The invention discloses a miniaturization and high-stability radio-frequency signal output module which comprises a medium-power amplifying module, a single-pole single-throw switch, a coupler, a low-pass filter and an isolator. Input of the medium-power amplifying module is connected with a signal input end. Output of the medium-power amplifying module is connected with input of the coupler through the single-pole single-throw switch. One path of output of the coupler is connected with input of the isolator through the low-pass filter. Output of the isolator is connected with a signal output end. Other two paths of output of the coupler are coupling output and detection output respectively. The miniaturization and high-stability radio-frequency signal output module has ideal impedance matching, system stability is enhanced, meanwhile, non-linear distortion is weakened, an amplifier port is good in standing wave performance, the using stability of an amplifier is improved, the single-pole single-throw switch is used, so that output module loss is lowered, the isolation degree is improved, switch response time is shortened, and meanwhile the output module has the advantages of being simple in circuit structure, low in cost, good in signal output effect and the like.