41 results about "Alcohol intake" patented technology

One or more alcohol inputs are received at the interactive system. Each of the alcohol inputs corresponds to an alcoholic beverage to be consumed by a consumer. The system calculates an estimated blood-alcohol level of the consumer based on the alcohol inputs. The estimated blood-alcohol level is compared with one or more alcohol impairment limits retrieved from an electronic data store. If the comparison reveals that the consumer might be impaired, an alert is automatically signaled.

This invention relates to novel compounds which are inhibitors of acyl coenzyme A: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination with weight management therapies or other triglyceride lowering therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, genetic (Type 1, Type 5 hyperlipidemia) and acquired forms of hypertriglyceridemia or hyperlipoproteinemia-related disorders, caused by but not limited to lipodystrophy, hypothyroidism, medications (beta blockers, thiazides, estrogen, glucocorticoids, transplant) and other factors (pregnancy, alcohol intake), hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, cardiovascular outcomes, angina, excess hair growth (including syndromes associated with hirsutism), nephrotic syndrome, fibrosis such as myocardial, renal and liver fibrosis, hepatitis C virus infection and acne or other skin disorders.

A composition for alleviation of alcohol induced hangover comprises Ssangwhatang including Hoveniae Semen or lactobacillus fermented Ssangwhatang as an effective ingredient. Specifically, the composition comprises Ssangwhatang including Hoveniae Semen extracts or lactobacillus fermented Ssangwhatang prepared by inoculating, culturing and fermenting or lactobacillus. The composition is useful in alleviation of alcohol induced hangover and reducing blood-alcohol concentration during alcohol intake when taken as a health food.

There is provided a composition useful for mitigating a physical burden and recovering from fatigue at the time of alcohol intake, within a safety dose of active ingredients. The composition is for accelerating alcohol metabolism and for relieving fatigue by gluconeogenesis in vivo, and is characterized by comprising an effective amount of caffeine and an effective amount of an amino acid(s) or a peptide(s) selected from the group consisting of serine, tryptophan, serine rich peptides, tryptophan rich peptides, serine / tryptophan rich peptides and mixtures thereof, as active ingredients.

The present invention relates to a method of reducing or preventing the symptoms associated with the intake of alcohol. The method comprises administering to a subject an effective amount of a pharmaceutical composition prior to alcohol intake. The pharmaceutical composition comprises a non-steroidal anti-inflammatory drug and a H1-antihistamine.

The invention discloses an oral solution with an auxiliary protection effect on chemical liver injuries. Each 100mL of the oral solution is mainly prepared from following raw materials: 4-16g of ginsengs, 30-60g of lobed kudzuvine roots, 20-70g of hovenia acerba lindl and a suitable amount of aromatic vinegar; the sourness of the oral solution is 2.5-3.5g / ml. The oral solution is a liver protection oral solution which integrally combines dual advantages of special flora of Hengshun aromatic vinegar and Chinese herbal medicinal ingredients including the ginsengs, the lobed kudzuvine roots, the hovenia acerba lindl and the like; with the adoption of the method, nutritional ingredients of all the raw materials are sufficiently released so as to accelerate digestion of a human body; the oral solution has the effects of relieving fatigues, accelerating the repairing of injured tissues, enhancing the liver detoxifying function, improving the immunity, and preventing drunkenness, hangover, alcoholism, alcoholic liver and the like, caused by excessive alcohol intake.

The invention relates to a composition for alcoholism prevention before and after drinking, in particular to a composition for protecting the liver, restoring consciousness and preventing hangover, and an anti-alcohol beverage using the composition. The composition comprises the following active ingredients: radix puerariae, ampelopsis grossedentata leaves, male flowers of eucommia, leucine, isoleucine, valine, vitamin C, vitamin B1 and vitamin B6. The composition can promote decomposition acceleration of alcohol in a body, and facilitates alcoholism prevention of an alcohol intake person. The composition protects a nervous system from alcohol attack and keeps the brain sober.

The invention relates to the technical field of fruit wine processing, in particular to blueberry enzyme fruit wine. The blueberry enzyme fruit wine can increase the utilization value of blueberries,and alleviates the problem of reduction in the added value due to excess of the blueberry planting industry; meanwhile, the blueberry enzyme fruit wine can guide healthy drinking and reduce damage ofexcessive alcohol intake to a human body. The blueberry enzyme fruit wine is prepared by mixing an enzyme stock solution and fruit wine according to a ratio of 3:7 and then curing, wherein the enzymestock solution is prepared by adding a variety of strains into a main material, an auxiliary material and pure water according to a weight ratio of 6:5:2 and then fermenting; the fruit wine is prepared by adding koji into the main material and fermenting; the main material comprises the blueberries and lemons; the auxiliary material comprises one or more of black sugar, brown sugar, tablet sugar,crystal sugar and molasses.

