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49 results about "Drug prevention" patented technology

Novel seabed base

The invention provides a novel seabed base. The novel seabed base comprises a baseboard with the circumference uniformly provided with a group of supporting plates, the baseboard is connected with a main releaser, the main releaser is connected with a main floating body, the main floating body is provided with the main releaser, the main releaser is in communication connection of a communication station arranged outside the seabed base, the supporting plates is connected with a main floating body release rope bin, main floating body release ropes respectively connected with the supporting plates and the main floating body are arranged in the main floating body release rope bin, and the main floating body is also connected with a marine apparatus and a tracker; and a drug prevention cover is connected between every two adjacent supporting plates in a matching manner, and drug prevention covers match with the baseboard to form a closed conical structure with a cavity. The novel seabed base is convenient to transport and carry, a serially connected single releaser control single floating body double-insurance system is adopted, floating body effluent GPS tracing positioning is carried out to constantly monitor the position of an apparatus, and baffle plates are arranged below the bottom rack of the seabed base to prevent the bottom net drug in order to prevent fish-up of the seabed base.
Owner:云升军

Golden pomfret cultivating method

The invention relates to the field of aquaculture, particularly to a golden pomfret cultivating method. The method comprises the steps of controlling cultivating conditions, additionally installing meshes, screening, changing netting and the like in a fry putting process and the daily management process, enabling the golden pomfret fry to quickly adapt to the growing environment in the sea area, thereby the fry can be directly put in the deep sea area for realizing deep sea cage, the growth process of the golden pomfret from fry to finished fish is completed in the same environment, the cost of repeated transport is reduced, the stress response of the golden pomfret caused by the change of environment is also reduced, the morbidity and mortality are greatly lowered, drug prevention is not needed in the whole farming process, the growth environment of the golden pomfret is near to the wild condition, and the quality of the commodity is greatly improved.
Owner:LINGAO HAIFENG BREEDING DEV

Live coccidiosis vaccine and application thereof

The invention relates to the technical field of prevention and control of livestock and poultry diseases, in particular to a live coccidiosis vaccine and application thereof. The vaccine comprises a coccidiosis virulent strain and a coccidiosis attenuating strain having the same parasitic site or having the same parasitic site at any one or more stages of the parasitic life history; in the vaccine, the oocysts number ratio of the coccidiosis attenuated strain to the coccidiosis virulent strain is 50:1-3:1. A high dose of the weakly pathogenic coccidiosis strain is used for producing a competitive occupying advantage for a highly pathogenic strain having the same parasitic site, a occupying effect of the symbiotic pathogen in vaccine components is established, and the fertility, pathogenicity and damage to a host caused by over-intake are reduced after the highly pathogenic strain is immunized as the vaccine components. The coccidiosis vaccine can effectively improve the safety of the vaccine, reduce the cost of drug prevention and control, and have a good application potential while ensuring the immune efficacy of the vaccine.
Owner:CHINA AGRI UNIV

Prevention method for strawberry anthracnose

The invention relates to a prevention method for strawberry anthracnose. According to the prevention method for the strawberry anthracnose, drug prevention and physical cure are conducted simultaneously at the seedling stage. The drug prevention is: drug is sprayed every 13-15 days from the first day of the seedling planting to two months, every 7-8 days from the second month to the fourth month and till the planting or transplant rejuvenation period; and after the planting or transplant rejuvenation period, the drug is sprayed every 13-15 days till the bud appearing period, then the drug prevention is stopped. The physical cure is: pruning old and sick leaves at the position of 1-2cm away from the strawberry root; pruning the creeping stem from the root; and drug treatment is conducted before the planting of the strawberry. After three years of experience and practices and the popularization and application in Dandong areas, the prevention method for the strawberry anthracnose can greatly improve the survival rate after the planting of strawberries, creates considerable economic benefits for strawberry growers, and promotes the development of the local strawberry industry to a certain extent.
Owner:DONGGANG YIQUAN TOWN AGRI TECH EXTENSION STATION

Use of motherwort in the preparation of medicines for preventing and treating ischemic stroke

