33 results about "Indigo carmine" patented technology

Iodine is used in about 80 percent of surgeries in the US to remove some level of microbial load on the skin prior to making an incision. Skin sealants are applied over skin preps to seal the skin and hold any remaining bacteria in place. Iodine produces a characteristic orange-brown color on skin. A skin sealant is provided that has a decolorant that reacts with the iodine found in most skin preps, rendering the skin prep colorless. A skin sealant containing ascorbic acid (vitamin C), Indigo Carmine or Indigo will react with the iodine, thus visually indicating where the skin prep and sealant have been applied and allowing an unobstructed view of the incision.

The invention relates to a method for detecting concentration of nine compound coloring agents in auxiliary materials for reconstituted tobacco. The method comprises the following steps: preparing a mixture mother liquor of nine compound coloring agents, namely, lemon yellow, amaranth, indigo blue, carmine, sunset yellow, allura red, brilliant blue, acid red and erythrosine, and a sample solution; preparing a standard operation solution; and adopting a liquid chromatogram-series triple quadrupole spectrum analyzer for analyzing and detecting the concentration of the nine compound coloring agents in the sample solution. The method provided by the invention is accurate and reliable, is high in sensitivity and is very suitable for the analysis for the nine compound coloring agents in the auxiliary materials for the complex matrix reconstituted tobacco.

A concentrated esmolol formulation is provided that is distinguishable from a diluted form of the concentrated esmolol formulation. In one embodiment, the concentrated esmolol formulation allows identification of the concentrate even after transfer of the concentrate out of a labeled primary container. The concentrated esmolol formulation can include from about 25 to about 1000 mg / ml of esmolol hydrochloride, a buffering agent and a color additive. Any number of color additives may be included such as indocyanine green, phenopheylene, hemoglobin, cyanocobalamine, patent blue, and indigo carmine vitamin B2 and naturally occurring vitamins and minerals. The amount included in the formulation is highly dependent on the color additive selected. The color additive should be included in an amount sufficient to easily distinguish the concentrated esmolol formulation from at least about a 1:4 dilution of the concentrate. Also, a medical product is provided that includes a colored concentrated esmolol housed in a container, and a package housing the container and instructions. The instructions can notify that a color additive has been added to the concentrated esmolol formulation to aid in differentiating it. Additionally a method of allowing easy identification of a concentrated esmolol formulation is provided. The method includes providing a colored concentrated esmolol formulation that has from about 25 to about 1000 mg / ml of esmolol and a color additive.

Carbohydrate detectors employing abiotic fuel cell designs are disclosed. The detectors produce current output using reactions between chemical dyes in alkaline solutions and carbohydrates, such as glucose. A linear relationship between current output of the detector and glucose concentration has been observed. This relationship may be used with measurements of current output when the glucose concentration is unknown to determine the unknown glucose concentration. In certain embodiments, the abiotic detectors may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts (i.e., precious metals or biocatalytic species) for glucose detection Organic dyes, such as methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators.

The invention discloses an indigo carmine colorant as well as a preparation method and applications thereof. A mixed solution of indigo carmine and antioxidants contains 0.1%-1%(weight / volume percent concentration, g / 100ml) of indigo carmine, the antioxidants are selected from one or combinations of ascorbic acid, tea polyphenols and phytic acid, and the amount of addition is 0.05%-0.5%(weight / volume percent concentration, g / 100ml). The indigo carmine colorant has advantages as follows: a product is greatly improved in stability, is easy to use and store, and has a good clinical effect; the safety performance is high, and the clinical risk is low; the operation is simple. A prepared indigo carmine solution can be directly used in clinical treatment, dilution and other additional operations are not required, a clinical operation process is greatly simplified, and defects of a colorant obtained with an immediate preparation and use method in the prior art are solved.

The invention provides an automatic analyzing method for trace trivalent chromium in a water sample. An analyzing instrument comprising a low-pressure pump, a sample inlet valve, a mixer, a reactor, an optical circulating tank, an optical detector, a computer processing system, a sample flow passage, a pushing liquid flow passage, a masking agent flow passage, an oxidation liquid flow passage and a developing liquid flow passage is used. The automatic analyzing method includes the following steps that firstly, a base line is measured; secondly, a spectrogram of the trivalent chromium in the sample is measured; thirdly, a working curve is drawn; fourthly, the peak height value of the spectrogram of the trivalent chromium in the sample is brought into a regression equation of the working curve, and the concentration of the trivalent chromium, to be measured, in the sample is calculated. Pushing liquid is an HNO3 water solution, a masking agent is a mixed water solution of ethylenediaminetetraacetic acid and tween-20, oxidation liquid is mixed liquid of periodate potassium, sodium tripolyphosphate, water and a phosphate buffer, and developing liquid is an indigo carmine water solution. By means of the automatic analyzing method, the trace trivalent chromium in a water sample is directly measured, the analyzing operation is simplified, and the analyzing sensitivity is improved.

