71 results about "Alcohol Toxicity" patented technology

The invention relates to a health-care product composite with an alcoholism relieving function and a preparation method thereof, and discloses a health-care product composite with an alcoholism relieving function and a preparation method thereof. The composite is prepared from the following raw materials: pueraria flower, hovenia dulcis thumb, kudzuvine root, green tea and oligosaccharide, wherein plantain herb, chrysanthemum, lalang grass rhizome, liquoric root, tangerine peel and hawthorn fruit are also added into the raw materials of the composite. The health-care product composite is prepared by refining wild plants, does not have toxic or side effect, has excellent effects of relieving alcoholism and activating spleen and protecting liver and stomach, and can eliminate or relieve acute mild and moderate alcoholism, acute stomach injury, chronic gastritis and acute liver injury which are caused by drinking. The health-care product composite can be prepared into granules, tea bags and capsules.

The invention relates to a traditional Chinese medicine preparation having functions of neutralizing the effect of alcoholic drink, reducing blood fat and protecting the liver and cardio-cerebral blood vessels, which comprises the following compositions: 20 to 80 percent of pollen pini, 10 to 70 percent of kudzu root extract, 5 to 50 percent of nutmeg extract and 5 to 30 percent of auxiliary materials. The traditional Chinese medicine preparation is health-care food prepared from pure natural food, namely the pollen pini, kudzu roots and nutmeg which are taken as main raw materials by a reasonable formula, specially aims to people suffering from chronic alcohol drinking, fat people and patients suffering from hypertension, hyperlipemia and hyperglycemia and chronic diseases, and achieves the aim of protecting chemical liver damage by protecting the liver and resisting lipid overoxidation damage of the liver caused by alcoholism. The pollen pini contains rich antioxidative substances, and can lighten lipid overoxidation damage of alcohol on the liver, strengthen metabolism of fatty acid in hepatocyte, and reduce fat deposition in the hepatocyte; the nutmeg has the function of regulating spleen and stomach; and the kudzu roots also have the function of relieving cerebral vasospasm, so that the traditional Chinese medicine preparation achieves the aim of relieving symptoms such as headache, stomach upset, dyspepsia and poor health after drinking.

The gene responsible for encoding SERT has a functional polymorphism at the 5′-regulatory promoter region, which results in two forms, long (L) and short (S). The LL-genotype is hypothesized to play a key role in the early onset of alcohol use. The present invention discloses the differences in treatment and diagnosis based on the L or short genotypes as well as on a single nucleotide polymorphism of the SERT gene, the 3′ UTR SNP rs 1042173. The present invention demonstrates the efficacy of using the drug ondansetron and similar drugs for treatment based on variations in the polymorphisms of the SERT gene as well as methods for diagnosing susceptibility to abuse of alcohol and other addiction-related diseases and disorders.

The present invention is directed to a screening mechanism for identifying members of the general population at increased risk for alcoholism and premenstrual syndrome. The screening mechanisms may be used to measure the expression of the α4β2δ GABAA receptors, in order to identify members of the general population as having an increased sensitivity to lower concentrations alcohol coupled with a decrease sensitivity to higher concentrations of alcohol, a scenario frequently found in patients suffering from alcoholism and premenstrual anxiety. Methods of screening for drugs which decrease expression of the α4β2δ subunit of GABAA are also provided.

A dark plum health wine comprises the used main raw materials by weight: 500 g of preserved fruits of dark plum, 30 g of medlar, 600 g of rice vinegar, 500 g of honey and 10000 g of a Baijiu base wine. A production process comprises the steps: taking 500 g of the preserved fruits of dark plum, 30 g of the medlar, 600 g of the rice vinegar and 500 g of the honey, placing into a jar, adding 10000 g of the Baijiu base wine, soaking, stirring for 3 times each day, after soaking for 6 days, filtering out all the raw materials in the wine, covering with a wine jar lid, putting under the sun, basking for 15 days, carefully filtering, and thus obtaining the product. The dark plum health wine not only has a flower and fruit sweet, tender and smooth mouthfeel, but also has strong and mellow strength of Baijiu, more has beautiful and bright color and luster, is comfortable when in mouth, is lingering in taste, and has strong alcohol capacity; and because alcohol toxicity is eliminated completely by the dark plum, the dark plum health wine does not burn hearts, make people feel dizzy, make mouth dry and make eyes acerbity with adequate drinking.

