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65results about How to "Decrease the declination" patented technology

Pharmaceutical methods, dosing regimes and dosage forms for the treatment of Alzheimer's disease

InactiveUS20050042284A1Improving and lessening rate of declineReduction of the decline in saidBiocideNervous disorderDosing regimenGuideline
In general, the invention relates to a pharmaceutical dose having R-flurbiprofen as the active ingredient that upon oral administration of a single dose to a fasting subject provides a Cmax of about 30-95 μg per mL. When the dose is administered to an individual having mild-to-moderate Alzheimer's disease (or desiring protection against Alzheimer's disease) twice daily for at least 4 months according to the described guidelines, an improvement or lessening in decline of cognitive function as characterized by cognition tests is observed in the patient. The composition of the invention is formulated with one or more pharmaceutically acceptable excipients, salts or carriers.
Owner:MYRIAD GENETICS

Electrophotographic photoconductor, electrophotographic apparatus and process cartridge

The present invention aims to provide a photoconductor having improved wear resistance, and which has reduced foreign matter attached on the photoconductor surface.The electrophotographic photoconductor of the present invention is formed by sequentially disposing a photoconductive layer comprising at least one layer and a protective layer on an electroconductive support, and the protective layer comprises an acrylic resin and / or a methacrylic resin and a resin composition comprising an acryl-modified polyorganosiloxane compound which is dispersed in or compatible with the acrylic resin and / or the methacrylic resin.
Owner:RICOH KK

Isolated Renal Cells and Uses Thereof

ActiveUS20110117162A1Reduce declineImprove renal functionBiocidePharmaceutical delivery mechanismUrologyKidney cell
The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
Owner:PROKIDNEY

Methods for tracking the progression of Alzheimer's disease identifying treatment using transgenic mice

A method of screening pharmaceutical drugs, gene therapies, vaccines, dietary supplements, behavioral and environmental therapies and other clinical treatments for potential efficacy in the treatment of Alzheimer's disease in humans. The method includes selecting transgenic mice that are genetically altered for Alzheimer's disease and using measurement and / or imaging techniques to determine the activity level of the posterior cingulate region of the brains of the mice after treatment. Based on these measurements and comparisons to a control group, the effectiveness of the treatment in arresting or reversing Alzheimer's disease in mice can be determined, and the treatment can be identified as a promising candidate for human trials.
Owner:REIMAN ERIC M

Voice code conversion method and apparatus

It is so arranged that a voice code can be converted even between voice encoding schemes having different subframe lengths. A voice code conversion apparatus demultiplexes a plurality of code components (Lsp1, Lag1, Gain1, Cb1), which are necessary to reconstruct a voice signal, from voice code in a first voice encoding scheme, dequantizes the codes of each of the components and converts the dequantized values of code components other than an algebraic code component to code components (Lsp2, Lag2, Gp2) of a voice code in a second voice encoding scheme. Further, the voice code conversion apparatus reproduces voice from the dequantized values, dequantizes codes that have been converted to codes in the second voice encoding scheme, generates a target signal using the dequantized values and reproduced voice, inputs the target signal to an algebraic code converter and obtains an algebraic code (Cb2) in the second voice encoding scheme.
Owner:FUJITSU LTD

Isolated renal cells and uses thereof

The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
Owner:PROKIDNEY

Audio encoding apparatus and audio encoding method

An audio encoding apparatus comprising: a power calculation unit that calculates a power fluctuation ratio based on the input signal; a calculation unit that calculates a prediction gain fluctuation ratio based on the input signal; and a block length judging unit that selects one of encoding using a long block mode segmenting an input signal into frames each consisting of a predetermined number of samples and encoding each of the frames, and encoding using a short block mode segmenting each of the frames into short blocks and encoding each of the short blocks, based on the power fluctuation ratio and the prediction gain fluctuation ratio.
Owner:FUJITSU LTD