The invention discloses a preparation method and an application of a microbial manganese-carbon composite material. The preparation method comprises the following steps of: (1) adding HEPES (hydroxyethyl piperazine ethanesulfonic acid) buffering solution for filtering and sterilizing and MnCl2 into a sterilized culture medium under the aseptic condition, inoculating the culture medium with a manganese oxidizing bacterial solution which grows to the logarithmic phase at an inoculum size of 1%, putting a triangular flask into a swing bed, culturing, centrifuging, collecting a precipitate, removing residual ions on the surface by washing with ultrapure water, and drying; (2) weighing the materials prepared in step (1), mixing the materials with sodium hydroxide serving as an activation agent according to a certain proportion, adding deionized water, stirring so that the materials are completely immersed in the activation agent, drying with a drying box, activating at high temperature, washing with hydrochloric acid until no bubble is generated, washing with deionized water until the raw materials are neutral, drying, and grinding to obtain the composite material. The preparation method of the composite material is practical, is convenient to operate and is suitable for the large-scale production of the composite material. The application of the composite material to the removal of indigo carmine in dyeing waste water finds that the composite material is high in adsorption speed and efficiency and can be widely applied to environmental governance.

A composition for aiding the removal of polyps, in the form of a submucosal injectable formulation, comprising one or more salts of hyaluronic acid, saline solution and indigo carmine, but not including a substance exhibiting an angiotonic effect such as epinephrine, norepinephrine, or isoproterenol is described. Further described are a method for removing a polyp from a mucous membrane, the composition for use in endoscopic procedures and a kit for use in an endoscopic procedure.

The invention discloses a formula for fast measuring ozone in water and a method thereof. The method comprises the following steps of: (1) preparing measuring reagent, respectively weighing 755 parts of sodium dihydrogen phosphate fine powder and 1 part of acid indigo carmine fine powder according to weight ratio, evenly mixing in a mixing cylinder, and sealing and packing according to 0.1g of each bag for later use; (2) firstly performing colorimetric measurement to water sample, adding 12.5mL of water sample to be measured into a cuvette with the diameter of 30mm, adding a bag of the measuring reagent prepared in the step (1) and evenly shaking, taking distilled water as reference, and measuring the absorbency under the condition that the wavelength is 600nm; (3) performing the colorimetric measurement to the water sample again, adding 12.5mL of the water sample to be measured into a measuring reagent and water sample-containing colorimetric bottle in the previous step again and evenly shaking, and measuring the absorbency under the condition that the wavelength is 600nm; and (4) computing the content of the ozone in the water with the formula p=1.071*(A1-2A2) / (0.42*3), wherein p is the concentration (mg / l) of the ozone in the water, A1 is the absorbency measured by the step (2), and the A2 is the absorbency measured by the step (3). The invention has the advantages of being simple in measurement steps, being capable of realizing on-site measurement with an automatic apparatus, and being low in measuring cost.

The invention discloses a DNA (Deoxyribonucleic Acid) electrochemical sensor based on an indigo carmine electrochemical polymer membrane and a preparation method thereof. The DNA electrochemical sensor is a three-electrode system sensor with a working electrode, an auxiliary electrode and a reference electrode, wherein the working electrode is a glassy carbon electrode which is modified by the indigo carmine electrochemical polymer membrane after a 5'-terminal modified amino single-chain probe DNA is covalently fixed. The DNA electrochemical sensor has the characteristics of short response time, low limit of detection, excellent stability and excellent reproducibility.

The invention discloses a novel acid dye, which is composed of the following components in parts by weight: 14-16 parts of methylene blue, 31-33 parts of gentian violet, 23-26 parts of carmine, and indigo carmine 31-33 parts, 13-18 parts of iron ion, 2-5 parts of alginic acid, 10-12 parts of bean sprouts powder, 17-20 parts of fish meal, 11-18 parts of seed liquid, 21-24 parts of arrowroot powder and 9- 10 servings. The invention has the advantages that: the novel acid dye of the technical proposal is naturally odorless, fast in coloring and not easy to fade.

