174results about How to "Minimize risk" patented technology

Methods and systems for minimally invasive replacement of a valve. The system includes a collapsible valve and anchoring structure, devices and methods for expanding the valve anchoring structure, adhesive means to seal the valve to the surrounding tissue, a catheter-based valve sizing and delivery system, native valve removal means, and a temporary valve and filter assembly to facilitate removal of debris material. The valve assembly comprises a valve and anchoring structure for the valve, dimensioned to fit substantially within the valve sinus.

A method and apparatus for delivering a device to a given location within a heart, the method and apparatus being adapted for: passing a first catheter through the left atrium of the heart, through the mitral valve and into the left ventrical, and passing a second catheter through the aorta toward the heart, one or the other of the first catheter and the second catheter, with the device attached thereo, forming a device-carrying assembly for engagement with the remaining catheter; causing the device-carrying assembly and the remaining catheter to engage one another so as to form a connection therebetween; and retracting one of the device-carrying assembly and the remaining catheter in a direction opposite to the other of the device-carrying assembly and the remaining catheter so as to position the device relative to the given location within the heart.

Embodiments of the present invention can be directed to systems, apparatuses, and methods for performing transactions through mobile communication devices using telecommunications networks, systems, or proximity near-field communications systems. Embodiments may be directed to a mobile communication device displaying an application authentication element including a pre-selected authentication element. The application authentication element may include transaction data associated with a transaction conducted by a mobile communication device. The mobile communication device may obtain the pre-selected authentication element by either transmitting a request to a server computer or retrieving the pre-selected authentication element from a secure memory in the mobile communication device. A user authentication token may then be received by the mobile communication device from the user. The mobile communication device may then generate a secret token derived from the user authentication token, and if the secret token is correlated to a secret reference token, a transaction may be conducted.

Methods and systems for minimally invasive replacement of a valve. The system includes a collapsible valve and anchoring structure, devices and methods for expanding the valve anchoring structure, adhesive means to seal the valve to the surrounding tissue, a catheter-based valve sizing and delivery system, native valve removal means, and a temporary valve and filter assembly to facilitate removal of debris material. The valve assembly comprises a valve and anchoring structure for the valve, dimensioned to fit substantially within the valve sinus.

Methods and systems for minimally invasive replacement of a valve. The system includes a collapsible valve and anchoring structure, devices and methods for expanding the valve anchoring structure, adhesive means to seal the valve to the surrounding tissue, a catheter-based valve sizing and delivery system, native valve removal means, and a temporary valve and filter assembly to facilitate removal of debris material. The valve assembly comprises a valve and anchoring structure for the valve, dimensioned to fit substantially within the valve sinus.

A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes first and second tubular members having proximal ports, distal ports, and lumens therebetween. The distal port of the second tubular member is adapted for releasable attachment to the proximal port of the first tubular member. A second lumen merges and communicates at its distal end with the lumen of the first tubular member and includes a hemostatic valve attached to its proximal end. In using the apparatus for performing open endarterectomy, a filter device is inserted into the vessel and deployed downstream the region of interest in the internal carotid artery. The distal end of the shunt is advanced over the filter device and secured onto the artery. The proximal end of the shunt is inserted upstream the region of interest, typically in the common carotid artery.

Methods and devices are provided for intervertebral implant anchorage. An implantable device for insertion into an intradiscal section between adjacent vertebrae is provided. The implantable device includes at least one anchor plate which comprises a plate member sized to be positioned within an intradiscal section between adjacent vertebrae and a plurality of anchoring elements extending from a surface of the plate member, each anchoring element including a distal—portion capable of being introduced into the vertebra through the vertebral end plate; and an intradiscal component coupled to the anchor plate.

A carbon credit is a generic term for any tradable certificate or permit representing the right to emit one ton of carbon dioxide or the mass of another greenhouse gas with a carbon dioxide equivalent (tCO2e) equivalent to one ton of carbon dioxide.Carbon credits and carbon markets are a component of national and international attempts to mitigate the growth in concentrations of greenhouse gases (GHGs). One carbon credit is equal to one ton of carbon dioxide, or in some markets, carbon dioxide equivalent gases. Carbon trading is an application of an emissions trading approach. Greenhouse gas emissions are capped and then markets are used to allocate the emissions among the group of regulated sources.Carbon credits can be generated by any process that conforms to ISO 14064-66 standards. Once generated, carbon credits can be stored in a distributed, Cloud-based ledger. The ledger entries can serve as a registry for carbon credits as well as the data source for an Internet-enabled trading system or financial exchange that allows the carbon credits to be sold and bought as part of the same system. The distributed ledger can provide records that combine the details of the carbon credits' origin, transaction history, and financial instructions associated with trading of the carbon credits via a distributed ledger system.