Compounds for alzheimer's disease

The invention provides novel compounds useful for the treatment of neurodegenerative disorders including Alzheimer's disease and dementia. The compounds have a substituents chosen from -L-C(═O)OH, -L-CH═CHC(═O)OH, -L-C(═O)NH2, -L-C(═O)NH(C1-3 alkyl), -L-C(═O)N(C1-3 alkyl)2, -L-S(═O)2(C1-3alkyl), -L-S(═O)2NH2, -L-S(═O)2N(C1-3 alkyl)2, -L-S(═O)2NH(C1-3 alkyl), -L-C(═O)NHOH, -L-C(═O)CH2NH2, -L-C(═O)CH2OH, -L-C(═O)CH2SH, -L-C(═O)NHCN, -L-NHC(═O)ORo, -L-C(═O)NHRo, -L-NH(C═O)NHRo, -L-C(═O)N(Ro)2, -L-NH(C═O)N(Ro)2, -L-sulfo, -L-(2,6 difluorophenol), -L-phosphono, and -L-tetrazolyl, where L is a linker.
Owner:MANFREDI JOHN

Speech synthesizing method and apparatus

An amplitude altering magnification (r) applied to sub-phoneme units of a voiced portion and an amplitude altering magnification s to be applied to sub-phoneme units of an unvoiced portion are determined based upon a target phoneme average power (p0) of synthesized speech and power (p) of a selected phoneme unit. Sub-phoneme units are extracted from a phoneme to be synthesized. From among the extracted sub-phoneme units, a sub-phoneme unit of the voiced portion is multiplied by the amplitude altering magnification (r), and a sub-phoneme unit of the unvoiced portion is multiplied by the amplitude altering magnification (s). Synthesized speech is obtained using the sub-phoneme units thus obtained. This makes it possible to realize power control in which any decline in the quality of synthesized speech is reduced.
Owner:CANON KK

Method of manufacturing dielectric film

The present invention provides a method of manufacturing a dielectric film having a high permittivity. An embodiment of the present invention is a method of manufacturing, on a substrate, a dielectric film including a metallic oxynitride containing an element A made of Hf or a mixture of Hf and Zr, an element B made of Al, and N and O. The manufacturing method includes: a step of forming a metallic oxynitride whose mole fractions of the element A, the element B, and N expressed as B / (A+B+N) has a range of 0.015≦(B / A+B+N))≦0.095 and N / (A+B+N) has a range of 0.045≦(N / (A+B+N)) and a mole fraction O / A of the element A and O has a range expressed as 1.0<(O / A)<2.0, and having a noncrystalline structure; and a step of performing an annealing treatment at 700° C. or higher on the metallic oxynitride having a noncrystalline structure to form a metallic oxynitride including a crystalline phase with a cubical crystal incorporation percentage of 80% or higher.
Owner:CANON ANELVA CORP

Deep hole and ultra-deep hole static cone penetration test method and apparatus

The invention relates to a deep hole and ultra-deep hole static cone penetration test method and apparatus. The apparatus is provided with two to five sleeves with diameters from large to small, and each of all the sleeves is provided with a sleeve connector matched with the corresponding sleeve except the sleeve with the largest diameter. Each sleeve connector is provided with an annular tray, and threads are formed in the upper opening and the lower opening of each sleeve connector. When testing is carried out, a static cone penetration test is carried out by adopting a conventional static cone penetration method, the frictional resistance of the side wall of a feeler lever is too large, transmission cannot be effectively carried out to a cone penetration probe, and the depth of cone penetration is affected, overlaying soil is drilled in advance in a preboring manner, the apparatus is protected additionally, and the diameter ratios, the number of layers of the sleeves and the buried depth are selected according to the depth of cone penetration and the requirements for sleeve reducing. The sleeve with the largest diameter is buried in soil and serves as a fixing sleeve with soil friction, and the other sleeves are lowered one after another and are hung on the sleeve on the outermost layer through the annular trays. Hole cleaning is carried out to the preset depth, the static cone penetration probe and the feeler lever are used for testing through the sleeve with the smallest diameter and an alloy bit. With the deep hole and ultra-deep hole static cone penetration test method and apparatus, the deflection angle of the probe can be decreased, and the test depth can be increased.
Owner:CHINA MAJOR BRIDGE ENERGINEERING

