30results about How to "Reduce the risk of non-conformity" patented technology

The invention discloses a method for detecting the esterification rate of heparin benzyl ester in a production process of enoxaparin sodium, belonging to the field of biological medicines. According to the method, by adopting a reversed phase liquid chromatography method and using a high-efficiency liquid chromatograph with an ultraviolet detector, phenylcarbinol generated in a process that heparin benzyl ester drops in an alkaline environment is quantitatively detected and the esterification rate of the heparin benzyl ester is reflected, thus the purpose of controlling the quality of the finished product enoxaparin sodium is reached. Compared with the prior art, the method is capable of simply, rapidly and accurately monitoring the esterification rate of the heparin benzyl ester, thereby reducing the unqualified risk of the finished product enoxaparin sodium and the production cost of enterprises, and achieving great good popularization and application value.

The invention relates to the field of medical treatment of oral cavity, in particular to a looped gingival retraction device assembly. The looped gingival retraction device assembly comprises a gingival wire fixing hoop, a gingival wire fixing pipe and a gingival wire fixing plate, wherein both ends of the gingival wire fixing hoop extend down to form fixing jaws, and each fixing jaw is retractedin an arc shape; a gingival wire fixing clip is arranged at one side of the gingival wire fixing pipe, and the gingival wire fixing pipe is fixedly arranged at the end surface of the corresponding fixing jaw. The looped gingival retraction device assembly has the advantage that the gingival wire is firmly pressed into gingival sulcus, so that while the falling of the gingival wire is prevented, the damage to the teeth and gingival is avoided.

The invention discloses a method for detecting the esterification rate of heparin benzyl ester in a production process of enoxaparin sodium, belonging to the field of biological medicines. According to the method, by adopting a reversed phase liquid chromatography method and using a high-efficiency liquid chromatograph with an ultraviolet detector, phenylcarbinol generated in a process that heparin benzyl ester drops in an alkaline environment is quantitatively detected and the esterification rate of the heparin benzyl ester is reflected, thus the purpose of controlling the quality of the finished product enoxaparin sodium is reached. Compared with the prior art, the method is capable of simply, rapidly and accurately monitoring the esterification rate of the heparin benzyl ester, thereby reducing the unqualified risk of the finished product enoxaparin sodium and the production cost of enterprises, and achieving great good popularization and application value.

The invention relates to a method for measuring a depth of a roller body hardening layer. The method comprises the following steps of: 1) selecting a test roller; 2) processing a temperature measurement hole; 3) burying a thermocouple; 4) acquiring temperature; and 5) analyzing a test result. The method has the characteristics that the test data is detailed, the test period is short, the process time of a test is 4-5 hours or so, the test cost is low, a test material and equipment can be reused, the credibility of the test result is high and the like.

The invention discloses a device and a method for interchangeability of aircraft component assembly parts in complex structures. The device comprises two test blocks, wherein handles is arranged on the test blocks, the structures of the test blocks are identical to the structure at a coordination area position of the aircraft assembling parts, a view window is arranged at a shield position of an assembling matching area; the method comprises the following steps of uniformly coating grinding pigment with color on the surfaces of the test blocks of the aircraft parts and corresponding matching surfaces in the aircraft parts, placing the test blocks in the aircraft parts, testing an inner assembling surface of the aircraft parts, finishing an assembling interference position, and finally satisfying the optional interchangeable assembly of the aircraft parts. The interchangeability of aircraft component assembly parts in complex structures is realized, the assembling efficiency of the aircraft parts is improved, the risk that the aircraft assembly is unqualified is reduced, the cost is low and the practicability is good.

The invention relates to the field of medical treatment of oral cavity, in particular to a looped gingival retraction device assembly. The looped gingival retraction device assembly comprises a gingival wire fixing hoop, a gingival wire fixing pipe and a gingival wire fixing plate, wherein both ends of the gingival wire fixing hoop extend down to form fixing jaws, and each fixing jaw is retractedin an arc shape; a gingival wire fixing clip is arranged at one side of the gingival wire fixing pipe, and the gingival wire fixing pipe is fixedly arranged at the end surface of the corresponding fixing jaw. The looped gingival retraction device assembly has the advantage that the gingival wire is firmly pressed into gingival sulcus, so that while the falling of the gingival wire is prevented, the damage to the teeth and gingival is avoided.

The present invention discloses a rubber pipe vulcanization mold core and a rubber pipe vulcanization mold, and relates to the technical field of molds. The rubber pipe vulcanization mold core comprises a fixation portion and a molding portion, wherein the fixation portion and the molding portion are connected and fixed, a ventilation hole is arranged inside the mold core along an axial line position, the ventilation hole part positioned on the fixation portion is a blind hole, the ventilation hole part positioned on the molding portion is a through hole, at least a gas inlet hole is arranged on the fixation portion of the mold core, and the outer surface of the fixation portion and the ventilation hole are communicated through the gas inlet hole. The present invention further discloses a mold matched with the mold core, wherein the mold comprises the mold core and a mold sleeve, and the mold sleeve is sleeved on both ends of the mold core. With the rubber pipe vulcanization mold core and the rubber pipe vulcanization mold of the present invention, the problems of low product qualification rate, waste of labor and waste of materials of the existing rubber pipe vulcanization mold core production are solved.

