52 results about "N-nitrosamine" patented technology

The invention discloses a method for comprehensively detecting N-nitrosamine content in meat products. The method comprises the following steps: weighting crushed meat products; adding acetonitrile, normal hexane and anhydrous magnesium sulfate; whirling, ultrasonically extracting, centrifuging, pouring out supernate, remaining acetonitrile and abandoning normal hexane layer; adopting acetonitrile for repeatedly extracting the meat product for 1-3 times; merging the extracting solution; reducing pressure, steaming till being almost dry; using the acetonitrile for keeping the constant volume; using C18 / PSA powder for purifying the constant volume solution; collecting the supernate, thereby acquiring a to-be-detected sample; using a gas chromatogram series mass spectrometer for detecting the to-be-detected sample, preparing a standard solution and drawing a curve and then calculating a result. The method has the advantages of less time consumption, less interference, strong specificity, high sensitivity, simplicity and convenience in operation, low equipment cost and high accuracy and precision.

The invention relates to an extraction and determination method of N-nitrosamine in a smoke quitting product based on hydrophobic ionic exchange solid phase extraction, and belongs to the technical field of tobacco chemical examination. The extraction method of N-nitrosamine in smoke quitting product based on hydrophobic ionic exchange solid phase extraction, provided by the invention, comprises the following steps of: adding the smoke quitting product into an ammonium acetate solution, the concentration of which is 5-100mmol / L, to be extracted; passing the obtained coarse extraction liquid through an activated HiCapt MCX solid extraction column; and then leaching and eluting the liquid to obtain the N-nitrosamine. The extraction method of N-nitrosamine in smoke quitting product based on hydrophobic ionic exchange solid phase extraction can effectively remove impurities and interferents, shorten the treatment time and improve the accuracy and precision of the determination method. The relative recovery rate of the method is between 92.2% and 108.9%. The within-day precision and the between-day precision are separately smaller than 4.6% and 4.2%.

The invention relates to a 1, 4-nitrosation-N-nitrosamine intermediate (I) compound in the synthesis of alprazolam, a preparation method and application thereof to the preparation of alprazolam. 7-chloro-5-phenylbenzodiazepinone is taken as an initial raw material, and the alprazolam is obtained by the synthesis through certain processes such as condensation ring-closure after a methylamination reaction and an N-nitrosation reaction. Other benzodiazepine derivatives can be synthesized through a 1, 4-nitrosation-N-nitrosamine intermediate obtained by the synthesis. The method has the advantages of unique process, steady product quality, mild process conditions, easy control, and high yield, and can control lower production cost and reduce environmental pollution.

The invention discloses a tobacco leaf pretreatment method during tobacco primary processing. The tobacco leaf pretreatment method comprises the following steps of: performing dispersion and moisture regaining on a tobacco, conveying to digesting equipment for digesting through conveying equipment, wherein temperature of hot water of the digesting equipment is set between 70 and 100 DEG C; digesting the tobacco for 5 to 15 minutes; conveying the tobacco to a draining device for draining; spraying to add a lining; dehumidifying by hot air; and after reducing the water to 22 percent, laying the leaves for 15 to 30 minutes and cutting. In the tobacco leaf pretreatment method, the tobacco is dispersed and subjected to moisture regaining, so that the storage time of the tobacco added with the lining can be reduced, the working efficiency is improved and the time is totally reduced by 100 minutes due to a tobacco digesting mode; furthermore, the cigarette sense smoking quality is improved, the chemical constituents of a cigarette are coordinated, and harmful substances, such as oil tar of smoke, smoke nicotine, CO and N nitrosamine in the cigarette (TSNAs), can be reduced greatly; therefore, the quality of cigarettes is improved.

The invention discloses a sausage quality improver, and the sausage quality improver consists of tea polyphenol, calcium ascorbate and potassium chloride in a mass ratio of 1: (1-2): (10-20). According to the sausage quality improver disclosed by the invention, with the cooperation of the tea polyphenol, the calcium ascorbate and the potassium chloride, generation of nitrosamine in food is blocked, the sausage quality improver has a redox reaction with nitrite, so that the residue of nitrite is reduced; and meanwhile, the tea polyphenol can also inhibit the growth of microorganisms, so that the shelf life of Cantonese style sausage is effectively extended. The invention further provides the Cantonese style sausage into which the quality improver is added, and the Cantonese style sausage has the characteristics of strong fragrance, bright color, pure flavor and the like. The invention further provides a preparation method of the Cantonese style sausage.