The invention discloses a composite (E) for disintoxicating and sobering, which is prepared by glucose and fructose, fruit glucose, honey, flower of kudzuvine, hoveniae semoveniae semen, L-alanine, L-ornithine, L-glutamine, L-carnitine according to a certain weight range. In order to enable the effect better, one or more of tea leaf, vitamin C, L-cysteine, taurine, L-asparaginic acid or L-aspartate, vitamin B1, vitamin B6, L-arginine, L-glutamic acid, L-proline, phaseomannite, vitamin B2, nicotinic acid, folic acid, vitamin B12 and pantothenic acid are also added. The composite can be prepared into liquid preparation, electuary and medicinal tea. The composite of the invention can be prepared into food and health food. The invention can quickly disintoxicate, sober, eliminate alcoholism symptom and continued effect of alcohol on a human body, and has no side effect.

The present invention relates to production of alcoholic beverage enriched with <1>H2 <16>O comparing with the typical alcoholic beverage. The alcoholic beverage enriched with <1>H2<16>O are provided by adding highly pure light water into the alcoholic beverage, wherein the weight of <1>H2<16>O are more than about 99.76% to about 99.99% in the highly pure light water. To add the highly pure light water into the alcoholic beverage composition, can lead to decrease the alcohol toxicity.

The invention provides a medicine for treating fatty liver, hepatitis and liver cirrhosis. The medicine is a mixture of glycoprotein or polysaccharide and protein, or is polypeptide or protein. After the medicine is adopted for treatment for 3 months, the content of ALT is reduced to 41.5-45.9 IU / L, the content of TbiL is reduced to 37.3-42.6 mu mol / L, the content of Alb is reduced to 32.6-35.0 g / L, the content of HBV-DNA is reduced to 4.0-4.9 copies / mL, the sputum negative conversion rate of HbeAg is 75-82%, and the sputum negative conversion rate of HBV-DNA is 83-87%. The medicine is suitable for treating fatty liver, alcoholic liver, alcoholism, hepatic fibrosis, viral hepatitis, hepatalgia, abdominal distension, cancer and cirrhosis, has the characteristics of being safe and efficient, and being free of side effects, and has the functions of absorbing and metabolizing alcohol in the body, and eliminating alcoholism.

The invention discloses a sobering-up acetic acid milky tea and a preparation method thereof. The sobering-up acetic acid milky tea comprises the following raw materials in parts by weight: 400-500 parts of degreased milk, 70-80 parts of watermelon, 40-50 parts of sugar cane, 20-30 parts of sweet oranges, 30-40 parts of tender bamboo leaves, 10-20 parts of dogbane leaves, 10-20 parts of apple blossoms, 6-7 parts of penthorum Chinense pursh, 3-4 parts of water chestnut leaves, 7-8 parts of prepared rehmannia roots, 1-2 parts of cade, 1-2 parts of roots of hollyhock, 4-5 parts of grifola, 20-30 parts of apple vinegar, 30-40 parts of a wheat gern powder and a proper amount of aroma enhancement carbon; according to the sobering-up acetic acid milky tea provided by the invention, the raw materials such as the tender bamboo leaves and the like are extracted by using the degreased milk after being baked by using the aroma enhancement carbon, so that the milky tea is full of charcoal roasted flavor, is full-bodied and unique, is added with raw materials having the efficacies of dispelling the effects of alcohol, protecting liver, alleviating alcohol toxicity, inducing diuresis and treating stranguria, thereby achieving a good hangover alleviating and alcohol dispelling effects, due to the addition of the apple vinegar, the sobering-up acetic acid milky tea is sour and sweet, tastes good, can adjust human body acid-base equilibrium and promote metabolization, the finished milky tea is brewed by using boiling water, is drunk before or after alcohol drinking, and can remarkably dispel the effects of alcohol, protect the liver, and refresh and restore consciousness.

