Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for quickly detecting volatile N-nitrosamine in cosmetics

A detection method and volatility technology, which is applied in the field of rapid sample processing and detection of volatile N-nitrosamines, can solve problems such as high detection limit and interference, and achieve high accuracy, low cost, and simple pretreatment Effect

Inactive Publication Date: 2017-01-11
ANHUI YIKANGDA PHOTOELECTRIC TECH CO LTD +2
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the method commonly used in GB / T29669-2013 is gas chromatography-mass spectrometry, but this method is easily interfered by other ingredients in cosmetics, and the detection limit is high

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for quickly detecting volatile N-nitrosamine in cosmetics
  • Method for quickly detecting volatile N-nitrosamine in cosmetics
  • Method for quickly detecting volatile N-nitrosamine in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments. But the following embodiments are only limited to explain the present invention, and the protection scope of the present invention should include the entire content of the claims, not only limited to the present embodiment.

[0020] The invention relates to a rapid detection method for volatile N-nitrosamines in cosmetics. The steps are: weighing a small amount of cosmetic samples, adding amine sulfamate and acetone for ultrasonic dissolution, and extracting with dichloromethane layer after refrigerated centrifugation. The quantitative detection of target compounds was realized by gas chromatography-thermal energy analyzer. details as follows:

[0021] 1. Reagents and Materials

[0022] Unless otherwise stated, all reagents used were of analytical grade.

[0023] 1.1N-Nitrosodiethylamine: the purity is greater than 98%;

[0024] 1.2 N-nitro...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for quickly detecting volatile N-nitrosamine in cosmetics. The method comprises the following steps: weighing a small amount of cosmetics; adding ammonium sulfamate and acetone, performing ultrasonic dissolution and refrigerated centrifugation, and extracting with a dichloromethane layer; and performing a gas phase chromatography-thermal energy analyzer method on the extract solution to realize quantitative detection of a target compound. According to the invention, the method can effectively detect out volatile N-nitrosamine in water-soluble or fat-soluble cosmetics, has the advantages of simple pretreatment, little time consumption, low cost and high accuracy, is applicable to actual detection of cosmetics, and can provide a technical method support for detection of volatile N-nitrosamine in cosmetics and production quality control.

Description

technical field [0001] The invention relates to the technical field of chemical instrument detection, in particular to a rapid sample processing and detection method for volatile N-nitrosamines in cosmetics and raw materials. Background technique [0002] N-nitrosamines (NAms) are a kind of nitroso compounds and one of the three major carcinogens recognized in the world. Cosmetics, as daily necessities, will stay on the skin, hair, nails, lips and other parts for a long time, and their safety has attracted much attention. There are a certain amount of precursors of N-nitrosamines such as secondary amines and alkylamines in the raw materials of cosmetics. Therefore, these precursors are very easy to generate N-nitrosamines through nitro reaction during the production, storage and sales of cosmetics. According to the classification of the International Agency for Research on Cancer (IARC), 5 volatile N-nitrosamines commonly found in cosmetics: N-nitrosodiethylamine, N-nitroso...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N30/06G01N30/02
CPCG01N30/06G01N30/02
Inventor 计敏刘华刘勇王贻坤朱灵孙淼张龙吴晓松李志刚
Owner ANHUI YIKANGDA PHOTOELECTRIC TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com