33results about How to "Prevent rebleeding" patented technology

The invention discloses an absorbable and degradable biocompatible hemostatic material and a preparation method thereof. The hemostatic material is prepared by crosslinking fish collagen and chitosan by virtue of a plasticizer, wherein the weight ratio of the fish collagen to the chitosan to the plasticizer is (1-2):(2-4):(0.1-0.6), and the degree of deacetylation of the chitosan is not less than 80%. The appearance of the hemostatic material is in the shape of white sponge flake with elasticity. The hemostatic sponge provided by the invention can be applied to hemostasis in various operations of the surgical department, the department of stomatology, the department of burn and the department of plastic surgery, is quick in hemostatic effect and good in biocompatibility, does not have immunogenicity, is aseptic, nontoxic and nonirritant, and can be absorbed in vivo. The absorbable and degradable biocompatible hemostatic material is better in safety compared with a hemostatic material prepared from terrestrial animal collagen, and is a more ideal hemostatic material.

The invention relates to omeprazole sodium and a preparation method, and in particular relates to a method for preparing omeprazole or a salt thereof. The method comprises the following steps of: (1) reacting 2-chlorinated methyl-3,5-dimethyl-4-methoxypyridine or a salt thereof and 2-mercapto-5-methoxy-1H-benzimidazole to generate 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridine-2-yl)methylmercapto]-1H-benzimidazole; and (2) oxidizing 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridine-2-yl)methylmercapto]-1H-benzimidazole to generate omeprazole. The invention further relates to omeprazole prepared by the invention or a sodium salt thereof. A product prepared by the method has high purity.

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases, which is prepared from the following bulk drugs: leech, lumbricus, scorpio and pseudo-ginseng. The traditional Chinese medicine composition disclosed by the invention accords with the theories of traditional Chinese medicine pharmacology of removing stasis, promoting new and self-quenching wind through blood circulation; in addition, by utilizing the traditional Chinese medicine composition formula, the traditional Chinese medicine composition disclosed by the invention is capable of promoting circulation, removing stasis, removing blood stasis, clearing hematoma, stopping rehaemorrhagia, reducing intracranial pressure, eliminating encephaledema, adjusting whole-body blood, resisting stress reaction and improving microcirculation and has the unique curative effects to perennial serious hypertension, cerebral hemorrhage, stroke, coronary heart disease and cerebral thrombosis.

The invention discloses a hemostat and a preparation method thereof. A finished product liquor per 1000 g comprises 10-16 g of termite fungus garden composition powder, 4-6 g of collagen, 0.02-0.04 g of ternary acid, 7-9 g of bactericidal agent and the balance of water. The invention has the advantages that the termite fungus garden composition powder containing rich nutrient contents is utilizedin the prescription, the functions of detumescence, convergence and hemostasis are achieved, meanwhile the weak body is tonified without any side effect; the collagen has very strong affinity with different cells, and also has ideal affinity with growth factors which play a key role in the process of wound healing, after blood coagulation, the collagen can also prevent bleeding again through stimulating the regeneration and the repair of tissues. The hemostat is not fastidious about the using object, has fast hemostasis effect, excellent functions of anti-inflammatory, detumescence and acesodyne without toxic or side effect, or untoward reaction of stimulations. The preparation method has less technical steps and non-rigorous preparation condition, and can be suitable for the industrial mass production.

The invention relates to pantoprazole sodium freeze-dried powder injection, in particular to freeze-dried powder injection which contains pantoprazole sodium, mannitol, citric acid and optional pH regulator. The invention further relates to a method for preparing the pantoprazole sodium freeze-dried powder injection disclosed by the invention. The pantoprazole sodium freeze-dried powder injection disclosed by the invention can be used for treating stomach diseases and has anticipated good properties.

The invention relates to an omeprazole sodium freeze drying powder injection pharmaceutical composition for injection. In particular, on the one hand, the invention relates to a freeze drying powder injection pharmaceutical composition which comprises omeprazole sodium, ethylenediamine tetraacetic acid disodium salt and an optional acidifying or alkalizing agent; on the other hand, the invention further relates to a method for preparing the omeprazole sodium freeze drying powder injection pharmaceutical composition for injection. The method is a conventional preparation method of the omeprazole sodium freeze drying powder injection pharmaceutical composition for injection. The omeprazole sodium freeze drying powder injection pharmaceutical composition for injection provided by the invention can be used for treating gastropathy and has an anticipated good property. For example, the omeprazole sodium freeze drying powder injection pharmaceutical composition for injection not only has excellent physical and chemical stabilities, but also has an excellent biological property.

