The invention discloses a production process for cotton paper, which comprises the following steps of: digesting long fibered wood pulp by using a hydraulic breaker, and adding chemical aids to prepare primary pulp; serially connecting a fluted disc type deflaker and a fiberizer, pulping in a semi-cohesive state at low current, wherein the pulping concentration of the fiberizer is 4.2 to 5.5 percent and the pulping ampere is 46 to 58A; compounding the pulp after the pulping is finished, adding 1 percent of brightener, filtering with a 90-mesh screen, and uniformly compounding with the pulp; and performing papermaking on the mixed pulp, drying, reeling by using a re-reeling machine, detecting broken paper in the drying and reeling procedures, digesting and defibering the detected broken paper, and refluxing the broken paper to the pulp compounding procedure. The cotton paper prepared by the process has the advantages of uniform fibrous tissues, flat and smooth paper surface and small aspect ratio.