34 results about "Oral Microflora" patented technology

The present invention discloses an oral composition comprising a combination of probiotic bacteria selected from the group comprising Streptococcus, Eubacterium, Neisseria, Veillonella and pH-rising and / or buffering components, which re-establishes an oral microflora associated with good oral health in subjects with a disturbed oral microflora. The invention also discloses the use of the oral composition in combination with other oral health promoting products to help subjects suffering from disorders such as oral dryness, caries, halitosis, inflamed oral mucous membranes or oral fungal infections to restore good oral health.

Oral compositions, which are preferably chewable compositions, containing a peroxide source and a peroxide decomposition catalyst in a contactless manner liberate molecular oxygen in the oral cavity upon use by catalyzed decomposition of the peroxide source. The oral composition promotes oral health by providing a more aerobic environment for oral flora.

A lactic bacteria strain that is exogenous to the oral microflora is selected for its ability to adhere the pellicle of the teeth and to produce a growth inhibition factor. This strain is used for the preparation of a composition intended for reducing dental plaque and for treating or preventing root caries and other diseases related to Actinomyces naeslundii in mammals.

The invention discloses lactobacillus plantarum with an effect of preventing and treating decayed teeth, which belongs to the technical field of microorganisms. According to the invention, a rat decayed tooth model is established; the serum biochemical indexes, oral flora, tooth demineralization and decayed tooth conditions of mice in a blank control group, a model group, an intervention group anda prevention group are compared, the lactobacillus plantarum is determined that the lactobacillus plantarum CCFM8724 has the effect of preventing and treating decayed teeth, the application effect ofthe lactobacillus plantarum CCFM8724 is superior to that of a traditional anti-caries drug chlorhexidine, and the lactobacillus plantarum CCFM8724 has broad market application prospects. Meanwhile, the lactobacillus plantarum CCFM8724 can be applied to probiotic functional foods and daily chemical products such as bacterial powder, yoghourt, chewable tablets, chewing gum, toothpaste and mouthwash, and is expected to open a new functional market for preventing and treating decayed teeth by probiotics.

The invention discloses a probiotic composition for improving health of the oral cavity. The composition comprises yeast, lactobacillus helveticus, lactobacillus rhamnosus and bifidobacterium longum;and the viable count of each gram of the composition is 5 billion CFU, wherein the viable count of the yeast is 5.2 hundred million CFU, the viable count of the lactobacillus helveticus is 2.68 billion CFU, the viable count of the lactobacillus rhamnosus is 1.44 billion CFU, and the viable count of the bifidobacterium longum is 3.6 hundred million CFU. Probiotic raw materials selected for the probiotic composition for improving health of the oral cavity disclosed by the invention are food raw materials, so that the product namely the probiotic composition can be directly eaten and is safe to eat. After being eaten, the probiotic composition can complete operation of regulating the balance of the microbial population of the oral cavity, can improve microbial population of intestinal tracts,and can further solve the problems of the health of the oral cavity, such as halitosis caused by the problems of the health of the intestinal tracts.

The invention discloses an application of lactobacillus paracasei L9 to prevention or treatment oral disease and regulation of oral cavity flora. L9 can be used for preparing a medical composition anda food for preventing or treating dental caries. Research proves that L9 can notably relieve generation degree of occlusal surface E-level dental caries, after the LP is taken, the structure of the oral cavity flora is changed notably, particularly actinobacteria is notably increased, the actinobacteria of L9 group is obviously reduced, klebsiella, aerococcus, Gemella, corynebacterium and pseudomonas aeruginosa on the classification level are notably reduced, and the oral disease risk is reduced. When L9 is taken, the saliva species richness is notably reduced, the relative abundance of oraldisease relevant fungi of streptococcus salivarius, actinomycetaceae, peptostreptococcus and the like is notably reduced, and the L9 can have relieving effects on periodonitis diseases. The dental plaque flora species diversity is notably reduced, the relative abundance of leptothrix, fusobacteriaceaeand flavobacterium is notably reduced, and the L9 can have relieving effects on oral diseases of periodontal disease, halitosis, dental caries and the like.

The invention provides an effervescent tablet for mouthwash. The effervescent tablet has effects of promoting oral cleaning, maintaining oral flora balance, repairing oral mucosal injury and inflammation and effectively preventing oral diseases. The effervescent tablet contains 5-20 parts of compound probiotics, 0.01-0.5 part of sodium azulene sulfonate, 0-0.5 part of mint and 79-95 parts of effervescent component. The effervescent tablet is prepared by uniformly mixing the components and tabletting by adopting a conventional method. The effervescent tablet is cool, refreshing and analgesic, can effectively repair oral mucosal injury, has an obvious anti-impact effect on oral inflammation, can effectively supplement oral probiotics, promotes oral flora balance, can effectively inhibit propagation and growth of oral pathogenic bacteria, and has positive significance for oral health.