Floating crane, multifunctional suspension hook thereof and multifunctional suspension hook group

The invention discloses a floating crane, a multifunctional suspension hook thereof and a multifunctional suspension hook group, wherein, the multifunctional suspension hook comprises a fixed pulley block, a movable pulley block, a guiding pulley block, a suspension hook and a wire rope, and the fixed pulley block is vertically swung using a first shaft pin as a shaft; a guiding pulley block is horizontally swung using a second shaft pin as a shaft; the movable pulley block is arranged below the fixed pulley block, and the suspension hook is installed at the lower end of the movable pulley block; the wire rope winds the guiding pulley block, the movable pulley block, the fixed pulley block, the movable pulley block and the guiding pulley block in sequence. The multifunctional suspension hook provided by the invention can realize horizontal swing and vertical swing in the hoisting plane, and two multifunctional suspension hooks are combined to form a floating crane with the multifunctional suspension hook group, thereby realizing turning over of the large structural piece, simple assembly and few hook changes without auxiliary hanging beams, and facilitating the hoisting work with high efficiency.
Owner:CHINA MERCHANTS HEAVY IND JIANGSU +1

Four-winding-drum hoisting mechanism and container crane

The invention discloses a four-winding-drum hoisting mechanism and a container crane. A first winding drum, a second winding drum, a third winding drum and a fourth winding drum are arranged on a trolley. A first fixed pulley, a second fixed pulley, a third fixed pulley and a fourth fixed pulley are arranged on the trolley. A first movable pulley block, a second movable pulley block, a third movable pulley block and a fourth movable pulley block are arranged on a hoisting appliance. A first steel wire rope is drawn out from the first winding drum and wound on the first movable pulley block and the first fixed pulley. A second steel wire rope is drawn out from the second winding drum and wound on the second movable pulley block and the second fixed pulley. A third steel wire rope is drawn out from the third winding drum and wound on the third movable pulley block and the third fixed pulley. A fourth steel wire rope is drawn out from the fourth winding drum and wound on the fourth movable pulley block and the fourth fixed pulley. According to the four-winding-drum hoisting mechanism and the container crane, the hoisting appliance can incline forwards, backwards, leftwards and rightwards, rotate and stably hoist by means of the differential control over the four winding drums, and driving anti-swing and driven swing reduction can be achieved. In addition, the stress of the hoisting mechanism is optimized, the total weight of the trolley is decreased, and the manufacturing cost is low.
Owner:SANY MARINE HEAVY IND

Plasma processing apparatus and method of producing amorphous silicon thin film using same

Disclosed is a plasma processing apparatus, wherein a plasma-generating electrode has a plurality of gas exhaust holes which run through the plasma-generating electrode from the surface facing a substrate held by a substrate-holding mechanism, and reach a gas exhaust chamber; gas-feeding pipes, provided connected to a gas-introducing pipe, have gas-feeding ports for discharging source gas toward the inside of the plurality of gas exhaust holes; and the gas-feeding pipes and the gas-feeding ports are arranged in a manner such that extended lines, representing the direction of the flow of the source gas discharged from the gas-feeding ports, intersect the end surface open regions at the interface of the gas exhaust chamber to the gas exhaust holes. Also disclosed is a method of producing the amorphous silicon thin film using the plasma processing apparatus.
Owner:TORAY IND INC

Side-driving-type all-position automatic welding trolley traveling mechanism for pipeline

