53 results about "Pancreatic Fluid" patented technology

One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml / g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.

The invention provides a duodenal internal covering membrane, which is made of degradable shape memory biocompatible material and relates to degradable medical equipment internally installed in a digestive tract. After the internal covering membrane is implanted into a duodenum, chyme can be split from bile and pancreatic juice, so stomach exudates are prevented from being directly digested, absorbed and metabolized in the duodenum, and the histocompatibility is good; after being implanted into a human body, the duodenal internal covering membrane is steady, is not easy to slide off to be incarcerated and can be gradually degraded in the human body after 2 months to 5 years, so complicated operation and the injury to organs and tissue, which are caused when the duodenal internal covering membrane is removed from the human body in the future, are avoided, a rebound effect achieved after the original barrier is instantaneously and thoroughly dismounted can be slowed down, and the duodenal internal covering membrane can be prepared into medical equipment which is used for curing obesity and diabetes mellitus and does not need to be removed from the human body in the future; and tube-shaped part sinking induced by gastrointestinal motility and jejunum content backflow caused by the decrease of a gap between a tube-shaped part of the internal covering membrane and the inner wall of the duodenum can be avoided. The prepared medical equipment for curing the obesity and the diabetes mellitus can achieve the effects of dropping prevention, removal exemption, rebound inhibition and injury reduction.

A fluorescent probe for detecting pancreatic fluid containing a compound or salt thereof represented by formula (I) below.(In the formula, A represents an amino acid residue or N-substituted amino acid residue, with A forming an amide bond with the adjacent NH in the formula; R1 represents a hydrogen atom or 1 to 4 same or different substituent groups that bond with a benzene ring; R2, R3, R4, R5, R6, and R7 each independently represent a hydrogen atom, a hydroxyl group, an alkyl group, or a halogen atom; R8 and R9 each independently represent a hydrogen atom or an alkyl group; and X represents a C1-C3 alkylene group).

The invention discloses an integrated drainage tube for pancreatic duct support drainage and peripancreatic drainage, which includes a bile intestinal fluid drainage tube, a pancreatic juice drainage tube and a ventilation tube. The drainage tube, the pancreatic juice drainage tube includes the integrated pancreatic juice drainage tube, the pancreatic juice drainage connecting tube and the pancreatic juice drainage tube, the drainage tube and the pancreatic juice drainage tube are bifurcated, and the ventilation tube includes the integrated ventilation tube , Ventilation connecting pipe and venting external pipe. The invention can timely drain the intestinal juice, bile and other liquids accumulated around the pancreaticojejunostomy, even once the pancreatic juice leaks out, so that there is no fluid accumulation near the pancreaticojejunostomy, providing good conditions for the early healing of the pancreaticojejunostomy.

The purpose of the present invention is to provide a method whereby it is possible to promptly diagnose the type of pancreatic tumor. Specifically, the present invention pertains to an examination method for determining the type of pancreatic tumor. Said method detects, in the pancreatic fluid sample from a subject, the degree of methylation in a 5'-untranslated region or a region containing a coding region and the 5'-untranslated region of a gene coding mucin core protein, and uses the degree of methylation as an index to classify the pancreatic tumor into a type of pancreatic tumor selected from among pancreatic cancer, gastric type of intraductal papillary mucinous neoplasm, intestinal type of intraductal papillary mucinous neoplasm, and pancreaticobillary type of intraductal papillary mucinous neoplasm.

The present invention relates to a pharmaceutical composition in which a core is microparticles containing predetermined amounts of pancreatin, cetanol, and poloxamer 407, a method for producing the same, and production of water-based enteric-coated microparticles. In addition, the resulting oral dosage form does not contain residual acetone. The technical result is that the core and the enteric-coated microparticles each achieve high stability while maintaining good solubility of the enteric-coated microparticles, which makes it possible for the claimed pancreatin microparticles to be used in the preparation of safe and non-toxic medicaments for the treatment of digestive system disorders.

The present invention is directed to a method for identifying ductal leaks during pancreobiliary surgery in a human patient. The invention comprises the steps of: administering to a human patient undergoing pancreobiliary surgery an effective amount of a pharmaceutical composition comprising secretin and a pharmaceutically acceptable carrier; and observing the patient during the surgery for the presence of pancreobiliary ductal leaks.

The invention discloses a pancreatic juice developer, and a preparation method and an application thereof. The pancreatic juice developer comprises 0.03-0.70g / L of bromothymol blue sodium salt, 0.03-0.70g / L of phenol red sodium salt and 1.23-11.76g / L of sodium bisulfate monobydrate. Compared with pancreatic juice developers in the prior art, the pancreatic juice developer has the advantages of high chromogenic sensitivity and obvious color contrast in the intraoperative seepage detection process. The pancreatic juice developer can flexibly realize pancreatic juice visualization in the intraoperative and postoperative processes according to concrete demands by preparing different dosage forms and selecting carriers in order to accurately realize qualitative diagnosis and intraoperative positioning diagnosis of pancreatic fistula.