The invention relates to the technical field of daily chemical products, in particular to a composition with an oral cavity health care function and a preparing method and application thereof. The composition comprises glycyrrhetinic acid, a herba taraxaci extract, totarol and a krameria triandra extract. According to the composition, different medicinal mechanisms of various components are utilized, the glycyrrhetinic acid, the herba taraxaci extract and the totarol are compounded and further supplemented with the krameria triandra extract, and thus full is given to the synergistic effects ofall the components. In the meanwhile, effective components which are hard to dissolve, disperse and absorb are subjected to nanocrystallization, so that the absorptivity and bioavailability of the components by the mouth mucosa are significantly increased, and it is guaranteed that the effective components play a synergistic effect to the greatest extent. The obtained composition has the functions of inhibiting helicobacter pylori and other bacteria harmless to the oral cavity, maintaining the balance of the flora of the oral cavity, and preventing and relieving gingival bleeding, gingivitisand inflammations of the oral cavity; meanwhile, the composition has the advantages of being natural in raw material, wide in source, safe to the human body, low in cost, convenient to produce and thelike.

The present invention provides an oral care composition comprising a carboxylic acid of the formula (I) wherein: R1 is H, or is a substituted or unsubstituted alkyl group; and R2 is H, OH, or NH2; for use in: (a) selectively promoting, in an oral cavity: growth, metabolic activity or colonization of bacteria that have beneficial effects on oral health, relative to growth, metabolic activity or colonization of pathogenic oral bacteria; (b) selectively promoting, in an oral cavity, biofilm formation by bacteria that have beneficial effects on oral health, relative to biofilm formation by pathogenic oral bacteria; or (c) maintaining and / or re-establishing a healthy oral microflora.

The invention relates to mouthwash containing traditional Chinese medicine prebiotics and a preparation method of the mouthwash containing traditional Chinese medicine prebiotics. Through a large number of researches, 'water extraction and alcohol precipitation' waste of traditional Chinese medicines is subjected to biological, chemical and physical treatment to prepare the traditional Chinese medicine prebiotics, and the traditional Chinese medicine prebiotics are added into the mouthwash, so that on one hand, oral flora can be remarkably improved, decayed teeth can be prevented, and on the other hand, the purpose of utilizing the 'water extraction and alcohol precipitation' waste of the traditional Chinese medicines can be achieved; and therefore, the production cost is effectively reduced, the economic benefit is improved, besides, the damage of water extraction and alcohol precipitation waste to the environment can be reduced, and great market prospects and social significance are achieved.

The invention provides oral helicobacter pylori-resistant turmeric bacteriostatic toothpaste, and relates to the technical field of daily necessities. The oral helicobacter pylori-resistant turmeric bacteriostatic toothpaste is prepared from the following raw materials in parts by weight: 3 to 8 parts of sorbitol, 2 to 5 parts of hydrated silica, 20 to 30 parts of water, 3 to 8 parts of polyethylene glycol, 1 to 3 parts of saccharin sodium, 1 to 3 parts of trisodium phosphate, 5 to 10 parts of chlorhexidine acetate, 2 to 5 parts of lactoferrin, 2 to 5 parts of licorice extract, 1 to 3 parts of essence, 3 to 8 parts of lactobacillus reuteri and 3 to 8 parts of curcumin. The oral helicobacter pylori-resistant turmeric bacteriostatic toothpaste provided by the invention has the effect of resisting helicobacter pylori and most harmful germs, can diminish inflammation and maintain oral flora balance, plays an anticancer effect to a certain extent, and can regulate the immune system of a human body and hinder the spread of germs.

The invention relates to a method for preparing traditional Chinese medicine prebiotic toothpaste from water extraction and alcohol precipitation waste and application of the traditional Chinese medicine prebiotic toothpaste. Through a lot of researches, traditional Chinese medicine water extraction and alcohol precipitation waste is subjected to biological, chemical and physical treatment to prepare traditional Chinese medicine prebiotics, and the traditional Chinese medicine prebiotics are added into the toothpaste, so that oral flora can be remarkably improved, and decayed teeth can be prevented; moreover, the purpose of utilizing traditional Chinese medicine water extraction and alcohol precipitation waste can be achieved, thereby effectively reducing the production cost and enhancing economic returns; the damage of water extraction and alcohol precipitation waste to the environment can be reduced, and the method has great market prospects and social significance.