InactiveCN102258511AOrganic active ingredientsCardiovascular disorderSuperoxideCentral sulcus artery
The invention belongs to the field of traditional Chinese medicine pharmacy, and relates to the application of the specific monomer leonurine in the Chinese herbal medicine motherwort in the preparation of pharmaceutical compositions, especially the application in the preparation of medicines for preventing and treating ischemic stroke. The present invention studies the middle cerebral artery occlusion experimental model through craniotomy, and the results show that the motherurine can improve the activity of glutathione peroxidase and superoxide dismutase; reduce lipid peroxidation products The level of malondialdehyde can reduce the size of cerebral infarction; increase the expression of Bcl-2 and reduce the expression of Bax protein; reduce the degree of mitochondrial swelling and increase the level of membrane potential. The result proves that said motherwortine has obvious protective effect on ischemic brain tissue, and can be used to prepare medicines for preventing and treating ischemic apoplexy.
Owner:FUDAN UNIV

Social anti-poison and anti-epidemic method and multifunctional invisible protective mask

InactiveCN111296929ANo pollution in the processStrong social epidemic prevention applicabilityHuman health protectionDispersed particle filtrationFiltrationOxygen ions
The invention belongs to the field of social anti-poison and anti-epidemic methods and protective masks. Air with viruses, bacteria, poison gas and dust is sequentially filtered and disinfected by a filtering and disinfecting module of the breathing gas filtering and disinfecting cleaner, adsorbed and filtered by an adsorption and filtering module, assisted by a drug prevention and treatment module to moisten the lung and detoxify, added with negative oxygen ions by a negative oxygen ion module and filtered by an ultrafine filtering module at the bottom; therefore, high-cleanness beneficial air is conveyed to the invisible mask on the face, and it is guaranteed that inhaled air is clean and safe; the exhaled air is disinfected and filtered, so that infection of virus carriers to surrounding people is prevented. The invisible mask is small, exquisite, attractive and comfortable, and the wearing protection problem of people in daily work and life can be well solved; by adopting multipletechnologies such as functional modularization, chromatography filtration and desorption, the mask is wide in application, long in service life and low in average daily cost, and is mainly used for social poison prevention, epidemic prevention, flu prevention, haze prevention, industrial and mining dust prevention, household fire protection, formaldehyde removal and the like.
Owner:CHINA INNOVATION STATE WEALTHY (BIJING) SCI & TECH DEV RES INST CO LTD

A kind of medicine for preventing and treating bacterial wilt and its production and application method

A medicine for preventing and treating bacterial wilt, which is prepared from the following raw materials: silver agent, auxiliary agent, solid synergist, liquid synergist, deionized water and solid additive. One of the production methods is to disperse silver agent in ethanol, add stabilizer, antioxidant, anti-ultraviolet agent in sequence, and then add liquid synergist and dispersant; mix solid synergist and anti-caking agent, dry Drying and crushing; crushing solid additives; stirring and mixing the components obtained in the first step and the third step; stirring and mixing the components obtained in the second and fourth steps; vacuum packaging. The second is to dissolve the dispersant in deionized water and stir evenly; disperse the silver agent in ethanol, add stabilizer, antioxidant, anti-ultraviolet agent, and dispersant in sequence; add liquid synergist to the obtained components , add deionized water to a sufficient amount, stir well; pack the medicinal material. For root irrigation or soil mixing or root spraying. The pesticide of the invention has an effective rate of 80% to 100% against bacterial wilt, helps crops resist diseases and promotes agricultural development.
Owner:胡克矩

Novel method for controlling and preventing pumpkin southern blight

InactiveCN108370890APrevention and treatment of canker soresIncrease productionPlant protectionFruit crop cultivationDiseased plantOrganic fertilizer
Provided is a novel method for controlling and preventing the pumpkin southern blight. The method is characterized by comprising the steps of rotation, combined land preparation, adjustment of soil pH, deep application of fully decomposed organic fertilizers, frequent inspection and early detection of diseased plants, ploughing under great depth, drug prevention and control and the like, the purpose of preventing and controlling the pumpkin southern blight is achieved, and the method not only is easy to operate, but also can effectively improve the yield and quality of pumpkins, and is suitable for the prevention and control of the pumpkin southern blight.
Owner:张瑞芹

