Application of black raspberry lyophilized powder in preparing drug for inhibiting oral diseases

Abstract

The invention relates to application of black raspberry lyophilized powder in preparing a drug for inhibiting oral diseases. The black raspberry lyophilized powder or an extract of the powder as an active ingredient is in combination with a pharmaceutically acceptable adjuvant to form a pharmaceutical preparation. The adjuvant comprises, by weight, 83-93% of black raspberry lyophilized powder or the extract, 1-5% of maltodextrin, 2-6% of filler, 1-5% of disintegrant and 1-4% of lubricant. The pharmaceutical preparation has small adjuvant amount, uniform dispersion of active ingredients, good stability and high bioavailability, can effectively inhibit the growth of pathogenic bacteria, maintain the balance of oral flora and further improve generation and development of poor oral breath likeozostomia.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an application of black raspberry fruit freeze-dried powder or its extract as an active ingredient in the preparation of drugs for inhibiting oral diseases. Background technique [0002] Black raspberry is a berry of the genus Rosaceae. Studies have confirmed that black raspberry contains a large number of active substances, such as phenolic acids, flavonoids, proanthocyanidins, tannins, styrene, lignans, triterpenes and sterols, etc. These active substances can significantly inhibit the growth of pathogenic bacteria. Growth, promotes the growth of probiotics. [0003] The oral microbial community is an important part of the human microbial community, with a large number, many types (>700 species), and rapid changes in the living environment. In the oral microbial community, resident bacteria such as Streptococcus, Lactobacillus, Prevotella, and Actinomycetes ca...

AI Technical Summary

Problems solved by technology

Problems such as bad breath and bad breath have brought great troubles to modern people's life, work, and social interaction. Although certain measures have been taken, such as mouthwash, spray or chewing gum, they are all temporary solutions, not the root cause, so there is an urgent need to develop A pharmaceutical preparation or health care product that can suppress bad breath and bad breath

[0004] There are no related reports on the use of black raspberry fruit freeze-dried powder or its extracts as active ingredients in halitosis and oral adverse diseases caused by oral flora imbalance

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