The invention relates to an omeprazole sodium freeze-dried powder injection for injection. Specifically, the invention relates to the freeze-dried powder injection containing omeprazole sodium, disodium edetate and arbitrarily selected pH regulator. The omeprazole sodium freeze-dried powder injection for injection, disclosed by the invention, can be used for treating stomach diseases and further has exciting good properties.

The invention discloses a woundplast not sticking to a wound, which comprises a strip-shaped medical adhesive tape, an officinal cotton cushion soaked with antiphlogistic astringent is adhered on part of the medical adhesive tape and two plastic protective films covering the upper part of the officinal cotton cushion, wherein an antibacterial moisture conduction gauze woven from special-shaped section antibacterial fiber covers the officinal cotton cushion under the protective films; the length of the antibacterial moisture conduction gauze is shorter than that of the medical adhesive tape but longer than that of the officinal cotton cushion; and two ends of the antibacterial moisture conduction gauze are adhered on the medical adhesive tape. According to the invention, the special-shaped section antibacterial fiber is adopted to weave the antibacterial moisture conduction gauze, and the antibacterial moisture conduction gauze is used to cover the officinal cotton cushion with excellent hydroscopic property. When in use, the antibacterial moisture conduction gauze is in direct contact with the wound, the medicine component in the officinal cotton cushion acts on the wound through the antibacterial moisture conduction gauze, and the blood effluent from the wound is absorbed by the cotton cushion with high hydroscopic property through the gauze. When the blood solidifies, the used woundplast is easy to be separated from the wound due to less blood crusted on the wound surface, so that a second hurt to the wound is avoided.

The invention discloses an anti-collision device for nursing patients suffering from a bleeding tendency. The device comprises a vertically arranged fixed base, a vertically arranged fixed groove is formed in the middle of the bottom of the fixed base, an air bag is in sealing connection with one side of the fixed base, an air delivery pipe is arranged on one side of the bottom of the air bag, a valve is arranged on the air delivery pipe, a vertically arranged movable plate is fixed to the inner wall of the side, away from the fixed base, in the air bag, three buffer components are arranged between the fixed base and the movable plate, each buffer component comprises two horizontally arranged movable rods which are crosswise arranged, sliding blocks are hinged to the two ends of the movable rods, three horizontally arranged sliding grooves are formed in the side walls of the sides, close to each other, of the fixed base and the movable plate, and the sliding blocks are slidably connected into the sliding grooves. By means of the device, a sickbed is effectively protected, and the phenomenon that when external impact is too large, great harm is caused to the patients, and then wounds of the patients bleed again is prevented, the anti-collision effect is good, the safety is high, and practicability is high.

The invention discloses a composition for treating lumbago and a preparation method of the composition, and aims at providing a traditional Chinese medicine composition which is capable of activating blood, dredging collaterals, relieving swelling and pain and effectively treating lumbago, and is small in side effect. According to the technical main points, the composition is prepared from the following components in parts by weight: 50-100 parts of rose mallow root whole plants, 50-100 parts of mirabilis jalapa whole plants, 30-100 parts of impatiens balsamina whole plants, 100-150 parts of paederia scandens whole plants, 30-100 parts of sansevieria trifasciata leaf whole plants and 10-30 parts of ginger. The composition belongs to the technical field of the traditional Chinese medicine.

The invention relates to omeprazole sodium and a preparation method, and in particular relates to a method for preparing omeprazole or a salt thereof. The method comprises the following steps of: (1) reacting 2-chlorinated methyl-3,5-dimethyl-4-methoxypyridine or a salt thereof and 2-mercapto-5-methoxy-1H-benzimidazole to generate 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridine-2-yl)methylmercapto]-1H-benzimidazole; and (2) oxidizing 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridine-2-yl)methylmercapto]-1H-benzimidazole to generate omeprazole. The invention further relates to omeprazole prepared by the invention or a sodium salt thereof. A product prepared by the method has high purity.

