The invention discloses a full-automatic integrated air column bag packaging machine. The full-automatic integrated air column bag packaging machine comprises a rack, wherein a winding roller and a redirection roller are rotatably installed on the top of the rack, the winding roller is positioned on the front side of the redirection roller, the winding roller is parallel to the redirection roller, an air column bag clamp is installed on the lower part of the rack, the end of an air column bag bypasses the redirection roller and then is clamped by the air column bag clamp, a block pushing mechanism is installed on the front side of the rack, both the winding roller and the redirection roller are positioned above the block pushing mechanism, the block pushing mechanism is positioned above the air column bag clamp, a vertical pressing heat sealing device and a transverse pressing heat sealing cutting device are installed on the rear side of the rack, and the transverse pressing heat sealing cutting device is positioned between the redirection roller and the vertical pressing heat sealing device. The full-automatic integrated air column bag packaging machine has the advantages of reasonable structural design, rapidity and convenience in packaging, high packaging efficiency, stability and reliability in block pushing, attractive appearance and environmental friendliness of packaging materials, the problem of heavy workload caused by manual packaging is solved, an accurate positioning function is realized, and the system safety is increased.