258results about "Hyaluronic acid adhesives" patented technology

A solid surface material with an antimicrobial agent in a thermoset and / or thermoplastic resin matrix where the antimicrobial agent comprises a chitosan-metal complex.

The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and / or copolymers, the formation of resins and blends, and the reconstitution of polymer and / or copolymer solutions, and the dissolution and blending of “functional additives” and / or various polymers and / or copolymers to form advanced composite materials.

A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.

A solid surface material with an antimicrobial agent in a thermoset and / or thermoplastic resin matrix where the antimicrobial agent comprises a chitosan-metal complex.

Water-based, substrate treatment compositions contain (A) at least one chitosan selected from chitosan and a chitosan derivative, and (B) a metal compound containing at least one metal selected from Ti, Zr, Hf, Mo, W, Se, Ce, Fe, Cu, Zn, V and trivalent Cr. In particular, the water-based, substrate treatment compositions can improve the interlayer adhesion between metal materials and resin coating layers such as films or coatings, and can also improve the corrosion resistance and solvent resistance of such metal materials.

The invention relates to an adhesive used for an artificial board and a preparation method thereof. The invention is characterized in that the artificial board consists of water, acid, chitosan, phenol and enzyme; the detail steps of the preparation technique are as follows: 70 to 100 portions of water, 0.01 to 6 portions of acid and 0.01 to 12 portions of flexible components are added into a stainless steel kettle; the temperature is between 10 and 80 DEG C; a stirring machine is started for uniformly mixing at a speed of 400r / min; 0.01 to 45 portions of phenol are added for stirring; the pH is adjusted to be 3 to 8; 1 to 10 portions of enzyme is added for continuously stirring; enzyme treatment time is between 0.1 minute and 48 hours; after the viscidity of the adhesive is 4 cups for 20 to 100 seconds, stirring is stopped; and then an opening is sealed for storage. The adhesive used for the artificial board does not contain formaldehyde, has no poison and smells during the production and use processes, does not release harmless gases, is safe and environmental friendly; the used chitosan is natural product which can be decomposed and recycled; in the invention, biocatalysis and biological transformation technologies are applied to wood industry; and bio-enzyme catalytic polymerization is adopted for preparing the adhesive and can be carried out under normal temperature and pressure.

The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.

The invention provides a preparation method of a highly stable hydrophilic coating for the surface of a medical device. The method comprises (1) a step of polishing, washing and drying the surface ofa medical instrument substrate; (2) a step of preparing an adhesive layer, namely a step of dissolving a compound containing a catechol component and a polyamino compound into a Tris-HCl buffer solution having a concentration of 0.05M and pH of 8.5 in a mass ratio of 1-2:1, and preparing the adhesive layer on the substrate; (3) a step of hydrophilic coating preparation, namely a step of dissolvinga zwitterionic polymer containing a dopamine group component into a Tris-HCl buffer solution having a concentration of 0.05M and pH of 8.5, and preparing a hydrophilic coating on the substrate. The method is simple to operate, mild in conditions and universal. The prepared hydrophilic coating has super hydrophilicity, good biocompatibility, anticoagulant properties, and high stability, and has good application prospect in the field of medical devices.