The invention discloses a composition for treating lumbago and a preparation method of the composition, and aims at providing a traditional Chinese medicine composition which is capable of activating blood, dredging collaterals, relieving swelling and pain and effectively treating lumbago, and is small in side effect. According to the technical main points, the composition is prepared from the following components in parts by weight: 50-100 parts of rose mallow root whole plants, 50-100 parts of mirabilis jalapa whole plants, 30-100 parts of impatiens balsamina whole plants, 100-150 parts of paederia scandens whole plants, 30-100 parts of sansevieria trifasciata leaf whole plants and 10-30 parts of ginger. The composition belongs to the technical field of the traditional Chinese medicine.

The invention relates to a pantoprazole sodium freeze-dried powder injection pharmaceutical composition and a preparation method thereof, and particularly relates to a freeze-dried powder injection. The freeze-dried powder injection comprises pantoprazole sodium and medicinal auxiliary materials such as mannitol. The freeze-dried powder injection is the third generation of proton pump inhibitor; and the pantoprazole sodium is a parietal cell proton pump inhibitor, and has relatively good selectivity on H+ and K+- ATP enzymes. The invention relates to a method for preparing the pantoprazole sodium freeze-dried powder injection. The pantoprazole sodium freeze-dried powder injection can be used for treating a gastric disease, and has excellent pharmaceutical properties shown in the description.

The invention discloses a preparation method of a medical alginic acid hemostatic material.The preparation method comprises the steps that alginic acid is dissolved in a sodium hydroxide alkaline solution with the concentration of 0.05-0.15 mol / L, and a sodium alginate solution with the mass percentage concentration of 2-5% is prepared; the sodium alginate solution is added into a phosphate saturated aqueous solution to obtain a mixed solution, the pH value of the mixed solution is adjusted to be 5-9, and aging is performed; Carbomer is dissolved in distilled water to be swelled to obtain a Carbomer solution, wherein the mass-volume ratio of the Carbomer solution to the distilled water is 1:(10-20) g / mL; the mixed solution and the Carbomer solution are mixed according to the volume ratio of (3-5):1, filtration and vacuum drying are performed, and therefore the alginate / Carbomer / phosphate hemostatic material is obtained.The technology is simple, the production cost is low, the final product is stored after being dried, and the storage condition is relatively easy to meet.

The invention relates to the technical field of medical hemostatic patches, and particularly relates to a porcine-derived fibrin-electrostatic spinning nanofiber antibacterial hemostatic patch and a preparation method thereof. The preparation method comprises the following steps of: preparing a porcine-derived fibrinogen and thrombin blended suspension, then spraying or soaking the blended suspension on thes urface of a silk fibroin nanofiber film prepared by an electrostatic spinning technology, and drying to prepare the porcine-derived fibrin hemostatic absorbable patch for postoperative hemostasis. The patch has an excellent hemostatic effect, combines a fibrin thrombin hemostatic mechanism with the mechanical properties of the antibacterial silk fibroin film to enhance the hemostatic effect, and is natural and absorbable, so that the hemostatic effect is improved, and the fibrinogen and thrombin are combined into one, four components are changed into a single component, preparation is not needed, and the patch can be used immediately after being opened, thereby greatly simplifying the problems of complex use and long time consumption of the existing fibrinogen adhesive; and the patch can be stored and transported at room temperature, and has significant technical, cost and clinical advantages.

The present invention discloses a preparation method of an antiphlogistic and antisticking stanching sponge. The preparation method includes the following steps: through the cross linking of polyvinyl alcohol, chitosan gel microspheres are fixed on the inner wall of a sponge, the sponge is then soaked in antiphlogistic solution and antisticking solution, and finally, the PVA / drug-loaded chitosan antiphlogistic and antisticking stanching sponge is prepared. The antiphlogistic and antisticking stanching sponge prepared by the method can be trimmed according to the size of an operative cavity inorder to be placed into the corresponding part, the pressure on the circumference is uniform, blood can be thoroughly stanched, and the injury on the mucous membrane of the operative cavity is little. The antiphlogistic and antisticking stanching sponge prepared by the method, which has good antiphlogistic, stanching and antisticking functions, biocompatibility, and mechanical and anti-oedema properties, can promote the injured tissues to have strong recovering capability, prevent rebleeding and avoid the inevitable potential virus hazard caused by glutin and animal collagen proteins, so the use safety is greatly improved, and moreover, the antiphlogistic and antisticking stanching sponge can alleviate the pain and discomfort suffered by patients. The antiphlogistic and antisticking stanching sponge is expected to substitute the import products and have remarkable social and economic benefits.