Indirect chromoendoscopy is performed by providing a subject with an orally administered composition which includes indigo carmine dye mixed with polyethylene glycol (PEG). Preferably, the subject ingests at least 160 mg of indigo carmine prior to the endoscopic procedure. This is accomplished by ingesting 1 ml to 6 L of a premixed or reconstituted indigo carmine and PEG composition up to twenty four hours prior to the endoscopic procedure.

Abiotic fuel cell and battery designs employing chemical dyes in alkaline solutions are disclosed. The fuel cells and batteries are capable of harnessing electrical power from various carbohydrates, including, but not limited to, glucose; in an anode design that does not require catalysts or membranes to separate half-cell reaction chambers. In certain embodiments, the abiotic fuel cell or battery designs may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts for glucose oxidation (i.e., precious metals or biocatalytic species). In further embodiments, organic dyes, including but not limited to, methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators. In some embodiments, the fuel cells or batteries are capable of generating power on the order of about tens of mW / cm2 from glucose and / or other types of sugars.

The invention discloses a digestive tract mucosa coloring agent and a preparation method, and relates to the technical field of digestive tract detection. The digestive tract mucosa coloring agent comprises the following raw materials in parts by weight: 85-92 parts of an indigo carmine aqueous solution with the mass fraction of 0.15-0.3% and 8-15 parts of a traditional Chinese medicine extracting solution. The traditional Chinese medicine extracting solution comprises the following raw materials in parts by weight: 20-30 parts of Radix Aucklandiae, 20-30 parts of malt, 20-30 parts of Fructus Litseae, 20-30 parts of Radix Linderae, 12-20 parts of Pericarpium Citri Reticulatae, 12-20 parts of Rhizoma Dioscoreae, 12-20 parts of Rhizoma Polygonati, 8-15 parts of Flos Caryophylli, 8-15 parts of Radix Angelicae Sinensis, 8-15 parts of Fructus Jujubae and 8-15 parts of Radix Glycyrrhizae. The coloring agent is further added with the traditional Chinese medicine extracting solution ingredients; the traditional Chinese medicine extracting solution has effects of promoting circulation of qi and stopping pain, invigorating the spleen and reinforcing the stomach, and promoting blood circulation and resisting bacteria; pain of a patient can be reduced; spasm of a digestive tract is reduced; clear color development is facilitated; and the digestive tract mucosa coloring agent has healthcare effect on the intestines and stomach of the patient.

Process for preparing disodium 5,5′-indigosulfonate, the feedstock being indigo, this process including the following steps: i) the indigo is subjected to a sulfonation treatment resulting in a mixture that contains 5,5′-indigosulfonic acid, this process including: ii) a reduction treatment is applied to the mixture obtained in step i), and optionally a purification step, so as to obtain a composition including leuco-5,5′-indigosulfonic acid, iii) the leuco-5,5′-indigosulfonic acid is isolated from the composition resulting from step ii), iv) the leuco-5,5′-indigosulfonic acid resulting from step iii) is oxidized to give disodium 5,5′-indigosulfonate.

The invention discloses an indigo carmine mucosa dyeing agent which is characterized by consisting of the following components in unit g / ml: indigo carmine with the concentration of 0.15%-1.0% and thebalance of water. The indigo carmine mucosa dyeing agent is high in stability, free of other auxiliary materials, high in security and beneficial to long-term preservation.

Process for preparing disodium 5,5′-indigosulfonate, the feedstock being indigo, this process including the following steps: i) the indigo is subjected to a sulfonation treatment resulting in a mixture that contains 5,5′-indigosulfonic acid, this process including: ii) a reduction treatment is applied to the mixture obtained in step i), and optionally a purification step, so as to obtain a composition including leuco-5,5′-indigosulfonic acid, iii) the leuco-5,5′-indigosulfonic acid is isolated from the composition resulting from step ii), iv) the leuco-5,5′-indigosulfonic acid resulting from step iii) is oxidized to give disodium 5,5′-indigosulfonate.