InactiveCN109702400AReduce processing and assembly difficultyImprove stabilityWelding/cutting auxillary devicesAuxillary welding devicesCamEngineering
The invention relates to a side-driving-type all-position automatic welding trolley traveling mechanism for a pipeline. The side-driving-type all-position automatic welding trolley traveling mechanismis constituted by four sets of following assemblies which are the same in structure, and double floating locking structures; the double floating locking structures enable the following assemblies tobe attached to and press a rail tightly, and a welding trolley is driven through friction force to travel along the rail; the double floating locking structures are constituted by driving devices, sliding locking devices and cam devices; the sliding locking devices are matched with U-shaped grooves in a box body, and thus the sliding locking devices make horizontal linear sliding on the box body;the driving devices are arranged in the sliding blocking devices, and thus the driving devices and the sliding locking devices make relative linear movement; the lower sides of the cam devices and thebox body are connected; the four sets of following assemblies can be mutually exchanged, and the machining and assembling difficulty is lowered; the declination angle of a following wheel is reduced,and as for small-pipe-diameter welding, the stability can be effectively improved; and the following wheel and a driving wheel are arranged in a floating mode, pressing force of the driving wheel forthe rail is directly adjusted by adjusting compression force of a rubber spring, normal operation of the welding trolley is ensured, and abrasion of the driving wheel to the rail is reduced.
Owner:LUOYANG DEPING TECH

Pharmaceutical composition and method

InactiveUS20090155903A1Improvement and lessening in declineDecline of cognitive functionOrganic chemistryTissue cultureMedicineTherapeutic treatment
The invention provides compounds, pharmaceutical compositions and methods for the therapeutic treatment and prevention of neurodegenerative disorder and other Aβ42-related diseases and disorders.
Owner:MYRIAD GENETICS

Power-taking device for automatic wiring device of ground wire deicing

Disclosed is a power-taking device for an automatic wiring device of ground wire deicing. Currents of transmission leads of iron towers are guided to combination, are guided to an opening-closing conducting device, and then are led to carry out deicing on a ground wire of the iron tower. The power-taking device comprises a power-taking device wire clamp and contact finger structures; an external expansion side is arranged at the side of the power-taking device wire clamp; and the contact finger structures are arranged at the external expansion side of the power-taking wire clamp. A plurality of groups of contact finger structure with springs are designed on the power-taking device; and the currents of the power-taking device are guided to the opening-closing conducting device.
Owner:NANJING POWER FITTINGS DESIGN & RES INST CO LTD

Wind turbine generator and method of controling the same

The present invention provides a wind turbine generator and a method of controlling the same which can prevent the decline in power generation efficiency even when the generator is located where the wind is not always strong. The wind turbine generator mainly includes an anemometer, an anemoscope, a nacelle swiveling mechanism which turns a nacelle, and a control unit which controls the nacelle swiveling mechanism. The control unit controls the nacelle swiveling mechanism so as to swivel the nacelle based on the wind direction obtained from the measurement result of the anemoscope when the wind speed obtained from the measurement result of the anemometer is greater than a first threshold Vth1 which is smaller than a cut-in wind speed Vcut<sub2>—< / sub2>in, and controls the nacelle swiveling mechanism so as to stop the swiveling of the nacelle when the wind speed obtained from the measurement result of the anemometer is not greater than a first threshold Vth1.
Owner:MITSUBISHI HEAVY IND LTD

Multi-rope lifting system for ultra-deep vertical shaft and guiding method of multi-rope lifting system

The invention discloses a multi-rope lifting system for an ultra-deep vertical shaft and a guiding method of the multi-rope lifting system, and belongs to the technical field of mine lifting. The multi-rope lifting system comprises an upper guiding wheel system, a lower guiding wheel system, a front lifting container, a rear lifting container, a driving unit, a front lifting rope, a rear lifting rope, a tail rope and a plurality of balance head ropes, wherein the front lifting rope is lapped on the upper guiding wheel system, one end of the front lifting rope is connected with the top of the front lifting container, and the other end of the front lifting rope is connected with the driving unit; the rear lifting rope is lapped on the lower guiding wheel system, one end of the rear lifting rope is connected with the top of the rear lifting container, and the other end of the rear lifting rope is connected with the driving unit; one end of the tail rope is connected with the bottom of thefront lifting container, and the other end of the tail rope is connected with the bottom of the rear lifting container; and the balance head ropes are lapped on the upper guiding wheel system, one end of each balance head rope is connected with the top of the front lifting container, and the other end of each balance head rope is connected with the top of the rear lifting container. According tothe multi-rope lifting system, the balance head ropes are arranged, so that the traction load borne by the driving unit is greatly reduced, the effective service life of the driving unit is greatly prolonged, and the multi-rope lifting system for the ultra-deep vertical shaft can carry out lifting operation with larger load.
Owner:CHINA UNIV OF MINING & TECH