The invention provides an on-line alcohol intake amount monitoring system. The system comprises an air blowing device, an alcohol intake amount treating unit and a user mobile terminal, wherein the air blowing device is connected with the alcohol intake amount treating unit and can be taken along; the alcohol intake amount treating unit is connected with the user mobile terminal by wireless communication; the air blowing device is used for a user to breathe out air; the alcohol intake amount treating unit is used for analyzing and treating the expired air, feeding back the analysis data to the user mobile terminal and displaying the data on the user mobile terminal; the user mobile terminal can be connected with a designated driver mobile terminal by a communication network. The on-line alcohol intake amount monitoring system provided by the invention can be used for enabling the user to know the alcohol intake amount at any time so as to prevent drunk driving of the user; meanwhile, the user mobile terminal is connected with the designated driver mobile terminal, so the on-line alcohol intake amount monitoring system is convenient, rapid and capable of guaranteeing the safety of driving of the user and improving the concept of safe driving of people.

This invention relates to novel compounds which are inhibitors of acyl coenzyme A: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination with weight management therapies or other triglyceride lowering therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, genetic (Type 1, Type 5 hyperlipidemia) and acquired forms of hypertriglyceridemia or hyperlipoproteinemia-related disorders, caused by but not limited to lipodystrophy, hypothyroidism, medications (beta blockers, thiazides, estrogen, glucocorticoids, transplant) and other factors (pregnancy, alcohol intake), hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, cardiovascular outcomes, angina, excess hair growth (including syndromes associated with hirsutism), nephrotic syndrome, fibrosis such as mycocardial, renal and liver fibrosis, hepatitis C virus infection and acne or other skin disorders.

Provided are compounds having the general structure according to Formula (I):Further provided are pharmaceutical compositions comprising these compounds. The invention still further provides methods of treating alcoholism, methods of reducing alcohol intake, methods of treating anhedonia, and methods of treating anxiety using theses compounds or the compositions containing them.

A brain health food / brain health beverage for preventing / alleviating brain atrophy due to alcohol intake is developed. The brain health food or brain health beverage containing, as active ingredients,folic acid, vitamin B6, and vitamin B12, for preventing a decrease in the brain capacity of regular drinkers who are not suffering from dementia, i.e., healthy people, is characterized by containing,as active ingredients, 0.4-0.8 mg of folic acid, 10-20 mg of vitamin B6, and 0.25-0.5 mg of vitamin B12.

A composition includes a black chokeberry extract and at least one of a thistle extract, a black hoof mushroom extract and a mixture thereof. The composition is effective in preventing and treating non-alcoholic fatty liver disease caused by accumulation of fat in the liver due to excessive intake of nutrients or metabolic syndrome regardless of alcohol intake. The composition can improve the increase in liver weight, accumulation of neutral fat in the liver, increase in serum ALT concentration, and reduction of liver SOD activity and total antioxidant activity of the liver, in experimental animals grown with a high-fat diet. Since the fatty liver disease caused by a high-fat diet in experimental animals shows similar pathological and immunological manifestations to human non-alcoholic fatty liver disease, the composition can be provided as a pharmaceutical agent or health supplement food used to prevent and treat non-alcoholic fatty liver disease.

Proposed is an intestinal microbiome-improving composition containing ellagic acid as an active ingredient. The ellagic acid inhibits the growth of harmful bacteria such as Verrucomicrobia and Bacteroidetes attributable to alcohol intake and increases the growth of beneficial bacteria such as Firmicutes, thereby controlling intestinal microbes. As a result, the ellagic acid exhibits the effect of inhibiting an increase in a plasma endotoxin level, an increase in an intestinal TNF-α level, an increase in intestinal oxidative stress, a decrease in expression of intestinal TJ and AJ proteins, liver fat accumulation, an increase in plasma ALT, an increase in triglycerides, and hepatic oxidative stress and apoptosis. The composition containing ellagic acid as an active ingredient is provided as an intestinal microbe-improving composition and a preventive and therapeutic preparation for alcoholic fatty liver.