Systems and methods for analyzing the service and performance levels associated with virtual machines in a storage network environment for compliance with a resource capacity policy are provided. Component configuration and connectivity information from components in the network environment is collected without using host agents on the virtual machines. Access paths defining end-to-end access relationships between an application on a virtual machine and storage data objects associated with the virtual machine in the network environment are derived. Access paths comprise sequences of components configured to enable information flow between an application residing on a virtual machine and a data object on a respective storage device. Access path resource consumption is computed and virtual machines with resource consumptions that violate the resource capacity policy are identified.

A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from the kidney. The device can be a drug pump or a drug eluding implant for targeted delivery of a nerve-blocking agent to the periarterial space of the renal artery.

A safety needle includes a needle with a sharp end and a needle shield. The needle shield includes collapsible interlocking members, wherein one member is an end member with a hole surrounding the needle, a spring inside the collapsible interlocking members that applies an expanding force on the collapsible interlocking members, a releasable latch structure that retains the collapsible interlocking members in a collapsed state, wherein when the releasable latch structure is actuated the collapsible interlocking members expand and enclose the sharp end of the needle, and a closing structure that prevents the sharp end of the needle from exiting the hole after the collapsible interlocking members enclose the sharp end of the needle.

A torque device for selectively gripping a medical guidewire. The device includes a housing, an actuator slidably mounted on the housing, and a resilient member biasing the actuator. A lumen dimensioned to receive the guidewire extends through the housing and actuator. The resilient member biases the actuator from a first position in which the lumen portions are aligned, toward a second position in which the lumen portions are misaligned. The actuator may include a catch that interferes with a stop of the housing to retain the actuator within the housing. The actuator may be oblong or otherwise shaped to maintain the lumen portions in substantial alignment in a longitudinal direction. Preferably, at least a portion of the lumen is teardrop-shaped in cross-section. The housing may include circumferentially or longitudinally extending ribs defining an outer grasping surface. Frusto-conical cavities may be defined at entry and exit ends of the lumen.

A system and automated method for verification of employment history regarding a job applicant, the method including receiving information identifying an applicant, receiving employment history information for the job applicant, receiving information identifying an identified verification contact for verification of the employment history information, automatically providing the identified verification contact with a question pertaining to employment history information, receiving an answer from the identified verification contact, storing the answer.

The invention relates to an imprint apparatus for carrying out a two-step process for transferring a pattern from a template (1) to a target surface of a substrate. The apparatus works by creating an intermediate disc, e.g. from a flexible polymer stamp (10), by imprint from the template in a first imprint unit (200). A feeder device 410 is then operated to feed the intermediate stamp to a second imprint unit (300), where it is used to make an imprint in a target surface of a substrate.

A device and related method for the removal of subcutaneous adipose layers comprises a laser source; an optical fiber for conveying a laser beam emitted by the laser source; and a hollow cannula for guiding the fiber to the subcutaneous treatment area. The cannula has a curved portion at its distal end, where the curved portion can be shaped to roughly conform to the contour of the patient's body structure. In this way, laser energy from the fiber, applied to the adipose layers, is generally directed away from the lower dermis of the patient, minimizing the risk of non-reversible damage to the dermis, including skin necrosis. In another embodiment, the optical fiber is a side-firing fiber that directs the laser energy away from the dermis. In other embodiments, a radiation detector, such as a thermal or optical sensor, monitors the temperature at the surface of the skin above the treatment area to warn the operator of harmful temperatures in the lower dermis. In another embodiment, a temperature sensitive material is applied to the surface of the skin above the treatment area to warn of harmful dermal temperatures. In another embodiment, a cooling mechanism cools the surface of the skin above the treatment area to prevent damage to the dermis.

A system for heat ablation of tissue in a patient comprises a plurality of electrodes operatively connected to a source of radiofrequency energy and configured to apply RF energy to tissue at a patient site, a plurality of RF current restricting circuits, each circuit coupled between one of the plurality of electrodes and the source of radiofrequency energy, and configured to restrict RF energy to the electrode when the current restricting circuit is enabled and not restrict RF energy to flow to the electrode when the current restricting circuit is disabled, at least one return electrode adapted to contact the patient and configured to return RF energy to the RF source; and a switching mechanism configured to selectively enable each of the plurality of RF current restricting circuits, in one of a sequential and non sequential fashion, wherein the switching mechanism is isolated from each of the current restricting circuits.

The present invention relates to methods and compositions for the cryopreservation of pluripotent cells in general and human embryonic stem (ES) cells in particular. The stem cells are grown on a bottom layer of solid support matrix and subsequently covered by a top layer of solid support matrix forming a matrix-cell-matrix composition, to which an effective amount of cryopreservation media is added, prior to freezing. The methods of the invention yield cryopreserved cells that exhibit an increase in cell viability and a decrease in cell differentiation, facilitating storage, shipping and handling of embryonic stem cell stocks and lines for research and therapeutics.

