The invention relates to a medicine for treating spleen-deficiency diarrhea type IBS (Irritable Bowel Syndrome), which uses Chinese medical herbs as the raw material, and a manufacturing method of the medicine. At present, when the spleen-deficiency diarrhea type IBS is treated by western medicine, no special therapy or drugs can be used, the symptomatic treatment manner is mainly adopted clinically, the untoward effects are various and side effects are larger after long-term use of western medicines, the possibility of relapse is high after drug withdrawal, and the long-term follow-up result is poor. According to the invention, Codonopsis pilosula, atractylodes macrocephala, poria cocos, radix paeoniae alba, Rhizoma Pinellinae Praeparata, Saposhnikovia divaricata, dried tangerine or orange peel, humifuse euphorbia herb, liquorice and cortex albiziae are weighed by proportion, and ground into powder, so as to prepare a conventional medicament for oral use. Traditional Chinese medicines are used for achieving the effect of treating both manifestation and root cause of disease, the total effective rate is 96%, radical treatment is implemented based on pathology; the effect is ideal, side effects are avoided, and pain of patients suffering from the spleen-deficiency diarrhea type IBS can be relieved.