Efficient detection device for drugs

The invention relates to the field of drug prevention, in particular to an efficient detection device for drugs. The device comprises a box body, wherein the left side wall and the right side wall inthe box body are independently welded with a first rack; the inner side of each first rack is meshed with a first gear; the first gears are connected with a connecting plate through spindles; the leftend of the lower side of the connecting plate is provided with a first motor; the inner side of the connecting plate is provided with a first spacing groove; the middle of the connecting plate is provided with a rotation disk; the left end and the right end of the upper side of the rotation disk are connected with a connecting cover through supporting blocks; the rear side of the connecting coveris connected with a third motor through a fixed part; the front side of the third motor is connected with a third connecting shaft through a coupling; the outer side of the third connecting shaft isprovided with a second gear; the upper side and the lower side of the second gear is provided with a rack; the outer side of each rack is welded with an L-shaped connecting plate; and the outer sidesof the L-shaped connecting plates of the left end and the right end are independently provided with a detector and an infrared probe. By use of the device, the equipment can effectively and conveniently carry out rotatable detection on the drugs, in addition, the equipment can be effectively protected, and the equipment can prevent from being damaged.
Owner:NANJING FOREST POLICE COLLEGE

Traditional Chinese medicine preparation special for local anesthesia and preparation method thereof

The invention discloses a traditional Chinese medicine preparation special for local anesthesia. The traditional Chinese medicine preparation is prepared from the following main raw materials by weight: 3-5 parts of Datura metel, 1-3 parts of Radix Aconiti Kusnezoffii, 1-5 parts of dragon's bone, 2-4 parts of licorice, 5-10 parts of mint, 6-18 parts of Chinese prickly ash, 5-15 parts of myrrh, 10-20 parts of as arum, 6-12 parts of saffron, 3-8 parts of radix angelicae pubescentis, 1-3 parts of scorpion, 1-3 parts of centipede, 2-5 parts of fructus liquidambaris, 3-7 parts of safflower, 5-9 parts of rhodiola root, 5-10 parts of tribulus terrestris, 3-7 parts of Chinese honeylocust spine, and 2-6 parts of Arenaria taibaishanensis, etc. The traditional Chinese medicine preparation special for local anesthesia provided by the invention "pays attention to the whole", can be used for local anesthesia, and also can be used for local pain after local anesthesia, thus being a major characteristic different from drug prevention. Also, the traditional Chinese medicine preparation special for local anesthesia is prepared completely according to the principles of traditional Chinese medicine, is safer and more reliable, and has no toxic or side effect.
Owner:钱培培

Application of the substance reducing the combination of β-arrestin 1 and aph-1 protein in the preparation of drugs for preventing and treating neurodegenerative diseases

The invention relates to the application of a substance reducing the combination of β-arrestin 1 and APH-1 protein in the preparation of drugs for preventing and treating neurodegenerative diseases. The present invention reveals for the first time that β-Arrestin1 can interact with APH-1, an essential component of γ-secretase, thereby affecting the activity of γ-secretase. The present invention also discloses an isolated protein fragment of APH‑1AL and APH‑1B, the protein fragment is not only the target of the interaction between β-arrestin 1 and γ-secretase-related components, but also can be used to interfere with β ‑Arrestin 1 interacts with APH‑1, thereby inhibiting amyloid production and associated neurodegenerative diseases. The invention also discloses a method for screening drugs for preventing and treating neurodegenerative diseases.
Owner:CENT FOR EXCELLENCE IN MOLECULAR CELL SCI CHINESE ACAD OF SCI

