method. The system comprises a main drilling well, a production area, a production well, an area multi-branch well, a production area boundary, a filling body, a decomposition enhancement area, a main drilling well horizontal section, a main drilling well vertical section, a branch well, a decomposition circle and an arch structure. The multi-branch well pattern has the beneficial effects that the multi-branch well pattern can improve the pressure sensitivity of formation fluid andprovide more decomposition free surfaces for natural gas hydrates; after mining is finished, grouting operation is carried out to fill cavities and through cracks formed after mining, the rock stratumarch structure is enhanced, potential environment damage risks are reduced, and the division of production areas and the succession order between the production areas in the long-term production process are planned.
Owner:CHINA UNIV OF MINING & TECH

Method for producing a tapered roller assembly, tapered roller assembly and tapered roller bearing

Tapered roller bearings have in many design forms an inner ring, an outer ring and a plurality of tapered rollers which are arranged to roll between the inner ring and outer ring. It is the object ofthe present invention to propose a method for producing a tapered roller assembly which can be mounted in a particularly simple manner. For this purpose, a method for producing a tapered roller assembly (1) having an inner ring (3) and a roller ring (12) is proposed, wherein the method comprises the following steps: a) providing the inner ring (3), wherein the inner ring (3) has a flanged mountingrim (10) which is produced within a preliminary flanging stage by flanging over an edge region (6) of the inner ring (3); b) mounting the roller ring (12) on the inner ring (3), wherein the roller ring (12) is pushed over the flanged mounting rim (10) onto the inner ring (3); c) flanging over the flanged mounting rim (10) into a flanged rim (15), wherein the flanged rim (15), as a retaining rim,captively retains the roller ring (12); and d) heat-treating the flanged mounting rim (10) before step b) or step c), wherein a hardness of the flanged mounting rim (10) is reduced by comparison witha hardness of a raceway (5) of the inner ring (3). Also proposed is a tapered roller bearing (20) formed with such a tapered roller assembly (1).
Owner:SCHAEFFLER TECH AG & CO KG
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