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Drug combination for treating chronic cholecystitis and preparation method thereof

A technology for chronic cholecystitis and its composition, which is applied in the field of pharmaceutical composition for treating chronic cholecystitis and its preparation, which can solve the problems of easy recurrence, unacceptable economic burden for patients, unsatisfactory long-term effect, etc., and reduce the number of attacks Effect

Inactive Publication Date: 2010-07-07
BEIJING TIANKE RENXIANG MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the domestic drugs for the treatment of this disease are mostly simple anti-inflammatory drugs. Gentamicin antibiotics can only relieve superficial symptoms, and the curative effect is not ideal. They are prone to relapse after drug withdrawal, and patients have to take drugs for a long time. It is easy to develop drug resistance; surgical treatment is mostly based on direct gallbladder removal, which is not suitable for older patients and patients with other organ diseases, which makes it difficult for patients to accept and the financial burden is too heavy, and the long-term effect is not very ideal ; And the use of Chinese patent medicine treatment, side effects after taking, although the pain of cholecystitis is relieved, adverse reactions such as stomach pain and bloating often occur

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Take the following drug combinations:

[0040] Astragalus 60g Scutellaria baicalensis 90g Frankincense 45g Myrrh 75g

[0041] Angelica dahurica 90g Polygonum cuspidatum 100g Dandelion 60g Forsythia 90g

[0042] Honeysuckle 80g Chenpi 105g Citrus aurantium 60g Poria cocos 130g

[0043] Its preparation method is:

[0044] (1) Crush each medicinal material into coarse powder, mix, add water and decoct 3 times, each time for 1 hour;

[0045] (2) Filtrate the water decoction, combine the filtrate, and let stand for 6 hours;

[0046] (3) The supernatant of (2) was collected by filtration, and concentrated to a thick paste with a thermal measurement relative density of 1.36 at 70°C, and set aside;

[0047] (4) Dried and pulverized the obtained thick paste, added about 146 g of a mixture of starch and dextrin (ratio: 4:1), mixed well, made granules with 75% ethanol, dried, and set aside;

[0048] (5) Press the dry granules into tablets to get ready.

Embodiment 2

[0050] Take the following drug combinations:

[0051] Astragalus 75g Scutellaria baicalensis 110g Frankincense 50g Myrrh 100g

[0052] Angelica dahurica 120g Polygonum cuspidatum 120g Dandelion 80g Forsythia 110g

[0053] Honeysuckle 100g Chenpi 140g Citrus aurantium 80g Poria cocos 170g

[0054] Its preparation method is:

[0055] (1) Crush each medicinal material into coarse powder, mix, add water and decoct 4 times, each time for 1 hour;

[0056] (2) Filtrate the water decoction, combine the filtrate, and let stand for 8 hours;

[0057] (3) The supernatant of (2) was collected by filtration, and concentrated to a thick paste with a thermal measurement relative density of 1.34 at 80°C, and set aside;

[0058] (4) Dry and pulverize the prepared thick paste, add about 186g of starch, mix well, make granules with water, add 1% magnesium stearate, mix well, dry, and set aside;

[0059] (5) Press the dry granules into tablets to get ready.

Embodiment 3

[0061] Take the following drug combinations:

[0062] Astragalus 35g Scutellaria baicalensis 50g Frankincense 40g Myrrh 50g

[0063] Angelica dahurica 60g Polygonum cuspidatum 50g Dandelion 30g Forsythia 70g

[0064] Honeysuckle 60g, tangerine peel 65g, citrus citrus 40g, Poria cocos 80g

[0065] Its preparation method is:

[0066] (1) Crush each medicinal material into coarse powder, mix, add water and decoct twice, each time for 1 hour;

[0067] (2) Filtrate the water decoction, combine the filtrate, and let stand for 4 hours;

[0068] (3) The supernatant of (2) was collected by filtration, and concentrated to a thick paste with a thermal measurement relative density of 1.38 at 60°C, and set aside;

[0069] (4) Dry and pulverize the prepared thick paste, add about 25g of lactose and about 48g of dextrin, make granules with 90% ethanol, dry and set aside;

[0070] (5) Press the dry granules into tablets to get ready.

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PUM

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Abstract

The invention discloses a drug combination for treating chronic cholecystitis and a preparation method thereof, belonging to the field of the Chinese herba preparation technology; the drug combination is formed by astragalus mongholicus, baikal skullcap root, frankincense, myrrh, radix angelicae, polygonum cuspidatum, dandelion, forsythia, honeysuckle, dried orange peel, fructus aurantii and poria cocos Chinese medicinal crops which are prepared into tablets by weight proportion; the drug combination has the functions of soothing liver-gallbladder, clearing heat and dehumidification, and diminishing inflammation and relieving pain, is mainly used for treating chronic cholecystitis; the drug combination is pure Chinese medicine preparation, has non-toxic side effect, clinical symptoms are disappeared rapidly, treats both principle and secondary aspect of disease and has remarkable curative effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a pharmaceutical composition for treating chronic cholecystitis and a preparation method thereof. Background technique [0002] Cholecystitis is divided into acute and chronic, and it is more common clinically, especially in women who are obese, prolific, and about 40 years old. Chronic cholecystitis belongs to the category of hypochondriac pain, gallbladder distension, and jaundice in traditional Chinese medicine. It is a chronic inflammatory disease of the gallbladder, mostly caused by stones, parasites, chronic infection, chemical damage, and repeated persistent attacks of acute cholecystitis, with chronic upper abdominal pain and discomfort, indigestion, etc. as the main manifestations. [0003] The chronic cholecystitis is partly caused by the delay of acute cholecystitis, but most of them have no history of acute attack in the ...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P1/16
Inventor 伍荣林
Owner BEIJING TIANKE RENXIANG MEDICAL SCI TECH
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