Fruit tomato cultivation method

A fruit tomato cultivation method includes following steps: land preparation and fertilization, ridging, drug prevention, planting, artificial pest prevention and control in the initial flowering period. Cherry tomato which is a green fruit-vegetable is short in production period, the method is quick in action, and fruit shape is uniform and beautiful. An adopted planting method is an ecological and environment-friendly planting mode, a production chain is provided, people around can be driven to provide technical service and help, and job opportunities can be provided for township people. Taking planting of 220000 plants of cherry tomato as an example, sales value is expected to reach ten million, employment of more than 200 people around villages and towns can be solved, and technical service and help can be provided to the people around by more than 100 times.
Owner:沈阳保丰亿德农业科技有限公司

Prevention and treatment method for Chinese angelica coarse barkdiseases

The invention discloses a prevention and treatment method for Chinese angelica coarse barkdiseases. The problems that due to the fact that in the prior art, when only agricultural prevention and treatment are adopted, the effect is not good, when only chemical prevention and treatment are adopted, pesticide residues exist, and the quality of Chinese angelica is damaged are solved. By adopting the combination of agricultural control and chemical control, the method comprises the following steps of plot selection and prevention and treatment in processing, prevention and treatment in seedling growing process, prevention and treatment in the transplanting stage, root-irrigation prevention and treatment in the medicine formation period. According to the method, by adopting the combination of agricultural prevention and treatment and chemical drug prevention and treatment, prevention and treatment of Chinese angelica coarse barkdiseases can be performed, the effect is exact, pesticide residues are not caused, and the quality of the Chinese angelica is not affected.
Owner:成都众宜坊农业开发有限公司

Heat dissipation index of livestock and poultry bodies and prevention scheme of livestock and poultry climate stress risk

The invention discloses a heat dissipation index of livestock and poultry bodies and a prevention scheme of livestock and poultry climate stress risk. The disclosed index CTI=C0-(0.026+0.564 W+0.0181delta t*W)*delta t*V. According to the physical characteristics of the influence of three main physical factors of temperature, humidity and wind power on the heat dissipation, the heat dissipation index and algorithm of the livestock and poultry bodies for evaluating the influence of the environment on the heat dissipation of the bodies are constructed. According to the invention, based on the magnitude of the heat dissipation index CTI of the livestock and poultry, the environmental climate is classified into three types of cold stress, suitable stress and heat stress, and in each type, thegrading design is carried out according to the climate heat dissipation index based on to the potential risk of causing the stress, according to the classification system, the corresponding measures are established, in the aspects of physiology, nutrition, environmental sanitation reform, drug prevention, and the like, the health of livestock and poultry and the quality of livestock and poultry products are ensured.
Owner:NORTHWEST A & F UNIV

Physiotherapy water with tendon relaxing and blood circulation activating efficacy and preparation method thereof

The invention discloses a physiotherapy water with tendon relaxing and blood circulation activating efficacy. The physiotherapy water is prepared from the following main raw materials by weight: 3-5 parts of astragalus, 1-3 parts of Angelica sinensis rootlet, 1-5 parts of pangolin, 2-4 parts of musk, 5-10 parts of cyperus rotundus, 6-18 parts of frankincense, 5-15 parts of myrrh, 10-20 parts of peach kernel, 6-12 parts of saffron, 3-8 parts of radix angelicae pubescentis, 1-3 parts of scorpion, 1-3 parts of centipede, 2-5 parts of fructus liquidambaris, 3-7 parts of rhizome of Arisaema heterophyllum Blume, 5-9 parts of raw pinellia ternate, 5-10 parts of tribulus terrestris, 3-7 parts of Chinese honeylocust spine, and 2-6 parts of sappan wood, etc. The physiotherapy water with tendon relaxing and blood circulation activating efficacy provided by the invention "pays attention to the whole", and can treat diseases and also can strengthen body and prevent diseases, thus being a major characteristic different from drug prevention. The physiotherapy water with tendon relaxing and blood circulation activating efficacy provided by the invention is prepared completely according to the principles of traditional Chinese medicine, is safer and more reliable, and has no toxic or side effect.
Owner:马万里