The invention discloses a novel acid dye. The novel acid dye is prepared from the following components in parts by weight: 14 to 16 parts of methyl blue, 31 to 33 parts of gentian violet, 23 to 26 parts of magenta, 31 to 33 parts of Indigo carmine, 13 to 18 parts of iron ion, 2 to 5 parts of alginate, 10 to 12 parts of bean sprout powder, 17 to 20 parts of fish meal, 11 to 18 parts of seed fermentation broth, 21 to 24 parts of radix puerariae powder and 9 to 10 parts of herba houttuyniae. The novel acid dye disclosed by the invention has the advantages of natural property, no odor, fast coloring and low possibility of fading.

The invention discloses a novel mild dye, which consists of the following components in parts by weight: 14-16 parts of basic fuchsin, 23-26 parts of safranin, 23-26 parts of carmine, 31-33 parts of indigo magenta, 13-18 parts of iron ion, 2-5 parts of alginic acid, 10-12 parts of bean sprouts powder, 17-20 parts of fish meal, 11-18 parts of seed liquid, 21-24 parts of arrowroot powder and Houttuynia cordata 9‑10 servings. The invention has the advantages that: the novel soft dye of the technical proposal has no peculiar smell naturally, fast coloring and not easy to fade.

The invention discloses a method for rapidly distinguishing normal tea and suspicious tea. According to the method of the invention, acidic indigo carmine is used as an indicator, and potassium permanganate is used an oxidant; quantitative potassium permanganate preferentially reacts with reducing substances in an extracting solution; although the extracting solution contains other reducing substances except tea polyphenol, the total content of the other reducing substances is far less than that of the tea polyphenol; and meanwhile, facts prove that the other reducing substances in the extracting solution do not have too much influence on a distinguishing result. Compared with a national standard method, the normal tea and the suspicious tea can be distinguished rapidly, a reliable basis is provided for market quality inspection, and the method is simple to operate and easy to implement.

An ophthalmic composition comprising indigo carmine or indigo carmine and trypan blue for identifying intraocular structures and membranes within the eye, and methods of delivering and using the ophthalmic composition for surgical treatment of the eye, including glaucoma and cataract surgery.

A silicate-coated body contains: a mica particle; a first silicate coating at least part of the mica particle; and an ionic organic colorant adsorbed to the first silicate. The ionic organic colorant includes at least one selected from the group consisting of amaranth, new coccine, phloxine B, rose bengal, acid red, fast green, indigo carmine, lithol rubine B, and lithol rubine BCA.

Abiotic fuel cell and battery designs employing chemical dyes in alkaline solutions are disclosed. The fuel cells and batteries are capable of harnessing electrical power from various carbohydrates, including, but not limited to, glucose; in an anode design that does not require catalysts or membranes to separate half-cell reaction chambers. In certain embodiments, the abiotic fuel cell or battery designs may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts for glucose oxidation (i.e., precious metals or biocatalytic species). In further embodiments, organic dyes, including but not limited to, methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators. In some embodiments, the fuel cells or batteries are capable of generating power on the order of about tens of mW / cm2 from glucose and / or other types of sugars.

The invention provides a production apparatus for the synthetic pigment indigo carmine. The production apparatus mainly comprises a storage tank 1 (F101), a storage tank 2 (F102), a storage tank 3 (F103), a reaction vessel (D101), a condenser (C101) and a storage tank 4 (F104), wherein the storage tank 1 (F101) is connected with the reaction vessel (D101); the storage tank 2 (F102) is connected with the reaction vessel (D101); the storage tank 3 (F103) is connected with the reaction vessel (D101); the storage tank 4 (F104) is connected with the reaction vessel (D101); the condenser (C101) is connected with the reaction vessel (D101); and the barrel wall thickness of the storage tank 1 (F101) is 6 to 7 mm.

Carbohydrate detectors employing abiotic fuel cell designs are disclosed. The detectors produce current output using reactions between chemical dyes in alkaline solutions and carbohydrates, such as glucose. A linear relationship between current output of the detector and glucose concentration has been observed. This relationship may be used with measurements of current output when the glucose concentration is unknown to determine the unknown glucose concentration. In certain embodiments, the abiotic detectors may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts (i.e., precious metals or biocatalytic species) for glucose detection Organic dyes, such as methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators.

The present invention relates to an improved process for preparation of Indigo carmine of Formula (I), in high purity, more than 99.5%.

The present invention relates to an improved process for preparation of Indigo carmine of Formula (I), in high purity, more than 99.5%.