The invention concerns a method for manufacturing a spring (1) for a spring brake (14), comprising a shaping and cutting step f) comprising the following sub-steps: - f1) shaping a raw wire into a coil with a plurality of raw turns, the raw wire having: raw portions that extend from the end of the raw wire over at least one raw turn, and an intermediate portion between the raw portions, - f2) separating the first raw portion and the second raw portion of the raw wire by cutting, after implementing sub-step f1), and - f3) shaping a first tab (5), at a first end of the intermediate portion, after sub-step f1), and - f4) shaping a second tab (7), at a second end of the intermediate portion opposite the first end, after sub-step f1).

The invention discloses an automatic steam curing system of a pipe segment production line. The automatic steam curing system comprises a control system and a box body erected at the periphery of a conveyor belt; the box body is divided into a heating chamber, a constant-temperature chamber and a cooling chamber by four openable heat-insulating layers along the motion direction of the conveyor belt; and the heating chamber, the constant-temperature chamber and the cooling chamber are internally and respectively provided with a temperature sensor; the heating chamber and the constant-temperature chamber are further communicated with a steam pipeline which is provided with a steam valve; and the control system is electrically connected with the temperature sensors, the steam valve and the conveyor belt. With adoption of the automatic steam curing system of the pipe segment production line disclosed by the invention, the automatic steam curing of the pipe segment production line is realized; and the automatic steam curing system has the features of high degree of automation, energy-saving and consumption-reducing performances, strong traceability and high efficiency of pipe segment production.

The invention provides an extraction method suitable for water-soluble heat-sensitive ingredients of traditional Chinese medicines. The extraction method suitable for water-soluble heat-sensitive ingredients of traditional Chinese medicines comprises the following step: adding water at the temperature of 95-100 DEG C in medicinal materials to soak and extract the medicinal materials, wherein soaking time lasts for 10-30 min, the extraction times are 3-5 times, and the environment temperature is 20-30 DEG C. In the provided extraction method, boiling water at the temperature of 95-100 DEG C isadopted to repeatedly soak and extract the traditional Chinese medicinal materials, by strictly control over the soaking time and the extraction times, it ensures that effective constituents are leached fully, and loss of the heat-sensitive ingredients is reduced. The used boiling water can further kill microorganisms in water and an extracting solution, the storage time of the extracting solutionis prolonged, the risks of unqualified bacterial inspection of finished products are reduced, meanwhile, soluble substances of water-soluble impurities in the medicinal materials are further reduced,the content of the effective constituents is increased, and the dosage of a patient is reduced.

The invention discloses a method for detecting the content of boron in a dalteparin sodium production process, belonging to the field of biological medicines. The method disclosed by the invention comprises the following steps of: preparing a solution at first, detecting the corresponding intensity of boron in the solution by utilizing an inductively coupled ion spectrometer, and finally, processing data to obtain the content of boron in the dalteparin sodium production process. The method for detecting the content of boron in the dalteparin sodium production process disclosed by the invention is capable of detecting the content of boron simply, rapidly and accurately; therefore, the problem of unqualified finished products due to the fact that the content of boron cannot be detected in the dalteparin sodium production process is overcome; the product qualification rate can be effectively increased; the unqualified risk of heparin sodium products and the production cost of enterprises are greatly reduced; simultaneously, the drug use risk of people is greatly reduced; furthermore, the method is simple to operate; and thus, industrial popularization and application are facilitated.

The invention discloses a grenade quality detection method and system based on visual recognition. The three-dimensional model of the projectile body of the grenade is reconstructed in the computer through three-dimensional scanning, and the engraved groove formed by each groove line is quickly calculated according to the three-dimensional model of the projectile body. The center of gravity on the circumscribed circle of the groove surface is used to calculate the error angle between its tangent vector and the circumscribed circle tangent vector; when the number of unqualified detection areas in the projectile detection area of ​​all grenades exceeds the tolerance threshold, the grenade is marked The projectile is a substandard product, otherwise it is a qualified product, so that the products with a large error angle are screened out, and the products with a small error angle are screened out to help improve the stability of the projectile structure and reduce the unevenness of the projectile body and the uneven thickness of the projectile. The product leads to the risk of being unqualified and reduces the probability of projectile instability. The invention is applied to the detection of grenade projectile products.

The invention discloses a solvent system capable of effectively dissolving ornidazole or left-ornidazole and its application. The active ingredient is ornidazole or left-ornidazole, and the solvent system is an organic solvent mixed with short-chain polyethylene glycol and propylene glycol; The short-chain polyethylene glycol is preferably polyethylene glycol 300 or / and polyethylene glycol 400. The solvent system can be used in the preparation of ornidazole injection or left-ornidazole injection. The present invention has technical advantages that cannot be achieved by the prior art. The preparation of ornidazole injection or left-ornidazole injection has the advantages of simpler prescription, safer production, more stable preparation, less solvent content, and impurities (especially genes) Toxic impurities) content is lower, low temperature is not easy to crystallize, low incidence of phlebitis, no irritation of low pH infusion, more suitable for patients with sensitive disulfiram reactions, etc., to ensure safer clinical medication and drug compliance of patients better.

