The invention discloses traditional Chinese medicinal grains for treating cholecystitis and a preparation method thereof. The traditional Chinese medicinal grains are prepared from the following raw materials in parts by weight: 10-15 parts of dried tangerine peel, 5-10 parts of fingered citron, 15-20 parts of Chinese yam, 10-15 parts of endothelium corneum gigeriae galli, 12-18 parts of capillary Artemisia, 8-14 parts of pseudo-ginseng, 5-10 parts of cape jasmine root, 16-22 parts of bupleurum,10-15 parts of scutellaria baicalensis, 7-13 parts of costusroot, 5-10 parts of uncinata spikemoss herb, 10-15 parts of corydalis tuber, 5-10 parts of radix curcumae, 9-16 parts of rhizoma cyperi, 12-18 parts of cortex moutan, 15-20 parts of purple-flower sowthistle, 10-15 parts of red peony root, 10-15 parts of abrus cantoniensis hance, 15-20 parts of rabdosia lophanthide, 10-15 parts of flos gentianae stramienae, 5-10 parts of honeysuckle, 18-24 parts of fructus forsythiae, 12-16 parts of salviae miltiorrhizae, 16-22 parts of peach kernel, 10-15 parts of Chinese angelica, 5-10 parts of Chinese date, 8-14 parts of hawthorn root, and 10-15 parts of dahurian patrinia herb. The traditional Chinese medicinal preparation has the functions of soothing liver-gallbladder, clearing heat and drying dampness, managing qi and activating blood, promoting qi circulation to relieve pain, strengthening the spleen and stomach, and harmonizing and purging, is remarkable in curative effect, exact in drug effect, quick in response and short in course of treatment when used for treating acute and chronic liver-gallbladder, can be used for improving the symptom and relieving pains of a patient, does not have toxic or side effect to a human body, prevents relapse after healing, and is low in treatment cost, convenient to administrate and worthy of popularization and application.