Wireless communication device, method, and recording medium

In order to enable reducing a possibility of being unable to connect to an AP in which a failure of a network connection occurs and also lessening a decline in a communication rate, a wireless communication method includes: detecting occurrence of a failure of a network connection in a first wireless communication device, when detecting the occurrence of the failure, determining whether or not to make a first wireless connection to the first wireless communication device, when making the determination to make the first wireless connection, making the first wireless connection to the first wireless communication device, and relaying a first communication between the first wireless communication device and a network.
Owner:NEC PLATFORMS LTD

Ultra-low distortion large viewing field telecentric optical system

InactiveCN102023369AEvenly dispersedReduce off-axis aberrationsOptical elementsCamera lensLow distortion
The invention relates to an ultra-low distortion large viewing field telecentric optical system. The ultra-low distortion large viewing field telecentric optical system comprises a first negative lens, a first positive lens, a second negative lens, a diaphragm, a third negative lens, a second positive lens and a third positive lens which are sequentially arranged on the same optical path. The ultra-low distortion large viewing field telecentric optical system can meet the requirements of a positioning system on high precision and illumination uniformity in different viewing fields, has uniform dispersion in various viewing fields and can ensure that the lenses do not have vignetting.
Owner:XI'AN INST OF OPTICS & FINE MECHANICS - CHINESE ACAD OF SCI

Lifting device

The invention relates to a lifting device which is suitable for being used for lifting of a traveling crane, a gantry crane, a hoist and the like. The lifting device comprises a winding drum which is driven by a motor, a fixed pulley assembly close to the winding drum on the upper portion of the lifting device and a movable pulley assembly on the lower portion of the lifting device. The fixed pulley assembly is composed of two fixed pulley groups, and the axial directions of the fixed pulley groups are perpendicular to the axial direction of the winding drum. The movable pulley assembly is composed of two movable pulley groups, and the axial directions of the two movable pulley groups are in a V shape. The lifting device is further provided with a lifting rope. After the lifting rope crosses the two fixed pulleys on the two fixed pulley groups, two ends of the lifting rope are respectively downward wound sequentially between the movable pulley groups and the fixed pulley groups, and then, the lifting rope is wound evenly on the winding drum upward on the movable pulley groups and eventually fixedly arranged at the left end and the right end of the winding drum. The lifting device is small in appearance and size, simple in structure and light in weight.
Owner:江苏武东机械有限公司

Digital low-light sighting telescope optical system

ActiveCN102495464BMeet the needs of visual observation and aimingDecrease the declinationTelescopesMagnifying glassesFiberEyepiece
The invention discloses a digital low-light sighting telescope optical system which comprises a main optical path which is formed by an object lens system, an image intensifier and an ocular lens system, wherein a light composition prism, an image rotation system, a light splitting prism and a CCD relay system are arranged between the image intensifier and the ocular lens system, the light composition prism, the image rotation system and the light splitting prism are positioned on the main optical path in order, the light composition prism is cooperated with an OLED display apparatus, an OLED display surface and an image intensifier fiber panel position are in conjugation, the OLED display surface and an image intensifier image plane are combined to a main channel of a sighting telescope, and the CCD relay system and the light splitting prism are in cooperation. Apart from a sighting function of a common sighting telescope, the sighting telescope also has functions of television shooting, video image and aiming partition superposition, transmission of an acquired video to a line concentration controller in a wireless transmission mode, display of the video through a display apparatus and the like, and interoperability and cooperation capability between users are effectively raised.
Owner:HENAN COSTAR GRP CO LTD
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