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Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof

A technology for gastrointestinal diseases and a composition is applied in the field of traditional Chinese medicine compositions for the treatment of gastrointestinal diseases and their preparation, which can solve the problems of inconvenience for patients to take, poor preparation technology, incompletely defined compound effective substances, etc., and achieves enhancement of memory, growth of wisdom, Anti-aging effect

Inactive Publication Date: 2020-12-08
北京沃德中医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although the addition and subtraction of Atractylodes Rhizoma Atractylodes Rhizome, Radix Paeoniae Alba, Fangfeng, and Tangerine Peel have been used in clinical treatment of intestinal dysfunction, functional dyspepsia, irritable bowel syndrome and other diseases, but because the effective substances of the compound are not completely clear and the preparation technology is not advanced, In practical application, there are problems such as unstable clinical curative effect and inconvenience for patients to take
These problems have seriously restricted the application effect of the compound

Method used

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  • Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Composition of raw materials (parts by weight): 10 parts of Ganoderma lucidum spores, 7 parts of red Ganoderma lucidum spores, 5 parts of Yunzhi, 5 parts of Cordyceps militaris fruiting body, 7 parts of Hericium erinaceus, 2 parts of Dendrobium officinale, 5 parts of hawthorn, 1 part of sandalwood, 1 part of Cyperus cyperi, 1 part of Chinese cabbage, 1 part of gallinaceous gold, and 1 part of white cardamom.

[0032] The preparation method comprises the following steps:

[0033] S1. Mechanically break the wall of Ganoderma lucidum spores and red Ganoderma lucidum spores, add 60wt% ethanol solution according to the weight of 5 times, extract twice, 0.5h each time; filter the extracts, combine them, and recover the ethanol to contain 0.1g crude drug per ml The supernatant liquid was micro-filtered through a 0.05-0.2 μm inorganic ceramic membrane, and the filtrate was concentrated under reduced pressure to an extract with a relative density of 1.2, which became Ganoderma l...

Embodiment 2

[0042] Composition of raw materials (parts by weight): 20 parts of Ganoderma lucidum spores, 12 parts of red Ganoderma lucidum spores, 10 parts of Yunzhi, 12 parts of Cordyceps militaris fruiting body, 10 parts of Hericium erinaceus, 7 parts of Dendrobium officinale, 12 parts of hawthorn, 5 parts of sandalwood, 3 parts of Cyperus cyperi, 4 parts of Chinese cabbage, 3 parts of gallinaceous gold, and 5 parts of white cardamom.

[0043] The preparation method comprises the following steps:

[0044] S1. Mechanically break the ganoderma spores and red ganoderma spores, add 80wt% ethanol solution according to 10 times the weight, extract 2 times, each time for 2h; filter the extracts, merge, reclaim the ethanol to contain 0.5g crude drug per ml The supernatant is micro-filtered through a 0.05-0.2 μm inorganic ceramic membrane, the filtrate is concentrated under reduced pressure to an extract with a relative density of 1.5, and after drying, it becomes the extract of Ganoderma lucidu...

Embodiment 3

[0053] Composition of raw materials (parts by weight): 12 parts of Ganoderma lucidum spores, 9 parts of red Ganoderma lucidum spores, 6 parts of Yunzhi, 7 parts of Cordyceps militaris fruiting body, 8 parts of Hericium erinaceus, 3 parts of Dendrobium officinale, 7 parts of hawthorn, 2 parts of sandalwood, Cyperus 1.5 parts, womb cabbage 2 parts, gallinaceae 1.5 parts, white cardamom 2 parts.

[0054] The preparation method comprises the following steps:

[0055] S1. Mechanically break the wall of Ganoderma lucidum spores and red Ganoderma lucidum spores, add 65wt% ethanol solution according to the weight of 6 times, extract twice, each time for 1 hour; extracts are filtered, combined, and the ethanol is recovered to contain 0.2g of crude drug per milliliter The supernatant is micro-filtered through a 0.05-0.2 μm inorganic ceramic membrane, the filtrate is concentrated under reduced pressure to an extract with a relative density of 1.25, and after drying, it becomes the extrac...

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Abstract

The invention provides a traditional Chinese medicine composition for treating gastrointestinal diseases. The traditional Chinese medicine composition is prepared from the following raw materials: ganoderma spores, red ganoderma lucidum spores, coriolus versicolor, cordyceps militaris sporocarp, hericium erinaceus, herba dendrobium officinale, crataegi fructus, santali albi lignum, nutgrass galingale rhizome, pakchoi seedling, galli gigerii endothelium corneum and amomi fructus rotundus. The traditional Chinese medicine composition can obviously improve spleen deficiency signs and has a rehabilitation effect; intestinal hyperfunction is obviously antagonized, intestinal function inhibition is improved, and the effect of regulating intestinal functions is achieved; an adjusting effect is achieved on gastrointestinal dysfunction; and the obvious effects of relieving pain, resisting fatigue, resisting anoxia and resisting stress are achieved. Research results show that the composition hasa significant improvement effect on functional gastrointestinal diseases or irritable bowel syndrome, is low in cost and easy to operate, and has a wide application prospect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Functional gastrointestinal diseases (FGIDs) are a group of digestive system diseases that have gastrointestinal symptoms, but no organic diseases or abnormal biochemical structures can be found after examination. Patients often experience symptoms such as loss of appetite, early satiety, abdominal pain, nausea, vomiting, abdominal distension, diarrhea, constipation, and difficulty in defecation. According to the current classification method, it includes 28 kinds of diseases, among which functional dyspepsia (FD), irritable bowel syndrome (IBS) and functional constipation (FC) are the most common. [0003] Functional dyspepsia (FD) refers to clinical symptoms such as epigastric pain or discomfort caus...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/00A61P39/00A61K35/57
CPCA61K35/57A61K36/068A61K36/07A61K36/074A61K36/185A61K36/31A61K36/734A61K36/8905A61K36/8984A61K36/9064A61K2236/15A61K2236/331A61K2236/37A61K2236/39A61K2236/51A61P1/00A61P39/00A61K2300/00
Inventor 何军
Owner 北京沃德中医药研究院
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