93 results about "Cleistanone" patented technology

The invention relates to the field of organic synthesis and medicinal chemistry, and in particular relates to an O-(piperidyl)ethyl derivative of Cleistanone, a preparation method thereof and application in preparation of anti-low erythrocyte anemia drugs. The invention synthesizes a new O-(piperidyl)ethyl derivative of Cleistanone and discloses its preparation method. Pharmacological experiments show that the O-(piperidyl)ethyl derivative of Cleistanone provided by the invention has an anti-low erythrocyte anemia effect, and has the value of developing anti-low erythrocyte anemia drugs.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and an application thereof in the preparation of antibacterial drugs. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Shown by pharmacological experiments, the Cleistanone derivative disclosed by the invention has an antibacterial effect and has a value in the development of the antibacterial drugs.

The invention relates to the field of organic synthesis and medicinal chemistry, particularly to an O-(piperidinyl) ethyl derivative of Cleistanone as well as a preparation method for the O-(piperidinyl) ethyl derivative of the Cleistanone and the application of the O-(piperidinyl) ethyl derivative of the Cleistanone in preparing drugs for resisting heart failure. The invention synthesizes a novel O-(piperidinyl) ethyl derivative of the Cleistanone and discloses the preparation method thereof. Pharmacological experiment results show that the O-(piperidinyl) ethyl derivative of the Cleistanone has the function of resisting heart failure and has the value of developing drugs for resisting heart failure.

The invention relates to the field of organic synthesis and medicinal chemistry and particularly to an O-(piperidinyl) ethyl derivative of Cleistanone, a preparation method for the O-(piperidinyl) ethyl derivative of the Cleistanone and the application of the O-(piperidinyl) ethyl derivative of the Cleistanone in preparing drugs for resisting chronic obstructive pulmonary diseases. The invention synthesizes a novel O-(piperidinyl) ethyl derivative of the Cleistanone and discloses the preparation method thereof. Pharmacological experiment results show that the O-(piperidinyl) ethyl derivative of the Cleistanone has the function of resisting chronic obstructive pulmonary diseases and has the value of developing drugs for resisting chronic obstructive pulmonary diseases.

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to an O-(piperazinyl) ethyl derivative of cleistanone, a preparation method of the O-(piperazinyl) ethyl derivative of cleistanone and use of the O-(piperazinyl) ethyl derivative in preparing an antibacterial drug. In the invention, the novel cleistanone derivative is synthesized and the preparation method of the novel cleistanone derivative is disclosed. A pharmacology experiment shows that the cleistanone derivative has an antibacterial effect and a value for developing the antibacterial drug.

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to a cleistanone derivative, and a preparation method and an application thereof in preparation of antibacterial drugs. The new cleistanone derivative is synthesized, and the preparation method is disclosed. Pharmacological experiments indicate that the cleistanone derivative has an antibacterial effect and has a value of development of the antibacterial drugs.

The invention relates to the fields of organic synthesis and pharmaceutical chemistry, in particular to O-(piperazinyl) ethyl derivative of cleistanone, and a preparation method and the application of the O-(piperazinyl) ethyl derivative to the preparation of medicine for resisting acute gout. The invention compounds new O-(piperazinyl) ethyl derivative, and discloses a preparation method thereof. Pharmacology experiments show that the O-(piperazinyl) ethyl derivative has the effect of resisting acute gout, and has the value of developing medicine for resisting acute gout.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and use thereof in the preparation of anti-rhinitis drugs. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Shown by pharmacological experiments, the Cleistanone derivative disclosed by the invention has an anti-rhinitis effect and has a value in the development of the anti-rhinitis drugs.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of heart failure resisting drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has a heart failure resisting effect and has a value in the development of the heart failure resisting drugs.

The invention relates to the fields of organic synthesis and pharmaceutical chemistry, in particular to a Cleistanone O-(imidazolyl) ethyl derivative, and a preparation method and application thereof in the preparation of anti-rhinitis drugs. The invention synthesizes a new Cleistanone O-(imidazolyl) ethyl derivative and discloses a preparation method thereof. Pharmacological experiments prove that the Cleistanone O-(imidazolyl) ethyl derivative has the effect of resisting to rhinitis and has the value of anti-rhinitis drug development.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of anti-hypoxia drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has an anti-hypoxia effect and has a value in the development of the anti-hypoxia drugs.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(piperazinyl)ethyl derivative, a preparation method thereof and use thereof in the preparation of hepatic fibrosis resisting drugs. According to the invention, a novel Cleistanone O-(piperazinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(piperazinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(piperazinyl)ethyl derivative disclosed by the invention has a hepatic fibrosis resisting effect and has a value in the development of the hepatic fibrosis resisting drugs.

The invention relates to the fields of organic synthesis and pharmaceutical chemistry and particularly relates to O-(pyrrolidin)ethyl derivatives of Cleistanone, a preparation method of the O-(pyrrolidin)ethyl derivatives of Cleistanone and an application of the O-(pyrrolidin)ethyl derivatives of Cleistanone to preparation of an anti-osteoporosis drug. The invention discloses novel O-(pyrrolidin)ethyl derivatives of Cleistanone and a preparation method of the novel O-(pyrrolidin)ethyl derivatives of Cleistanone. Pharmacological experiments prove that the O-(pyrrolidin)ethyl derivatives of Cleistanone have an anti-osteoporosis effect and has a value of developing the anti-osteoporosis drug.

The invention relates to the fields of organic synthesis and pharmaceutical chemistry, and specifically relates to a cleistanone O-(benzimidazolyl) ethyl derivative, a preparation method thereof, and an application of the cleistanone O-(benzimidazolyl) ethyl derivative in the preparation of anti-inflammatory drugs. A novel cleistanone O-(benzimidazolyl) ethyl derivative is synthesized, and a preparation method thereof is disclosed. The pharmacological experiments show that the cleistanone O-(benzimidazolyl) ethyl derivative has an anti-inflammatory effect and can be used to develop anti-inflammatory drugs.

The invention relates to the fields of organic synthesis and pharmaceutical chemistry and specifically relates to an O-(1H-tetrazolyl) ethyl derivative of cleistanone, a preparation method and application thereof in preparation of medicines for treating or preventing renal fibrosis. The invention synthesizes a new O-(1H-tetrazolyl) ethyl derivative of cleistanone and discloses the preparation method thereof. Pharmacological experiments show that the O-(1H-tetrazolyl) ethyl derivative of cleistanone has an effect for preventing or treating the renal fibrosis and has the value of developing the medicines for preventing or treating the renal fibrosis.