CT scanning detecting device for drugs

The invention relates to the drug prevention field, and particularly to a CT scanning detecting device for drugs. The device comprises a chamber. The back end of top of the chamber is provided with aconnecting cover. The left sidewall and the right sidewall in the connecting cover are provided with racks. The inside part of the rack engages with a second gear. The second gear is connected with aconnecting board through a third rotating shaft. The upper side of the connecting board is provided with a connecting cover which is fixedly mounted. The right end of the connecting cover is providedwith a fourth motor. A third gear is mounted below the fourth motor. The left side of the third gear engages with a fourth gear. The fourth gear is internally provided with a connecting shaft. The lower side of the connecting shaft is provided with a rotating board. The left end and the right end at the lower side of the rotating board are provided with fixed rods which are welded. A supporting board is welded below the fixed rods. The middle part of the lower side of the supporting board is provided with a second ray source detector scanning device. The left portion and the right portion of the lower side of the supporting board are provided with a pair of fixed blocks which are welded. The CT scanning detecting device can effectively facilitate CT scanning surface detecting on the drugs,thereby effectively preventing transportation and carrying of the drugs.
Owner:NANJING FOREST POLICE COLLEGE

Method for inducing and domesticating wild Sinilabeo decorus tungting

InactiveCN101480170BAdjust feeding activity at any timeImprove water qualityClimate change adaptationPisciculture and aquariaDiseaseSinilabeo decorus tungting
The invention discloses a method for inducing and domesticating wild Sinilabeo decorus tungtings, which comprises the following steps of selecting a site for building a pit, collecting wild Sinilabeo decorus tungtings, mixing and culturing the wild Sinilabeo decorus tungtings, casting feed and inducing and domesticating the wild Sinilabeo decorus tungtings. The invention domesticates the wild Sinilabeo decorus tungtings under the discharge condition of the cement pit, enables the wild Sinilabeo decorus tungtings to reach a live rate higher than 95 percent and favorably grow and develop, provides technological conditions for saving, protecting and utilizing rare species, changes the food habit of the Sinilabeo decorus tungtings from the scrape of sessile algae into the intake of commercialfeed for benefiting the growth and the development. The pit has favorable water quality, freely intakes and distains water, is convenient to observe and can adjust the food intake of the Sinilabeo decorus tungtings at any time. In a fish disease sensitive period, fish diseases can be controlled by environment improvement and drug prevention so as to solve the problem that the wild Sinilabeo decorus tungtings are still not cultured in batches in the technical field of aquiculture and realize the mass industrialization development of the Sinilabeo decorus tungtings.
Owner:湖南省水产科学研究所

Drug prevention and control device for sheep brucellosis

The invention provides a drug prevention and control device for sheep brucellosis, and belongs to the field of animal husbandry quarantine. According to the technical scheme, the device comprises a drug prevention and control fence, a limiting mechanism arranged on the drug prevention and control fence and a translation mechanism, and further comprises an intermittent injection mechanism arrangedon the translation mechanism, wherein the drug prevention and control fence comprises a pair of side fences arranged in parallel; a plurality of auxiliary supporting rods are vertically arranged in the side fences; the limiting mechanism comprises a plurality of vertical plates arranged on the inner sides of the side fences; limiting air bags are arranged on the inner sides of the multiple vertical plates; soft layers are arranged on the outer surfaces of the limiting air bags; the translation mechanism comprises inverted-L-shaped sliding blocks arranged on the side fences on the two sides anda driving assembly A for driving the inverted-L-shaped sliding blocks; a transverse rod is arranged between the inverted-L-shaped sliding blocks on the two sides; and the intermittent injection mechanism is arranged on the transverse rod. The device has the beneficial effects that the operation is simple, multiple times of medicament injection can be completed, quarantine and prevention and treatment are simpler and more convenient, a large amount of manpower is saved, and the working efficiency is greatly improved.
Owner:山东省动物疫病预防与控制中心 +1

