The invention relates to the technical fields of a traditional Chinese medicine and a preparation method thereof, and concretely relates to a pillow core formula of a health-caring health-preserving drug pillow. The pillow core formula is composed of Taihang aged thuja sutchuenensis, Taihang spine jujube kernel, Huai flos chrysanthemum, Huai pearl chrysanthemum, ginseng, amber, fleeceflower stem,polygala root, pearl shell, dahurian angelica root, pseudo-ginseng, borneol, mint, keel, Chinese angelica, Ligusticum wallichii, aquilaria wood powder, cassia seed, buckwheat husk, wick, sophora flower, silktree flower, lavender, lily, sweet osmanthus, jasmine, magnolia flower, lotus plumule, lotus, honeysuckle flower, rose flower, mulberry leaf, and safflower. The pillow core has the following advantages of tonifying brain and tranquillizing, activating veins and activating collaterals, adjusting qi and blood, clearing liver and bladder, resisting bacteria and killing insects, clearing heat and detoxifying, dispelling wind and dispelling cold, and strengthening physique; and has obvious curative effects for illness such as dizziness, insomnia, dreaminess and irritability due to cervical spondylopathy.