A method for controlling or reversing the alcohol intake in the non-alcohol dependent individual both before or during their alcohol imbibing. This is accomplished by self-administering a spray directed into sensitive mucosal vein endings of the individual. There are at least three technologies to accomplish the above noted task. The first one is a nasal spray which is directed into the nasal passage. The second spray is directed into the mouth of the individual so that the medication can be absorbed by the buccal mucosal membrane in the mouth of the individual. The third medicated spray technology is pulmonary inhaler aerosolization which is absorbed in the tissues of the lung. All of the above noted sprays by-pass the liver and the intestines. The medication, Flumazenil, is the medication used in any of these sprays to accomplish the desired effect.

Provided is a drug for improving pancreatic function and / or liver function having been worsened by usual life habits. A liver function improving agent and / or a pancreatic function improving agent, said agents comprising a liver hydrolysate as an active ingredient, for people with high-fat diet and alcohol intake.

The invention discloses a comprehensive evaluation method of drunkenness degree after drinking of wines, which comprises the following steps: observing changes of drunkenness indexes such as incubation period, intoxication period, drunkenness rate, death rate, unawake rate and the like of single drunkenness of mice under the same alcohol intake by comparison, quantifying qualitative indexes to calculate drunkenness degree values, and qualitatively reflecting the drunkenness degree; secondly, comparing and analyzing in-vivo ethanol content change conditions of different drunk wine bodies underthe same alcohol intake, quantifying quantitative indexes to calculate an alcohol metabolism value, and quantitatively investigating the influence of alcohol absorption or metabolism conditions in thedrunk body on the drunkenness degree. According to the method, qualitative and quantitative aspects are integrated, and the drunkenness degrees of different wine bodies after drinking are more comprehensively compared, analyzed and evaluated.

The invention discloses rhizoma atractylodis macrocephalae polysaccharide capable of resisting alcoholic liver injury and a preparation method of the rhizoma atractylodis macrocephalae polysaccharide. The rhizoma atractylodis macrocephalae polysaccharide is prepared from glucose, mannose and xylose in a molar ratio of 6.8:3.0:1. The molecular weight of the rhizoma atractylodis macrocephalae polysaccharide is 5465 Da. The primary structure of the rhizoma atractylodis macrocephalae polysaccharide is [beta]Xylp-[(1->3)-[beta]Xylp]6-(1->6)-[alpha]Glcp-[(1->4)-[alpha]Glcp]40-[(1->2)-[alpha]Manp]12. Experimental results show that the rhizoma atractylodis macrocephalae polysaccharide has an obvious protection effect on acute alcoholic liver injury of mice, can obviously inhibit the increase of the activity of AST, ALT and TG in serum caused by the acute alcoholic liver injury, effectively inhibits the increase of liver indexes, the increase of MDA content in the liver and the reduction of the activity of SOD and GSH-Px caused by alcohol intake, and can effectively relieve the alcoholic liver injury symptom of the mouse, and it is shown that the rhizoma atractylodis macrocephalae polysaccharide has a relatively good protection effect on the ethanol-induced acute liver injury of the mouse.

The invention discloses a traditional Chinese medicine composition capable of rapidly dispelling the effects of alcohol. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 15 parts of radix puerariae, 6 to 8 parts of radix notoginseng, 15 to 20 parts of green beans, 5 to 10 parts of brown sugar, 10 to 12 parts of orange peel, 2 to 5 parts of endothelium corneum gigeriae galli, and 6 to 9 parts of fructus gardeniae. The composition can rapidly dispel the effects of alcohol, can takes effect rapidly, is small in harm to the human body, and is suitable for being used after a great amount of alcohol intake of the human body.

The invention relates to the field of biological medicines, in particular to an application of lactobacillus to preparation of a product for preventing and / or treating weight loss caused by alcohol intake. According to the application disclosed by the invention, before, after or during alcohol intake, lactobacillus, especially lactobacillus plantarum can be continuously administrated to relieve the condition of weight loss caused by alcohol. In addition, when the lactobacillus and other medicaments that are capable of preventing and / or treating the body damages caused by alcohol are used together, the condition of the weight loss can be improved more effectively.

An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.

