35results about How to "Effective product quality" patented technology

The invention discloses a preparation containing herba violae, rhizoma cyperi and herba leonuri and a preparation method and a detection method of the preparation. The preparation is prepared by the following raw materials in parts by weight: 500-700 parts of perfoliote knotweed herb, 500-700 parts of herba violae, 500-700 parts of red rhizoma smilacis glabrae, 400-600 parts of cortex phellodendri, 300-500 parts of herba leonuri, 300-500 parts of caulis sargentodoxae, 300-500 parts of radix sophorae flavescentis and 200-400 parts of rhizoma cyperi. Compared with the prior art, the medicine provided by the invention is few in components, rigorous in structure and exact in efficacy, and corresponds to a method of diagnosis and treatment based on syndrome differentiation treatment of traditional Chinese medicines. The provided preparation method not only reduces paste extraction rate of the traditional Chinese medicine extraction, improves contents of effective ingredients, guarantees stability of efficacy, solves the problem of poor stability and strong hygroscopicity in a preparation process, and also greatly reduces the production cost. The provided detection method is strong in specificity and accurate in detection result, and can effectively control quality of the medicine; and therefore, the clinical efficacy of the medicine is ensured.

A cable management apparatus includes a half housing and a plurality of partitions. The half housing has a first side surface and a second side surface opposite to each other. The partitions are disposed in the half housing to divide the interior of the half housing into a plurality of compartments, and each compartment extends to the two faces of the half housing. A plurality of signal cables are respectively disposed into the compartments, so that the signal cables are able to be disposed in the electronic slots through the half housing and that the signal cables are electronically connected to the corresponding pins respectively.

The invention provides Chinese medicine preparation for external use for treating rheumatism and rheumatoid disease and the preparation method thereof. The preparation is prepared by using large leaf gentian roots, Chinese clematis, gum mastic, myrrh, momordica cochinchinensis(Lour.) spreng, castor seeds, and sesame oil. The gum mastic and the myrrh are pulverized into fine powder, the large leaf gentian roots are boiled by adding water, and plaster is obtained after filter liquor is decompressed and concentrated. The Chinese clematis is soaked in the sesame oil, the momordica cochinchinensis(Lour.) spreng and the castor seeds are soaked in the obtained medical oil, and then beaten to be slurry, beeswax is added into the obtained medical oil for melting, then the fine powder, the plaster, the slurry and the medical oil are mixed evenly, and various preparation formulations are produced according to conventional preparation craft. Compared with the prior art, the invention uses the common Chinese medicines as the raw materials, the used raw materials are in a small variety, the product quality is easy to be controlled, the effective components of the raw material medicines are obtained after extraction, to be more easily absorbed and to exert the drug efficacy, thereby providing a medicine for external use for treating rheumatism and rheumatoid disease with low administration cost and good curative effect.

The invention discloses a soft blank cutting method and a soft blank cutting device. The method comprises the following steps: a linear steel wire cutter moves to realize soft blank cutting; in a movable cutting process of the steel wire cutter, an inclined angle being more than zero is formed between the steel wire cutter and the horizontal plane; the steel wire cutter moves along the tension direction of the steel wire cutter when doing vertical undercutting movement; after the steel wire cutter finishes cutting, the steel wire cutter does resetting movement on a vertical undercutting face by bypassing a soft blank; the cutting device comprises a steel wire cutter driving device and a steel wire constant tension device, wherein the steel wire cutter driving device is composed of a chain wheel ring and a dynamic tracking and guiding device. According to the soft blank cutting method and the soft blank cutting device, the cutting process of the deformable linear steel wire cutter can be controlled by coordinating cutting movement and matching equipment, so that the one-way effective cutting of reciprocated cutting movement in a continuous conveying process of a strip-shaped blank is realized and the cutting requirements that the deformation of a cut section of an extruded and molded soft mud blank is small are met; the effective service life of a steel wire type cutter without blades is prolonged.

The invention discloses a process for preparing a water-soluble ginkgo biloba extract used for injection, which comprises the following steps: preparing a medicinal gelatin aqueous solution of 0.1-0.3 percent; dissolving the water-soluble ginkgo biloba extract by the gelatin aqueous solution; ultrafiltering and drying the dissolved ginkgo biloba extract in vacuum to prepare total ginkgo terpene lactones and a total ginkgo flavone-glycoides extract; and generally mixing the components according to respective contents so as to prepare a finished product. In the water-soluble ginkgo biloba extract, the content ratio of total flavonol glycosides to the total ginkgo terpene lactones is 4:1, thus the water-soluble ginkgo biloba extract can be used as a water-soluble ginkgo injection raw material, thereby enlarging the range of application and ensuring the safety, the effectiveness, the stability and the controllability of product quality.

The invention discloses a method for measuring the content of ginsenoside in a heart-benefiting preparation. The method is a high performance liquid chromatography method for gradient elution by taking ginsenoside Rg1, Re, Rb1 and Rc contrasts as contrasts, methyl alcohol as a flowing phase and a 0.02-2% phosphoric acid aqueous solution as a flowing phase B. The method can be used for quickly and accurately measuring the contents of ginsenoside Rg1, Re, Rb1 and Rc components in the heart benefiting preparation in a high-repetitiveness and high-recycling-rate manner.