The invention relates to a Chinese herbal medicine plant oral care composition, and a preparation method and an application method thereof. The composition is prepared from the following raw materials: sorbitol, hydrated silica, water, polyethylene glycol-8, sodium lauryl sulfate, essence, a Chinese herbal medicine extract, methyl hydroxybenzoate, cellulose gum, CI77891, sodium saccharin, tetrasodium pyrophosphate, and zinc citrate. The ingredients of the above Chinese herbal medicine extract are prepared from the following raw materials: pubescent holly root, rhizoma anemarrhenae, Chinese angelica, pseudo-ginseng, cortex moutan, gentiana macrophylla, rhzizoma drynariae, cortex lycii radicis, sarcandra glabra, and Chamaemelum nobile. The preparation process of the invention is simple. Since the Chinese herbal medicine extract contains various natural plant organic acids, trace elements, minerals, chlorogenic acid and flavonoids compounds, the Chinese herbal medicine plant oral care composition has antibacterial, antiviral, anti-inflammatory and free radical removal effects, and can effectively inhibit harmful bacteria, cultivate beneficial flora, condition and repair oral microflora micro-ecological balance and fundamentally reduce and prevent and treat various oral problems if being used for a long time.

A lactic bacteria strain that is exogenous to the oral microflora is selected for its ability to adhere the pellicle of the teeth and to produce a growth inhibition factor. This strain is used for the preparation of a composition intended for reducing dental plaque and for treating or preventing root caries and other diseases related to Actinomyces naeslundii in mammals.

The invention discloses mouthwash for balancing oral flora. The mouthwash comprises the following raw materials by weight percentage: 1-1.5% of a chitosan / sodium copper chlorophyllin compound, 0.4-0.6% of catechinic acid, 2-3% of beta-cyclodextrin, 3-5% of a surfactant, 5-8% of xylitol, 0.8-1.2% of essence, 10-15% of a humectant, 15-25% of ethanol, 0.5-2% of a preservative and the balance water. The invention also discloses a preparation method of the mouthwash for balancing oral flora. Through mutual cooperation of all the substances, the mouthwash can balance oral flora and improve the oralecological environment, also can promote oral wound healing, control decayed teeth and refresh breath, and has no toxic or side effect.

The invention discloses oral antibacterial toothpaste and relates to the technical field of daily necessities. The oral antibacterial toothpaste is prepared from following raw materials in parts by weight of 0.05 to 0.3 part of triclosan, 1 to 3 parts of sorbitol, 1 to 3 parts of menthol, 3 to 5 parts of hydrated silica, 3 to 5 parts of plant polypeptide, 1 to 3 parts of sodium phytate, 5 to 8 parts of biological lysozyme, 5 to 8 parts of menthol, 5 to 8 parts of honeysuckle flower extract, 3 to 5 parts of glycerol, 1 to 3 parts of bletilla striata extract, 1 to 3 parts of liquorice root extract, 3 to 5 parts of lactobacillus paracasei, 8 to 10 parts of orange peel powder, 8 to 10 parts of sodium lauryl sulfate, 1 to 3 parts of lactoferrin and 1 to 2 parts of essence, and 10-15 parts of purified water. The oral antibacterial toothpaste disclosed by the invention can inhibit harmful bacteria and maintain beneficial bacteria, has antibacterial and refreshing effects, and is capable of regulating oral flora balance, maintaining oral autoimmunity and caring oral health.

The invention relates to the field of biological information technology and medical health, and discloses a concept, thought and method for mining a community functional group based on the network analysis technology, and an FBA functional group found from a healthy human oral flora. The functional group is mainly composed of bacteria of the phylum F, the phylum B and the phylum A of actinobacteria, the whole functional group is of a structure that the phylum F and the phylum B synergistically inhibit the phylum A, and the functional group is generally a module with the most species number and the highest density in a healthy oral cavity network. Specifically, the functional group is composed of two sub-functional groups (Sub-Guld), wherein one of the sub-functional groups is mainly composed of F and B mycophylum bacteria, and the other one of the sub-functional groups is mainly A mycophylum bacteria. Species in the two sub-functional groups are in a synergistic relationship, but the two sub-functional groups are in a complete antagonistic competition relationship. The FBA functional group can effectively reflect the stability of the environment in the oral cavity, and a biological foundation is laid for oral health and oral disease healing condition monitoring.

