90results about How to "Loss of production" patented technology

A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical / non-medical objects. It can be used to prepare single or multiple articles.

The present invention relates generally to methods, compositions and kits for synthesizing sense RNA molecules from one or more RNA molecules of interest in a sample. In exemplary embodiments, the methods use a terminal tagging oligoribonucleotide (rTTO) to join a DNA sequence tag to the 3′-termini of first-strand cDNA molecules. The use of an rTTO comprising ribonucleotides results in decreased oligonucleotide-derived background synthesis of RNA in the absence of sample RNA and, surprisingly and unexpectedly, also results in significantly increased yields of sense RNA molecules that exhibit sequences that are substantially identical to those of the RNA molecules of interest in the sample. The sense RNA molecules also have an RNA sequence tag on their 5′-termini that is useful for fixing the lengths of sense RNA molecules that are synthesized in a second or subsequent round.

A leak detection system for the detection and monitoring of pressurized refrigerant systems, primarily walk-in refrigeration units in stores or storage facilities, manages, monitors and controls the refrigeration system which store and preserve perishables. The system includes a gas refrigerant detector and a monitor and relay system to alert the store personnel and remote monitoring stations that a problem exists by detecting the presence of gas outside the system within the refrigeration units, assessing the magnitude of the problem, and providing an emergency shutoff means to close and contain the refrigeration system contents in the event a substantial refrigeration leak is detected, closing the system until system repairs are made and the system is reset.

An extrusion process for manufacturing thermosetting powder coating compositions is disclosed. A base material is fed to an extruder body such as from a pre-mix hopper; in one embodiment, hard to incorporate additives, such as pigments, are added to the base material after they exit from the pre-mix hopper and before they exit from the extruder body. In another embodiment, hard to incorporate additives in a dried form are added with the base material. The combined base material and hard to incorporate additives are mixed through at least a portion of the extruder body to form a homogeneous thermosetting powder coating composition. The output of the extruder body may be monitored for composition accuracy, wherein the amount of hard to incorporate additives added is dynamically adjusted based upon the monitored output. The process may be repeated for thermosetting powder coating compositions having distinct hard to incorporate additives utilizing a common base material in the pre-mix hopper. Use of one or more hyperdispersed pigments in the formation of a powder coating is also disclosed.

Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed ("SMB") system and a SMB apparatus for use in these methods. Also provided are purified immunoreactive compounds prepared using the SMB methods and apparatus and methods of treatment with the purified immunoreactive compounds.

A new polymerization process (atom transfer radical polymerization, or ATRP) based on a redox reaction between a transition metal (e.g., Cu(I) / Cu(II), provides “living” or controlled radical polymerization of styrene, (meth)acrylates, and other radically polymerizable monomers. Using various simple organic halides as model halogen atom transfer precursors (initiators) and transition metal complexes as a model halogen atom transfer promoters (catalysts), a “living” radical polymerization affords (co)polymers having the predetermined number average molecular weight by Δ[M] / [I]0 (up to Mn>105) and a surprisingly narrow molecular weight distribution (Mw / Mn), as low as 1.15. The participation of free radical intermediates in ATRP is supported by end-group analysis and stereochemistry of the polymerization. In addition, polymers with various topologies (e.g., block, random, star, end-functional and in-chain functional copolymers [for example, of styrene and methyl (meth)acrylate]) have been synthesized using the present process. The polymeric products encompassed by the present invention can be widely used as plastics, elastomers, adhesives, emulsifiers, thermoplastic elastomers, etc.

A thermosetting powder coating composition extruder system including an extruder body and an injection system is disclosed. The extruder body includes segments surrounding one or more rotating screws. A first segment's main inlet receives material, such as from a pre-mix hopper, and a final segment's outlet discharges extrudate. A low pressure injector injects additives, particularly those that are hard to incorporate, into one or more segments at one or more injection positions at the main inlet or between the main inlet and the outlet. The injector includes a source of pressurization coupled to a pressure vessel, a pressure regulator maintaining the pressure at or below a given level, a flow regulator, and an injection port. A sensor adjacent the outlet monitors the physical characteristics of the extrudate and is coupled to a controller of the low pressure injector for dynamic control thereof.

Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

The invention relates to a suspension hydraulic damper (1) comprising a tube (2) filled with working liquid, inside of which a slidable piston assembly (3), provided with compression (12) and rebound (11) valve assemblies and attached to a piston rod led outside the damper, is placed, and at least one additional compression valve system (18, 19). To increase an amount of dissipated energy during extremely fast compression strokes the compression valve system (18, 19) comprises at least one substantially thin closing element, preferably in a form of a flat floating disc (24, 34), having an outside diameter less than the inner diameter of the tube (2) and being axially slidable with respect to the piston rod (4) axis, a spring (23, 33) surrounding the piston rod (4) axis and pressing the closing element against a retainer (26, 35) into open position, an abutting surface (28, 38) for the closing element (24, 34) in closed position, and at least one passage (25, 31) for the flow of damping medium in closed position.

A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical / non-medical objects. It can be used to prepare single or multiple articles.

The invention relates to a hydraulic damper, in particular for the suspension system of a motor vehicle, comprising a tube filled with working fluid; a piston assembly slidably positioned inside the tube; a fluid compensation chamber located outside of the tube, and a base valve assembly at the end of the tube for controlling the flow of working fluid between the tube and the compensation chamber. A compression valve module added between the piston assembly and the base valve assembly allows the damping to increase during extremely fast compression strokes without modification of the other damper components, affecting neither tuning options nor performance in a normal operating range of piston velocities.

The invention relates to a blender device comprising: a rotor (2) designed to engage with motor means (4) in order to be rotated; and an annular ring (5) enclosing the rotor (2) and having at least one axial orifice and a plurality of radial orifices (6) for the passage of the blend; and an admission duct (7) for admitting particles intended to be incorporated into the blend, leading into the interior of said annular ring (5). The invention also relates to a blender assembly equipped with such a device and a process for producing an emulsion.

This disclosure pertains to a method and apparatus to permit changing a filter on the input line to a vacuum deposition chamber without breaking or reducing the vacuum for the deposition chamber and other components in the deposition system. Isolation valves are provided at the inlet and outlet of the filter so the filter can be isolated from the source of vacuum and the deposition chamber for removal and replacement of the filter.

The invention concerns a pourer (3) associated with a closure cap (1) and designed to be fixed inside a container neck (9), comprising a peripheral skirt (4), a pouring element (8), and means for temporarily assembling said pourer and said closure cap. The invention is characterised in that: a) said peripheral skirt (4) comprises a lower part (5) capable of being radially spaced apart for the pourer to be fixed to the neck; b) the pourer (3) comprises a rigid component (6) axially mobile downwards, inside the peripheral skirt (4); c) the pourer (3) comprises means for causing the lower part (5) and the rigid component (6) to co-operate so as to transform the axial movement of the rigid component (6) into a radial movement of the lower part (1).

A method for recovering liquefied natural gas from a gas mixture containing natural gas and impurities by subjecting the natural gas to a series of steps beginning with feeding a natural gas stream containing impurities to a nitrogen rejection unit; feeding the purified natural gas stream to a liquefier heat exchanger; expanding the liquefied natural gas and feeding the expanded liquefied natural gas to a flash vessel; flashing the liquid natural gas and separating the liquefied natural gas from the flash gas; and feeding the liquefied natural gas to storage and the flash gas to the nitrogen rejection unit.

Recovering high purity benzene from hydrocarbon feedstock containing aromatics and non-aromatics is implemented by simple and low-cost modifications to conventional extractive distillation columns (EDCs). Methyl cyclohexane (MCH) that is generated through non-selective hydrogenation of toluene in hydrodesulfurization (HDS) units is a major contaminant in benzene production. To meet MCH specifications, often times the extractive distillation (ED) process for recovering purified benzene is operated with excessive benzene loss to the overhead raffinate stream, producing a lower quality non-aromatic product. Novel techniques (1) remove operational constrictions of the HDS unit on MCH production, thus lengthening the catalyst life and (2) allow the EDC to drive essentially any amount of MCH away from the bottom benzene product without concerns with benzene loss to the overhead raffinate stream and (3) recover benzene from the overhead raffinate stream to upgrade the quality of non-aromatic product and increase the benzene product recovery.

A lubrication system comprising a motor, a positive displacement pump driven by the motor, a lubricant container in fluid communication with the positive displacement pump and at least one lubricant outlet in fluid communication with the lubricant container. The positive displacement pump is arranged to carry out at least one discharge stroke to dispense lubricant from the at least one lubricant outlet when the lubrication system is in use. The lubrication system also comprises a control unit that is arranged to determine an amount of lubricant that is dispensed from the lubricant container via the at least one lubricant outlet when the lubrication system is in use. The control unit is arranged to monitor current supplied to the motor to obtain a motor current signal, and to determine a number of the discharge strokes from the motor current signal.

