The invention discloses a large dynamic range semi-floating gate image sensor, comprising a pixel array, a current processing column level circuit and a voltage processing column level circuit, the pixel array includes a plurality of pixels, each of the pixels includes a semi-floating gate A transistor and a first voltage conversion circuit, the first voltage conversion circuit is used to convert the current signal output by the semi-floating gate transistor into a voltage signal, and sample and output the reset voltage and the signal voltage respectively, so as to realize pixel-level correlated double sampling, reduce read noise. In the present invention, a voltage column-level processing circuit is added to the semi-floating gate image sensor, and a voltage conversion circuit is added to each pixel, so that the image sensor can take into account the large full well charge capacity and high conversion gain, and can be used in high background and low background. It can be imaged at any time, which greatly expands the application range of the semi-floating gate image sensor; in addition, binning between pixels can also be realized, which further expands the dynamic range of the image sensor.