The invention provides an alcohol disintoxicating and liver protecting tea, which is produced by processing raw materials with certain proportion of chrysanthemum, semen hoveniae, pueraria flower, radix puerariae, dried orange peel and Qing cha. The alcohol disintoxication and liver protection tea can clear away the heat and the toxic material, remove jump heat and can neutralize alcohol toxicitywith effective ingredients of the Chinese medicine, dissolve synthetically the alcohol toxicity in the stomach to the utmost extend, so that the alcohol toxicity can not enter the small intestine formetabolizing and getting drunk. Therefore, the tea can detoxicate the alcohol toxicity in time when the alcohol toxicity is not absorbed by the human body to achieve the aim of protecting the liver and the kidney.

The invention discloses a novel application of dihydromyricetin, namely an application of dihydromyricetin in preparation of food, health care products or medicines with a hangover alleviating effect.The dihydromyricetin has the advantages that the dihydromyricetin has a good hangover alleviating function, can be used for increasing the expression of hippocampus and neuronal GABAARs a4 subunits,has the effects of resisting alcoholism and alcohol dependence, can also effectively prevent liver reduced glutathione depletion and malondialdehyde increase caused by alcohol, reduces the content oftriglyceride, reduces the fatty degeneration degree of hepatocytes, and has good effects of preventing and treating alcoholic liver injury.

The invention discloses a composite (F) for disintoxicating and sobering, which is prepared by glucose and fructose, fruit glucose, honey, flower of kudzuvine, hoveniae semoveniae semen, L-alanine, L-ornithine, L-glutamine, L-carnitine according to a certain weight range. In order to enable the effect better, one or more of tea leaf, vitamin C, L-cysteine, taurine, L-asparaginic acid or L-aspartate, vitamin B1, vitamin B6, L-arginine, L-glutamic acid, L-proline, phaseomannite, vitamin B2, nicotinic acid, folic acid, vitamin B12 and pantothenic acid are also added. The composite can be prepared into liquid preparation, electuary and medicinal tea. The composite of the invention can be prepared into food and health food. The invention can quickly disintoxicate, sober, eliminate alcoholism symptom and continued effect of alcohol on a human body, and has no side effect.

The invention relates to the medical field, and discloses a liver-protecting composite. The raw materials comprise one of S-ademetionine, cysteine or methionine, vitamin C, flower of kudzuvine, hovenia dulcis thumb and rhizoma alismatis. The invention also provides a preparation method of the liver-protecting composite. The liver-protecting composite is taken after drinking, thus being capable of preventing chronic alcoholism and alcoholic cirrhosis; and the liver-protecting composite can be taken for a long term as a liver-protecting health care product, thus having wide application prospects.

Provided are compounds having the general structure according to Formula (I):Further provided are pharmaceutical compositions comprising these compounds. The invention still further provides methods of treating alcoholism, methods of reducing alcohol intake, methods of treating anhedonia, and methods of treating anxiety using theses compounds or the compositions containing them.

The invention relates to a hangover-alleviating liver-protecting health-preserving and health-care product formula which can improve the antioxidant capacity in organisms, effectively remove free radicals generated by alcohol metabolism, relieve excessive oxidation of lipid components on the surfaces of liver cell membranes and prevent acute toxicity of alcohol. 250 ml of liquid contains 280-320 mg of tea polyphenol, 1.8-2.2 g of moringa seeds, 1.8-2.2 g of flos puerariae, 2-3 g of semen hoveniae, 12-17 g of honey, 0.8-1.2 g of dried ginger, 1.8-2.2 g of ginseng, 2.8-3.2 g of poria cocos, 2.8-3.2 g of orange peel, 2.8-3.2 g of malt, 1.8-2.2 g of fructus amomi and 0.8-1.2 g of flos chrysanthemi. The hangover-alleviating liver-protecting health-preserving and health-care product formula hasthe advantages of effectively relieving drunkenness symptoms, preventing alcoholism and protecting the liver and stomach.

The invention relates to the microbial fermentation of gaseous substrates, particularly to methods of mitigating and / or reducing alcohol toxicity effects on a microbial culture at elevated alcohol concentrations during fermentation. The invention relates particularly to microbial fermentation of substrates comprising CO and the effects of alcohol toxicity are reduced or mitigated by maintaining the temperature below the optimum operating temperature by cooling the fermentation broth.