Methods and apparatus for improving the efficiency and effectiveness of in situ reduction of a Fischer-Tropsch catalyst slurry. The preferred embodiments of the present invention are characterized by a system that utilizes a co-feed of carbon monoxide along with the reducing gas into a reduction vessel maintained at an elevated temperature. As the metal oxide reduces to the active Fischer-Tropsch metal, the carbon monoxide acts as a poison to hydrogenolysis and reduces the loss of liquid from the slurry and the production of methane. The carbon monoxide is generally in parts-per-million quantities and will achieve the desired results in quantities less than 5,000 ppm, preferably less than 2,000 ppm.

A cleaning station for a capsule filling and closing machine has a number of segment blocks each having receptacles which carry some product residue that needs to be removed for the machine to operate efficiently and productively. A brush is placed in each receptacle to engage its interior wall, and compressed air is directed toward the interior wall just behind the brush. The moving brush and compressed air blast remove the product residue on the interior wall, and the dislodged residue, with assistance from a vacuum source, is moved out of the receptacle.

The invention relates to a hydraulic damper, in particular for the suspension system of a motor vehicle, comprising a tube filled with working fluid; a piston assembly slidably positioned inside the tube; a fluid compensation chamber located outside of the tube, and a base valve assembly at the end of the tube for controlling the flow of working fluid between the tube and the compensation chamber. A compression valve module added between the piston assembly and the base valve assembly allows the damping to increase during extremely fast compression strokes without modification of the other damper components, affecting neither tuning options nor performance in a normal operating range of piston velocities.

The present invention provides a golf ball material made of an ionomer blend composition of (a) at least one E / X copolymer and / or E / X / Y terpolymer and (b) at least one polyfunctional higher aliphatic acid with two or more functionalities that has a molecular weight of at least about 200 but less than about 1,500, in which components (a) and (b) are neutralized with (c) an oxygen-containing inorganic metal compound. The copolymer and terpolymer of component (a) is one or a mixture of two or more selected from the group consisting of copolymers and terpolymers which is partially neutralized with metal ions, copolymers and terpolymers which are completely neutralized with metal ions, and unneutralized copolymers and terpolymers. The golf ball material has a good thermal stability, flow properties and moldability, making it suitable for injection molding. The material is ideal for forming high-performance golf balls of excellent durability, scuff resistance and optimal hardness, without any loss in the rebound resilience of moldings obtained therefrom.

The present invention relates generally to the fields of chemistry and radionuclide imaging. More particularly, it concerns compositions, kits and methods for imaging and therapy involving N4 compounds and derivatives.

The invention relates to a system for evaluating the efficiency of a wind turbine (3), with a control system comprising means (11, 15) which are used to measure meteorological parameters M1, M2 and are respectively arranged in the wind turbine (3) and in a meteorological tower (5), and means (13) for measuring the orientation β of the wind turbine and the power Pr generated by same. The system according to the invention comprises a computerised unit (21) which is connected to said measuring means (11, 13, 15) and provided with a first calculating module (23) designed to obtain a characteristic power Pc as a function of said parameters from the data obtained during a first operating step, and a second calculating module (25) designed to obtain the mean deviation Dm between the power Pr actually generated and the characteristic power Pc according to the function obtained by the first calculating means (23) in the set of at least one series of data.

A delivery pump for conveying a liquid between a pump inlet and a pump outlet, the pump being constructed as a single-stage centrifugal pump with a radial impeller (2) having a centrifugal construction arranged rotatably in an impeller chamber (6) of a pump casing (1); the impeller being connected to a variable-speed drive motor (5) variable in speed into the five-digit range of revolutions per minute, and the impeller receiving liquid flow centrally, and being provided with radially-extending delivery ducts (3), and at outside impeller diameters of up to 55 mm developing rotational speed-dependent delivery heads of up to 300 m. For use in a process engineering system, the delivery pump is designed for nominal operation in the form of continuous centrifugal pump part-load operation with delivery rates in the range of 0 ml / min to 7000 ml / min; the nominal operation is characterized by a centrifugal pump part-load-specific rotational speed nqTL≧0.05≦10 (l / min), and the impeller chamber (6) comprises one or more pump outlet ducts (13) located on the circumference at acute angles to or tangentially to the outside diameter of the radial impeller.

A treatment plant in particular for a liquid medium of average to high viscosity, for example for production of pharmaceutical and cosmetic products includes a container in which an agitator, built-in structures, heat exchange elements, baffles or the like may be arranged. To reduce medium loss and to effectively clean such a treatment plant, any region or component of the treatment plant that comes into contact with the fluid medium is provided with a medium-repellent coating.