The invention discloses a Miao medicine tooth strengthening formula for treating periodontitis and a preparation method, and the Miao medicine tooth strengthening formula comprises halite, gypsum, teasel root, melaleuca sativa, parsley, pruritus pruritus, blumea balsamifera, selaginella tamariscina and Chinese fevervine herb. The Miao medicine tooth strengthening formula has good effects of promoting osteoblast proliferation and promoting osteoblast precursor cells to be differentiated into mature osteoblasts, and a stock solution prepared from the Miao medicine tooth strengthening formula is used as a traditional Chinese medicine additive to be prepared into related oral care products. The traditional Chinese medicine composition can be used for solving the problems of oral flora imbalance and large side effects caused by frequent administration of antibacterial medicines or anti-inflammatory medicines. The traditional Chinese medicine composition can be used for treating oral diseases, such as Miao medicine tooth-strengthening formula toothpaste, Miao medicine tooth-strengthening formula mouth wash, Miao medicine tooth-strengthening formula oral sugar and lozenges.

Disclosed are a toothpaste with antibacterial and bacteriostatic effects for adjusting oral flora and a preparation method of toothpaste. The toothpaste comprises the following components in percentage by weight: 16%-35% of an abrasive agent, 10%-25% of a thickening agent, 0.2%-0.6% of a preservative, 2.6%-3.6% of a surfactant, 0.22%-0.38% of a sweetening agent, 22%-37% of a humectant, 0.4%-0.8% of an adhesive, 0.4%-1.7% of a stabilizer, 0.45%-0.8% of a flavoring agent, 5%-12% of hand sanitizer extract, 3%-5% of coconut shell charcoal powder and the balance deionized water. According to the toothpaste disclosed by the invention, by adding the gynura divaricata extract into the components, the gynura divaricata extract is a pure natural plant extract, is very safe to a human body, has antibacterial, bacteriostatic and anti-inflammatory effects, not only has common cleaning and tooth-protecting capabilities, but also has a remarkable inhibition effect on oral bacteria, and is convenient to use.

The invention relates to a modified biological lysozyme composition. The tooth whitening essence is prepared from the following components in parts by weight: 50 to 60 parts of sorbitol, 0.01 to 0.05 part of biological lysozyme, 1 to 2.5 parts of turmeric root extract and 20 to 25 parts of silicon abrasive. The tooth whitening essence can effectively keep oral flora in a balanced state, and especially has a whitening effect on teeth.

The invention relates to the technical field of toothpaste preparation, in particular to helicobacter pylori toothpaste and a preparation method and device thereof.The helicobacter pylori toothpaste is prepared from, by mass, forsythiaside, fagopyrin, tea polyphenol, glycyrrhetinic acid, lactoferrin, hydrated silica, sorbitol, glycerin, purified water, herbal extracts and essence. Comprising a supporting frame, a fixing rod, a connecting ring, a feeding pipe, a blending bag, an abutting assembly, a mixing module and a scraping assembly, the fixing rod is fixedly connected with the supporting frame, the feeding pipe is fixedly connected with the connecting ring, the feeding pipe is communicated with the blending bag, the scraping assembly comprises a sliding rail, a sliding block, a connecting strip and a scraping strip, the sliding rail is fixedly connected with the blending bag, the connecting strip is fixedly connected with the sliding block, and the scraping strip is fixedly connected with the sliding block. The prepared helicobacter pylori toothpaste has the characteristics of diminishing inflammation and maintaining the balance of oral flora, the production of production personnel is facilitated, and the production efficiency is improved.

The invention relates to a gum base composition for protecting the balance of oral flora. The gum-based composition is prepared from a gum base, bioactivity mineral powder and polylysine, wherein a weight proportion of the bioactivity mineral powder and the polylysine is (2 to 25) : (0.0003 to 10). According to the gum base composition disclosed by the invention, the bioactivity mineral powder and the polylysine in the gum base composition are capable of inhibiting and killing various pathogenic bacteria in an oral cavity, preventing and treating oral problems of oral infection, oral ulcer, chronic gingisitis and the like, and have long-acting bacteria resistance; meanwhile, the bioactivity mineral powder and the polylysine have a certain selective protection function on beneficial bacteria in the oral cavity, the balance of flora in the oral cavity can be effectively regulated, and normal sanitation and health of the oral cavity can be maintained. Through remineralization of the bioactivity mineral powder on teeth, the gum base composition is capable of effectively repairing dentin defects; the gum base composition provided by the invention is convenient to use, wide in receiver groups and very strong in market application value.