A drug ct scanning detection device

The invention relates to the field of drug prevention, in particular to a drug CT scanning detection device, which includes a cavity, a connection cover is provided at the top and rear end of the cavity, racks are provided on the left and right side walls inside the connection cover, and the inner sides of the racks are engaged with each other. There is a second gear, the second gear is connected to a connecting plate through the third rotating shaft, a connecting cover is fixedly installed on the upper side of the connecting plate, a fourth motor is installed on the right end of the connecting cover, a third gear is installed on the lower side of the fourth motor, and the third gear The fourth gear meshes on the left side, and a connecting shaft is installed inside the fourth gear. A rotating plate is fixedly installed on the lower side of the connecting shaft. Fixed rods are welded at the left and right ends of the lower side of the rotating plate, and a support plate is welded on the lower side of the fixed rod. The second ray source detector scanning device is installed in the middle part of the lower side, and the first ray source detector scanning device is installed on the left and right sides of the lower side of the support plate. The present invention can effectively facilitate the CT scanning detection of drugs by the equipment, which can effectively Put an end to the transportation and carrying of drugs.
Owner:NANJING FOREST POLICE COLLEGE

Debilitating agent for highly toxic chicken coccidian and its preparation

The invention relates to a poisonous chicken coccidia weakening agent and a preparation method, which is prepared from the following material components: potassium dichromate, sodium chloride, sodium bicarbonate, glucose, potassium chloride , sodium azide, distilled water. The attenuating agent of the present invention can be used to weaken various virulent strains of chicken coccidia such as tender, heap type, giant, poisonous and Eimeria precocci etc., and it is safe and reliable to inoculate chicks with the weak coccidia vaccine of the present invention, and Has good immunogenicity. The production facility of the present invention is simple, the cost is low, and the production investment of chicken coccidiosis vaccine can be reduced, the cycle is fast, the method is simple and practical, and it is convenient for popularization and application in rural areas. The cost is about 0.30 yuan / feather. After the control, the mortality rate of chickens is reduced, the egg production rate is increased, and the growth rate is accelerated.
Owner:顾有方

A termite detection device and detection method thereof

The invention discloses a termite detection device and a detection method thereof. The device comprises a shell with openings allowing termites to enter and bait bars arranged in the shell, each bait bar is provided with a sealed deep hole, and each deep hole is internally provided with an air pressure sensor; the device further comprises air bottles and a controller; the air bottles are communicated with the deep holes through a switch, and when the switch is switched on, the air bottles inflate the deep holes; the controller is connected with the air pressure sensors and used for judging whether air pressure sensed by the air pressure sensors reaches a preset air pressure value or not after a first preset time after the switch is switched on, if yes, it is shown that the deep holes are not bitten through by the termites, and if not, it is shown that the deep holes are bitten through by the termites. The method comprises the steps that the switch is switched on, and the deep holes are inflated; after the first preset time, whether the air pressure reaches the preset air pressure value or not is judged, and therefore whether the deep holes are bitten through or not is judged. According to the termite detection device and the detection method thereof, no drug prevention is needed, the environment cannot be polluted, the application range is wide, and the false alarm rate is low.
Owner:ZHEJIANG DEKAN ENVIRONMENT TECH CO LTD

Chess for cultivating people to actively receive drug control education

The invention discloses a chess for cultivating people to actively receive drug control education. The chess comprises a chessboard and chess paper, pressing strips which are mutually connected are arranged at the periphery of the chessboard, and are in contact with the upper surface of the chessboard, the chess paper is fixed above the chessboard through the pressing strips, grooves are formed inone ends of the pressing strips, protrusions are arranged at the other ends of the pressing strips, the grooves are matched with the protrusions, and the pressing strips are connected end to end in sequence; the chess paper comprises a paper chessboard body, dices, game chess pieces and a card box, the card box is loaded with a card A, a card B, a card C, a card D, a card E, a card F and a card G, the front of the card A represents policemen, the front of the card B represents drug control young volunteers, the front of the card C represents drug control social workers, the front of the D represents teachers, and the fronts of the card E, card F and card G represent breakthrough test cards with different color checks on the chessboard body. By means of the chess, the ability and interestof young people in learning drug prevention educational knowledge are improved.
Owner:YUNNAN POLICE COLLEGE

A device for the prevention and treatment of porcine eperythrozoonosis drugs in veterinary experiments