Method and set of surgical instruments for fitting a shoulder prosthesis, and the shoulder prosthesis. The proposed method seeks to interpose a bone graft between the previously prepared glenoid surface (G) of a scapula (S) of a patient's shoulder and the face of a glenoid prosthetic component opposite the articular surface. The set of instruments permit the bone graft to be taken from the upper epiphysis of the humerus (H), either in situ or ex vivo.

Devices, systems and methods are disclosed which relate to optimizing a minimum cost function associated with buried asset lines by using a GIS application to generate a “dynamic buffer” around each asset line based on a risk management algorithm. A risk management algorithm, by which a GIS application can generate a “dynamic buffer”, is employed to minimize asset line damage risk and operating costs by balancing potential costs from damage against the fixed labor costs of manually screened and located tickets. Embodiments of the invention utilize the geography of the situation as well as factors for the asset itself.

Devices and methods are disclosed for protecting individuals from the sharp ends of medical objects following use on a patient. Such sharp objects include hypodermic needles, scalpel blades, cannulae, trocars, and the like. The invention utilizes a disposable protective cover for the used sharp. The protective cover is designed to surround and embed the sharp in a permanent cover that is blunt and will not permit further puncture or cutting with the sharp. In an embodiment, the protective cover also absorbs any fluids on or in the used sharp and prevents any fluids from escaping the protective cover. The sharp cover is configured to irreversibly lock, once closed. A refillable or replaceable dispenser dispenses the protective covers at points of use. A disposable receptacle receives the used sharp embedded in the protective cover. When the receptacle is full, the entire receptacle may be discarded in a medical waste container.

The device and method for remotely monitoring animal behavior consists of a sensor unit mounted on an animal. The sensor unit utilizes motion sensors to monitor the specific behavioral patterns of the animal. Power management is controlled to turn the system on when specific types of motion are detected. Motion data is wirelessly transmitted to a base station for analysis. Data analysis functions are used to detect and identify the occurrence of characteristic motions. Network decision algorithms analyze the characteristic motions and compute weighted indicators and weighted counter-indicators which are combined into a final diagnostic score. When the final diagnostic score exceeds a threshold value, a specific behavioral pattern is confirmed which may indicate the animal is in a distress situation or experiencing another type of behavior that requires intervention. If distress is detected, the system sends a communication to notify the appropriate personnel that a distress condition exists.

An ATM includes a user interface having plural electronic ink displays. Displays can be used as identification labels. A display identifying the function of a transaction function device can be located adjacent to that device. Displays can also be used to provide instructions to machine users. A display on how to insert a card into the ATM can be located adjacent the card input slot. An display can be in direct communication with both a card reader and an encryption pin pad (“EPP”). Upon suspecting card reader tampering, the card reader can instruct the display to present a message warning of the situation. Likewise, upon suspecting EPP tampering, the EPP can instruct the display to present a warning message. Displays can also instruct a machine user on when and when not to insert their PIN depending on the mode of the EPP.

An automated system (100) and method for optimizing project risk and return from the perspective of the sponsor. The project, project features and feature options are defined using project design system and project financial system data. The expected project outputs are then mapped to matrices of value and risk for the sponsor. The system calculates a value for the project then identifies the mix of features and feature options that maximize expected project value from the perspective of the sponsor. The system also identifies the mix of features and feature options that maximize expected project value while minimizing project risk from other frames.

The invention provides a method of trimming a structure that includes a first wafer bonded to a second wafer, with the first wafer having a chamfered edge. The method includes a first trimming step carried out over a first depth that includes at least the thickness of the first wafer and over a first width determined from the edge of the first wafer. A second trimming step is then carried out over a second depth that includes at least the thickness of the first wafer and over a second width that is less than the first width.

Disclosed are compositions and methods for preventing, inhibiting, reducing and treating conditions and diseases associated with abnormal bone resorption in mammals, including for example osteoporosis. Embodiments of compositions of the invention comprise a pharmaceutically effective amount of alendronate and vitamin D3 suitable for once-weekly dosing. Compositions and methods of the invention provide vitamin D nutrition during bisphosphonate treatment to facilitate normal bone formation and mineralization while minimizing the occurrence of or potential for the complications associated with vitamin D insufficiency, such as hypocalcaemia and osteomalacia. Also disclosed are methods for manufacturing compositions of the present invention, for measuring stability and degradation of those compositions, and for measuring blood plasma levels of vitamin D.

In accordance with the principles of the present invention, a standardized contract is traded. The contract obligates a buyer and a seller to settle the contract based on a price determined for an effective date. The contract is traded over-the-counter or through an exchange and cleared by a clearinghouse that guarantees payment to the buyer of any amount owed to the buyer from the seller as a result of the contract and that guarantees payment to the seller of any amount owed to the seller from the buyer as a result of the contract. An over-the-counter or exchange traded instrument is utilized to determine the rate that is used to determine the price of the contract.