The invention belongs to the technical field of daily necessities, and particularly relates to toothpaste with antibacterial and bacteriostatic effects and capable of adjusting oral flora and a preparation method of the toothpaste, and the toothpaste comprises a toothpaste body and a toothpaste tube for containing the toothpaste body. The toothpaste tube is squeezed through the two rotating squeezing rods, it is guaranteed that the squeezing rods can roll over the surface of the toothpaste tube, no non-squeezed part exists, it is guaranteed that the remaining toothpaste body in the toothpaste tube can be almost completely squeezed out, waste of the toothpaste body is reduced, and the toothpaste body in the toothpaste tube can be fully utilized; the natural extract is adsorbed in the pore structure of the active carbon, the active carbon can be uniformly dispersed after the active carbon is mixed with other raw materials to prepare the toothpaste, the natural extract in the pores can give full play to the antibacterial activity and desensitization acid-proof activity, and the active carbon has very good stability, so that the natural extract can continuously give play to the antibacterial activity, and the toothpaste can be used for preparing the toothpaste. Therefore, the antibacterial performance, the antibacterial durability and the desensitization acid-proof performance of the toothpaste are greatly improved.

A medicine for treating oral ulcer and a preparation method thereof, the invention relates to the technical field of traditional Chinese medicine. The invention discloses a medicament for treating oral ulcer and a preparation method thereof. The main raw materials of the medicament are asarum, hanging golden lamp, honeysuckle, scutellaria baicalensis, forsythia, astragalus, codonopsis pilosula, angelica, raw land, yam, poria cocos and bupleurum , dogwood, licorice. The medicine of the present invention has a good therapeutic effect on oral cavity microbial flora imbalance and oral odor caused by traumatic ulcers, and oral ulcers caused by virus and bacterial trauma; it can also be used for the treatment of recurrent oral ulcers and lichen planus caused by unknown reasons and autoimmunity. treat.

The invention relates to application of black raspberry lyophilized powder in preparing a drug for inhibiting oral diseases. The black raspberry lyophilized powder or an extract of the powder as an active ingredient is in combination with a pharmaceutically acceptable adjuvant to form a pharmaceutical preparation. The adjuvant comprises, by weight, 83-93% of black raspberry lyophilized powder or the extract, 1-5% of maltodextrin, 2-6% of filler, 1-5% of disintegrant and 1-4% of lubricant. The pharmaceutical preparation has small adjuvant amount, uniform dispersion of active ingredients, good stability and high bioavailability, can effectively inhibit the growth of pathogenic bacteria, maintain the balance of oral flora and further improve generation and development of poor oral breath likeozostomia.

The invention relates to an oral metagenome data analysis method. According to the data analysis method of the invention, an oral microflora of a sjogren syndrome patient is analyzed based on a high-flux sequencing facility; furthermore saliva microbe diversity of the primary sjogren syndrome patient is analyzed based on cluster analysis, diversity index analysis, evolution branch analysis and abundance analysis; the composition difference of the microflora in the oral cavity of the primary sjogren syndrome patient in China is evaluated; the substantial different flora is screened and a treatment guidance is supplied.

The invention relates to an oral traditional Chinese medicine gargle suitable for long-term hospitalization patients with oral infection and dysbacteriosis. The oral traditional Chinese medicine gargle comprises the following components in parts by weight: 10-20 parts of rhodiola rosea, 10-20 parts of gynostemma pentaphylla, 25-35 parts of dandelion, 10-20 parts of mint, 4-8 parts of catechu, 4-8parts of golden cypress, 25-35 parts of sargentgloryvine stem, 10-20 parts of lotus leaves and 4-8 parts of licorice roots. The traditional Chinese medicine gargle can inhibit bacteria, improve oral flora imbalance and relieve oral infection, is safe and non-toxic, can be orally taken for gargling, and is easy to accept in taste.

The invention discloses an oral flora collection device capable of being remotely controlled. The oral flora collection device comprises a machine body and a handle which are connected in a pistol shape; the front end of the machine body is connected with a collecting part through an adjusting rod; a lighting bulb and a camera are arranged at the bottom of the collecting part, and the bottom of the collecting part is further detachably connected with a bacterium taking brush head; a display screen connected with the camera and a screen switch for controlling the display screen are mounted on the machine body; a lighting switch for controlling the lighting bulb and a camera shooting switch for controlling the camera are arranged on the handle; and a power supply device electrically connected with the camera and the display screen is arranged in the handle. The oral flora collection device has the function of visualizing and aseptically replacing the brush head, can realize simple and convenient operation by a single person, overcomes the problems that the existing oral flora collection view field is limited, the brush head is easy to be secondarily infected and the like, and is more beneficial to treatment and nursing of oral diseases.