The invention relates to a cold-start device applied to an alcohol-based fuel system and further provides the alcohol-based fuel system. The cold-start device comprises a cold-start oil tank, an oil gas generator, a temperature sensor and an electromagnetic valve; the cold-start oil tank supplies oil to an engine through a fuel oil rail; the electromagnetic valve is arranged on the fuel oil rail and used for controlling connecting and disconnecting of the fuel oil rail; the oil gas generator is arranged in the cold-start oil tank; the temperature sensor is used for sensing the temperature of the engine; and when the temperature sensed by the temperature sensor is lower than a first preset value, the temperature sensor controls the electromagnetic valve to be opened, and oil gas in the cold-start oil tank is sucked in by the engine to be mixed with alcohol-based fuel for burning, and when the temperature sensed by the temperature sensor is higher than a second preset value, the temperature sensor controls the electromagnetic valve to be closed. According to the alcohol-based fuel system and the cold-start device of the alcohol-based fuel system, an oil pump is not needed in cold start, the product is the oil gas, and cold-start mode switching is not needed; and according to the alcohol-based fuel system and the cold-start device of the alcohol-based fuel system, the engine can be started normally at the low temperature.

The invention belongs to the technical field of bioassay, and discloses a vascular dementia model of the influence of hemopoietin on choline acetyl transferase. A big mouse not showing the symptom ofthe lesion of the vascular dementia model is subjected to water deprivation and is allowed to continuously and naturally drink a 1%-4% methyl alcohol aqueous solution for 60-240 days, or banana tasteflavouring agent capable of making the big mouse generate preference is further dissolved in the methyl alcohol aqueous solution, the methyl alcohol intake of the big mouse per day is controlled at 1mg / kg to 2 mg / kg, and the vascular dementia model capable of showing the influence of hemopoietin on choline acetyl transferase can be obtained; after the vascular dementia model the influence of hemopoietin on choline acetyl transferase is obtained, the dementia type disorder and the like are evaluated. The acting mechanism of ChAT in EPO for improving the VaD big mouse recognition disorder isdetermined.

The invention discloses an alcohol detector, which comprises the front of the alcohol detector, the back of the alcohol detector, an air inlet, a display screen, a detection switch, an air outlet, a horn, a battery, an electric shock head, a voice device, an alarm lamp, and a key chain. The air inlet, the display screen, the detection switch, the horn and the alarm light are placed on the outer surface of the front of the alcohol detector, and the air outlet and the electric shock head are placed on the alcohol detector. The outer surface of the back of the alcohol detector, the battery and the voice device are placed inside between the front of the alcohol detector and the back of the alcohol detector, and the key chain is placed between the front of the alcohol detector and the alcohol detector The outer surface between the backs of the meter. The present invention is equipped with a voice device and comes with a memory card. When the alcohol content in the human body exceeds the standard, the alarm light will light up, and the voice stored in the voice device will be played, so that drunk people can quickly wake up.

The invention relates to the field of detection articles, in particular to an alcohol controller and an application method for the same. The alcohol controller comprises an alcohol detector, a process and an authenticator; the authenticator is used for judging whether a user sitting on a driver seat is a user corresponding to information stored in the authenticator in advance, and transmits an authentication signal to the processor if the user sitting on the driver seat is the user corresponding to the information stored in the authenticator in advance; the processor receives the authentication signal and controls starting of the alcohol detector according to the authentication signal; after being started, the alcohol detector detects the alcohol intake of the user, judges whether the alcohol intake of the user exceeds a preset value or not, and transmits a detection signal to the processor; and the processor is further connected with a starting circuit of an automobile, is used for receiving the detection signal and controls opening of the starting circuit according to the detection signal. The alcohol controller and the application method have the advantages that the person sitting on the driver seat is authenticated by the authenticator before the alcohol detector is used for detecting the alcohol intake of the user, so that the driver is authenticated, and is passively subjected to alcohol detection.

The invention discloses a production process of slightly fermented fruit juice, and relates to the technical field of fruit juice processing, and the production process of the slightly fermented fruit juice comprises the following steps: raw material preparation, preparing newly picked fruits prepared, washing and then airing, after water on the surfaces of the fruits is aired, putting the fruits into a crusher to be crushed, and taking out all pulp, peel and fruit juice generated by crushing for later use; and treatment of a container: selecting a heatable sealed container as a fermentation container, placing an alcohol concentration monitor in the fermentation container, and spraying 75% ethanol or washing the interior of the container with 0.01% potassium permanganate liquid. According to the production process, when the alcohol concentration in the fermentation container reaches 0.3%, the fermentation container is heated, so that saccharomycetes in the container are inactivated, it is guaranteed that the final fruit juice contains low alcohol content, the original mellow taste of fruits is reserved, meanwhile, a small amount of alcohol intake can promote blood circulation of a human body, and the beneficial effects of the fruit juice are enhanced.