The invention discloses a drug prevention and treatment device for Eperythrozoonis porcine in veterinary experiments. The bottom of the blood-drawing needle is fixedly connected with a blood vessel, the bottom of the blood vessel is provided with an injection needle, and the inside of the injection needle is slidably connected with a liquid pushing block, and the opposite sides of the two elastic gear bars are provided with The liquid sealing plate, the opposite sides of the two liquid sealing plates are fixedly connected with the drug release block through the connecting rod, the blood collection box is provided at the bottom of the blood vessel, and the drug collection box is provided at the bottom of the injection needle, The bottom of the medicine collecting box is fixedly connected with a limit spring. In this veterinary experiment, the drug prevention and control equipment for Eperythrozoonosis porcine can track the diseased pigs through the combination of the fixed box and the clock, and can detect the body temperature regularly and judge whether the drug is injected.
Owner:JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE

Application of o-(tetrahydropyrrolyl)ethyl derivatives of cleistanone cleistanone in the preparation of drugs for preventing and treating liver damage

The invention relates to the fields of organic synthesis and medicinal chemistry, in particular to an O-(tetrahydropyrrolyl)ethyl derivative of cleistanone, a preparation method and its application in the preparation of drugs for preventing and treating liver damage. The present invention synthesizes a new O-(tetrahydropyrrolyl) ethyl derivative of Cleistanone, and discloses its preparation method. Pharmacological experiments show that the O-(tetrahydropyrrolyl)ethyl derivative of Cleistanone of the present invention has the effect of preventing and treating liver damage, and has the value of developing drugs for preventing and curing liver damage.
Owner:NANJING UNIV

Use of Apigenin in preparation of drugs for inhibiting liver fibroblast proliferation

InactiveCN107865841AGood anti-hepatic fibrosis activityOrganic active ingredientsDigestive systemApigeninFibroblast
The invention discloses the use of Apigenin in the preparation of medicines for treating liver fibrosis. Pharmacological tests have proved that Apigenin can significantly inhibit the occurrence and development of liver fibrosis, and can be used to prepare drugs against liver fibrosis and liver cirrhosis. Apigenin belongs to a new skeleton type, and it has strong inhibitory activity on liver fibroblast proliferation Prominent substantive features, while being used against proliferation of hepatic fibroblasts clearly represent a significant advance.
Owner:ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD

Application of hederagenin and glucoside thereof to preparation of medicine for treating osteoporosis

InactiveCN107865876AReduced biomechanical strengthImprove intrinsic propertiesOrganic active ingredientsSkeletal disorderGlycosideOsteoporotic bone
The invention discloses application of hederagenin and glucoside thereof to the preparation of a medicine for treating osteoporosis. The invention provides application of hederagenin with the sequencenumbers being 1 to 15 or glucoside to the preparation of the medicine for treating osteoporosis. The hederagenin with the sequence numbers being 1 to 15 or glucoside can obviously restrain the decrease of the bone mineral density of an ovariectomized rat, and can obviously improve the inherent properties of the thighbone of the ovariectomized rat. Results show that the hederagenin with the sequence numbers being 1 to 15 or glucoside can obviously improve bone properties of the model rat with osteoporosis, and can be developed into the medicine for preventing and treating osteoporosis.
Owner:CHINA PHARM UNIV

Human anti-h7n9 avian influenza virus neutralizing antibody h8, its preparation method and application

The present invention provides a human anti-H7N9 avian influenza virus neutralizing antibody H8 screened by phage surface display technology, the amino acid sequences of its light chain and heavy chain variable regions are respectively as SEQ ID No.1 and SEQ ID No. 2 shown. The antibody can specifically recognize the H7N9 virus particle antigen, can have a significant enzyme-linked immune reaction with the H7N9 virus, and has a neutralizing activity against H7N9 virus infection. In addition, the antibody of the present invention can be made into a specific antibody drug for preventing and treating H7N9 avian influenza virus, so as to be clinically used for preventing and treating acute respiratory infectious diseases caused by H7N9 virus.
Owner:INST OF PATHOGEN BIOLOGY CHINESE ACADEMY OF MEDICAL SCI
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