32 results about "Pituitary tumours" patented technology

The invention discloses a medicament for treating hypophysis cancer, which is prepared from fleece-flower root, sophora bud, Dendrobium nobile, polyporus umbellatus, dodder seed, Chinese honeylocust abnormal fruit, apiary and pangolin by a predetermined weight proportions. The medicament can be prepared into any of the conventional oral administration dosage forms.

The invention discloses the use of hordenine in the preparation of drugs for treating pituitary tumors, and relates to the technical field of biopharmaceuticals. Specifically, in this application, the inventors have discovered that hordenine can inhibit TLR4 / NF-κB / The MAPK signaling pathway helps to treat prolactinoma and adrenocorticotropic adenoma to play a drug effect, and solves the plight of drug shortage for patients with prolactinoma and adrenocorticotropic adenoma.

The invention discloses a method for grading pituitary tumor texture images based on fine-grained medical image segmentation and true value discovery data amplification, comprising the following steps: Step 1: medical image segmentation based on fine-grained optimization of Drosophila-density peak clustering; Step 2: Amplification of pituitary tumor data based on true value discovery; Step 3: Grading of pituitary tumor texture images based on Step 1 and Step 2. The present invention accurately segments medical images through the fusion of fine-grained partitioning algorithm and FOA-DPC algorithm; the present invention also realizes medical image data amplification based on truth discovery theory, and solves the problem of too few available medical image data sets. The invention combines the KFOA‑DPC segmentation algorithm with deep learning to solve the problem of dicom format images with complex gray levels and difficult feature extraction, realize the soft and tough classification of pituitary tumors, and assist clinical diagnosis.

The polypeptides in the present invention possess the effects of promoting and inhibiting the secretion of prolactin, and are thus useful as drugs for the prevention and treatment of various diseases, in terms of prolactin secretion stimulants, which are associated with the secretion of prolactin, such as hypoovarianism, spermatic underdevelopment, menopausal symptoms, hypothyroidism, etc. The polypeptides are useful as drugs for the prevention and treatment of various diseases, in terms of prolactin secretion inhibitors, which are associated with the secretion of prolactin, such as pituitary tumor, diencephalon tumor, menstrual disorder, autoimmune diseases, prolactinoma, sterility, impotence, amenorrhea, lactorrhea, acromegaly, Chiari-Frommel syndrome, Argonz-del Castilo syndrome, Forbes-Albright syndrome, lymphoma, Sheehan's syndrome, spermatogenesis disorder, etc.

The invention discloses a pituitary tumour cutting and clearing-away device. The pituitary tumour cutting and clearing-away device comprises an external clearing-way machine, a drainage tube and a sucking mechanism, wherein the external clearing-away machine is connected to the drainage tube; a negative-pressure suction machine is started; the drainage tube is used for guiding and draining pituitary tumours into a tumour substance collecting box; a sucking head sucks pituitary tumours; after last-time sucking is finished, the sucking tube is pulled upwards, so that extrusion force, on elastictelescopic plates at two sides, of the sucking tube disappears, the elastic telescopic plates at the two sides are shrunk to be closed in a contact mode, and therefore, the drainage tube is preventedfrom generating reflow to make sucked pituitary tumours flow back, the sucking head is prevented from being exposed in air for a long term to be infected with bacteria, and possibility of bacterial infection in operation is reduced; when the sucking mechanism is used again, the sucking tube is downwards extruded, so that two side walls of the sucking tube cling to the elastic telescopic plates, and the sucking head passes through a tube orifice to suck the pituitary tumours; the sucking head adopts a flat tube body, and the inner cavity of the sucking head is gradually reduced from back to front, and a formed liquid knife is more sharp, so that practicability of the device is improved.

The invention provides a non-functional pituitary adenoma detection device and its application. The device of the present invention performs Massarray SNP typing detection on the single nucleotide polymorphism site rs2981582 of the sample to be tested. This site has a significant correlation with the pathogenesis of non-functioning pituitary tumors. The different genetic models of this locus can provide a certain basis for the diagnosis of non-functioning pituitary tumors and have high clinical value. The invention can provide a simple and reliable diagnostic method for the early diagnosis of patients with non-functional pituitary tumors.

The invention provides a non-functional pituitary adenoma detection device and its application. The device of the present invention performs Massarray SNP typing detection on the single nucleotide polymorphism site rs2910200 of the sample to be tested. This site has a significant correlation with the pathogenesis of non-functioning pituitary tumors. The different genetic models of this locus can provide a certain basis for the diagnosis of non-functioning pituitary tumors and have high clinical value. The invention can provide a simple and reliable diagnostic method for the early diagnosis of patients with non-functional pituitary tumors.