The invention relates to the technical field of traditional Chinese medicine, in particular to a drug for treating chronic bronchitis, which can solve the problems of high cost and non-significant efficacy of Chinese and western drugs which are adopted currently. The drug is prepared by Indian buead, common yam rhizome, malaytea scurfpea fruit, epimedium herb, tatarian aster root, common coltsfoot flower, sweet apricot seed, perilla fruit, membranous milkvetch root, largehead atractylodes rhizome and tangerine peel, and the preparation method comprises the following steps: mixing the Indian buead with the common yam rhizome, dividing into four part, mixing the first part with the malaytea scurfpea fruit and the epimedium herb, and adding brine for soaking; mixing the second part with the tatarian aster root and the common coltsfoot flower, and adding white spirit for soaking; mixing the third part with the sweet apricot seed and the perilla fruit, and adding urine of boys under 12 for soaking; and mixing the fourth part with the membranous milkvetch root, the largehead atractylodes rhizome and the tangerine peel, adding ginger juice for soaking, taking out medicines, filtering out juice, then soaking in rice water, then fishing out, sun drying or drying, further using hydromel for mixing, stir-frying till yellow in a pot and smashing. The formula not only has the functions of strengthening vital qi and enhancing body resistance, but also has the effects of reliving cough, eliminating phlegm and relieving asthma; furthermore, the formula has the advantages of capability of treating both manifestation and root cause of the disease, mild nature, no toxicity or side effects, high efficacy, low cost and a wide range of applications.