The invention relates to a quality control method of an almagate suspension, and the method is easy and convenient to operate. The method comprises the steps of (1), quality control of a suspension phase: the sedimentation volume ratio F is measured, and the F should be larger than or equal to 95.0%; (2) quality control before filling: absorption of acid is measured, the consumption of each 1g of almagate suspension on a hydrochloric acid volumetric solution (0.1 mol / L) should be larger than or equal to 23.0 mL; viscosity is measured, and the measured viscosity coefficient eta should be 1,200+-400 mPa.s. The preparation process of the almagate suspension is subjected to quality control with the method, preventive measures are taken in advance, the rick of unqualified finished products is reduced greatly, and clinical medicine is ensured to be safe and effective.

The invention relates to a quick alignment unit of a numerical control machining datum for irregular-appearance rough materials. A support plate is disposed on a milling fixture, a positioning device is disposed in the lengthwise direction of the support plate, a quick alignment device is disposed at one width-wise end of the support plate, a press plate is disposed at the other width-wise end of the support plate, and the end of the press plate is disposed above the support plate. Both the positioning device and the press plate are movably connected with the milling fixture. The quick alignment device comprises a quick aligner, two cylindrical positioning pins and a plurality of tapered alignment pins. The tapered alignment pins are disposed on the upper bent surface of the quick aligner. Bottom tips of the tapered alignment pins are evenly distributed on an outline, to be machined, of a casting to be machined. Two cylindrical positioning pins are arranged on the lower bent surface of the quick aligner and fit two through holes at the corresponding positions of the milling fixture. A round tool-setting block is disposed at a certain fixed position of the milling fixture. The quick alignment unit has the advantages that the numerical control datum can be quickly aligned by the alignment unit directly through any scribed irregular shapes as datum references.

The invention provides a half-shaft tooth-to-teeth detection and tightening center screw equipment, which includes a clamping mechanism and a testing mechanism, wherein the clamping mechanism includes a clamping and anti-torsion mechanism, a brake disc clamping claw cylinder mechanism, and a half-shaft centering clamp Jaw cylinder and compression cylinder mechanism; testing mechanism includes testing servo tightening shaft, central screw servo tightening shaft, hollow gear box and pneumatic spring. The embodiment of the invention can reduce the risk of unqualified parts caused by the teeth not meshing in the production line, not only improves the production line beat, but also improves the economic benefits of the automobile enterprise; in addition, the semi-axis tooth-to-tooth detection and tightening center screw equipment is installed on the pallet production line , to achieve fully automatic testing and central screw tightening, which is more efficient, faster and safer than traditional assembly line operations.

A side thruster for aircraft thin-wall part processing comprises a guide block, a pressing plate and a clamp plate. The guide block is located above the clamp plate, the pressing plate is arranged above the guide block, the end of the pressing plate is of a zigzag shape, a first bolt passes through a waist-shaped groove of the pressing plate to be connected with the guide block in threaded manner, a third bolt passes through the waist-shaped grooves of the pressing plate and the guide block to be connected with the clamp plate in a threaded manner, a second bolt passes through a wedge block and the pressing plate to be connected with the guide block in a threaded manner, a spring washer is arranged between the first bolt and the waste-shaped groove of the pressing plate, and an angle gasket is arranged between the third bolt and the waste-shaped groove of the pressing plate. The positioning method includes: mounting an aircraft thin-wall part on the clamp plate, moving the side thruster to allow the zigzag-shaped surface of the end of the pressing plate to be in appearance contact with the aircraft thin-wall part, and respectively fixing the side thrusters on the appearance surface of the thin-wall part. By the side thruster, clamping reliability during numerical-control processing of the aircraft thin-wall part is improved, clamping deformation due to extrusion of the aircraft thin-wall part is avoided, risk of unqualified products is reduced, and practicability is good.

The invention discloses a solvent system capable of effectively dissolving ornidazole or left-ornidazole and an injection thereof, the active ingredient is ornidazole or left-ornidazole, and the solvent system is a mixture of short-chain polyethylene glycol and ethanol The organic solvent of short-chain polyethylene glycol is preferably polyethylene glycol 300 or / and polyethylene glycol 400. The mixed mass fraction ratio of short-chain polyethylene glycol and ethanol in the solvent system is 30-100:0-70. The present invention has technical advantages that cannot be achieved by the prior art. The ornidazole injection or left-ornidazole injection has the advantages of simpler prescription, safer production, more stable preparation, less solvent content, and impurities (especially genotoxic impurities). ) content is lower, the number of impurities is less, low temperature is not easy to crystallize, the incidence of phlebitis is low, no low pH infusion irritation, no propylene glycol and other unique preparation advantages ensure safer clinical medication and better drug compliance of patients.