The invention discloses a quality detection method of a five-flavor manna medicine bath preparation. The five-flavor manna medicine bath preparation is made from raw materials of Juniperus formosana, ephedra, rhododendron anthopogonoide, myricaria and artemisia sieversiana according to a conventional method of pharmaceutics. On the basis of the primary standard, the thin layer chromatography of ephedra and rhododendron anthopogonoide is revised, the thin layer chromatography of Juniperus formosana and artemisia sieversiana is added. Under the simple and convenient condition of mobile phase, octyl silane bonding silica gel or phenyl bonding silica gel is used as filler, and simultaneously, the contents of ephedrine hydrochloride and pseudoephedrine hydrochloride in the ephedra are detected. The invention also provides a method for measuring the content of hyperoside in five-flavor manna preparation rhododendron anthopogonoide, thus ensuring the safety, effectiveness and controllability of product quality. By the quality detection method, the quality standard of the existing five-flavor manna medicine bath preparation is improved correspondingly.

The invention discloses a method for measuring content of atractylis in a joint arthralgia-relieving pill. The method is a high performance liquid chromatography method which takes an atractylis reference substance as a reference and takes methanol, water, 0.01-5% phosphoric acid aqueous solution, 0.01-5% glacial acetic acid and 0.01-0.5% formic acid aqueous solution in a ratio of (50-70): (50-30)or acetonitrile, water, 0.01-5% phosphoric acid aqueous solution, 0.01-5% glacial acetic acid and 0.01-0.5% formic acid aqueous solution in a ratio of (20-50): (80-50) as a mobile phase. The method disclosed by the invention is high in specificity, high in precision, high in repeatability, high in recovery rate, high in stability and accurate in measurement result, the aim of effectively controlling the quality of medicines is achieved, and the stability of the product quality and the safety and effectiveness of clinical medication are ensured.

The invention relates to a detection method of compound danshen dripping pills, comprising the following contents of: observation of characters, discrimination of contents, inspection of contents, comparison of finger prints and assaying of contained components. The detection method provided by the invention comprises a discriminating method of the medicinal component panax notoginseng, the discriminating method adopts thin-layer chromatography, the reference materials adopt a panax notoginseng reference medicinal material, a ginsenoside Rg1 reference substance, a ginsenoside Re reference substance, a ginsenoside Rb1 reference substance and a panax notoginseng saponin R1 reference substance. The detection method provided by the invention also comprises a discriminating method and an assaying method of the medicinal component danshen, wherein the discriminating method adopts a sub-2 mu m liquid chromatography technology to perform chromatographic fingerprint discrimination, and adopts sodium danshensu as a reference material; and the assaying method adopts a sub-2 mu m liquid chromatography technology to perform assaying on the components such as danshensu, panax notoginseng saponin R1, ginsenoside Rg1 and ginsenoside Rb1 in the danshen.

The invention discloses a method for determining specnuezhenide content in a Zhenqifuzheng preparation. Taking specnuezhenide standard as contrast, the method can determine the specnuezhenide content in the Zhenqifuzheng preparation by high-performance liquid chromatography by selecting a solution containing methanol and a mixed solution with a ratio of (20-50):(80-50) or a mixed solution containing acetonitrile and the mixed solution with a ratio of (5 to 35):(95-65), wherein the mixed solution consists of water, 0.01% to 5% of phosphoric acid water solution, 0.01% to 5% of glacial acetic acid, 0.01% to 0.5% of methanoic acid water solution. Compared with the prior art, the method provided by the invention has the advantages of high specificity, high precision, high repeatability, high yield, high stability, and accurate result by adopting high-performance liquid chromatography, and can effectively control the preparation quality, thereby ensuring the stability of product quality as well as clinical safety and effectiveness.

The invention discloses a method for measuring content of formononetin in a Zhenqifuzheng preparation. The method is a high-performance liquid chromatography with a formononetin reference substance used as a contrast and the ratio of methyl alcohol to water / a 0.01%-5% phosphoric acid aqueous solution / a 0.01%-5% glacial acetic acid / a 0.01%-0.5% formic acid aqueous solution of (50-70):(50-30) or the ratio of acetonitrile to the water / the 0.01%-5% phosphoric acid aqueous solution / the 0.01%-5% glacial acetic acid / the 0.01%-0.5% formic acid aqueous solution of (20-50):(80-50) used as a mobile phase. The method is high in specificity, high in accuracy, good in repeatability, high in recovery rate, high in stability, accurate in measurement result and capable of achieving the purpose of effective control of the drug quality and ensuring the stability of the product quality and the safety and the effectiveness of clinical medication.

The invention discloses a method for measuring the content of ursolic acid in a glossy privet fruit and astragalus membranaceus healthy energy-strengthening preparation. The method takes an ursolic acid reference substance as a reference and can be used for measuring the content of the ursolic acid in the glossy privet fruit and astragalus membranaceus healthy energy-strengthening preparation at the wavelength being 200-220nm by using a high-performance liquid chromatography. The method is high in specificity and precision, good in repeatability, high in recovery rate and stability and accurate in measurement result, achieves the purpose of effectively controlling the quality of drugs so as to ensure the stable product quality and the safe and effective clinical treatment.