The invention provides a Chinese medicinal herbal typhonium giganteum external medicament, which comprises typhonium giganteum, paris polyphylla, cape jasmine, Chinese clematis, Chinese pine node, Chinese mugwort leaf, borneol and mint which form basic drug materials. The external medicament is prepared by crushing the basic drug materials into coarse powder, and preparing into the following three preparations according to requirements: 1, Chinese medicinal herbal typhonium giganteum damp-removing and pain-relieving ointment; 2, Chinese medicinal herbal typhonium giganteum damp-removing and pain-relieving tincture; and 3, Chinese medicinal herbal typhonium giganteum external cataplasm. When used for treating sport injury, the Chinese medicinal herbal typhonium giganteum external medicament can avoid re-bleeding of capillary vessels, has certain effect of relieving pain and diminishing swelling, and does not result in the deposition of the injured part into an old injury due to condensation; and meanwhile, the external medicament can promote the autolysis and adsorption of tissue fluid seeping from the injured part. The Chinese medicinal herbal typhonium giganteum external medicament has remarkable treatment effect to old sport injuries.

The invention discloses a traditional Chinese medicine composition for treating leukemia as well as a preparation method and a traditional Chinese medicine preparation thereof, and belongs to the field of anti-leukemia traditional Chinese medicines. The traditional Chinese medicine composition is prepared from 500-1500 parts of cornu bubali, 300-1200 parts of cornu cervi pantotrichum, 200-600 parts of hirudo, 150-400 parts of donkey-hide gelatin, 60-120 parts of centipede, 120-600 parts of American ginseng and 200-700 parts of ginseng. The preparation method of thetraditional Chinese medicinecomposition comprises the step of mixing cornu bubali powder and donkey-hide gelatin with fine powder of cornu cervi pantotrichum, hirudo, centipede, cornu bubali, American ginseng and ginseng to obtain the traditional Chinese medicine composition for treating leukemia. The traditional Chinese medicine composition disclosed by the invention has the effects of preventing bleeding, promoting a bloodregeneration function and improving the immune function, can effectively relieve symptoms of leukemia, and prolongs the lifetime of a patient. Compared with chemotherapy, the traditional Chinese medicine composition has the advantages of small side effects and low treatment cost; and clinical data shows that the total effective rate of the traditional Chinese medicine composition reaches 96.4% inleukemia treatment.

The invention discloses a traditional Chinese medicine decocted extract for treating intestinal wind and a preparation method thereof. The traditional Chinese medicine decocted extract for treating intestinal wind is prepared from, by weight, 12-14 parts of rhododendron simsii var.albiflorum, 4-8 parts of elephantopus scaber, 10-12 parts of oiltea camellia flowers, 10-14 parts of balanophora harlandii Hook.F., 9-11 parts of shrub althea flowers, 12-14 parts of hedge grease, 13-15 parts of madder roots, 8-10 parts of equisetum hiemale, 9-11 parts of fructus lonicerae, 9-13 parts of seeds of rird rapes, 5-7 parts of dianthus roots, 10-12 parts of donkey-hide gelatin, 9-11 parts of kalopanax septemlobus tree roots, 5-7 parts of bamboo juice, 12-14 parts of Bladhia primulifolia Masam. and 28-30 parts of brown sugar. The traditional Chinese medicine decocted extract for treating intestinal wind is good in curative effect and can take effects fast.

The invention discloses a method for culturing autologous hair-growing stromal stem cells for cerebral hemorrhage sequelae of a premature infant. The method comprises the following steps: 1) collecting bloody cerebrospinal fluid from a lateral ventricle of the cerebral hemorrhage premature infant; 2) centrifugally collecting cells; 3) resuspending the cells by using a neural stem cell culture medium and maintaining culture; 4) changing a half amount of the liquid in 3-5 days, digesting the cells after 6-8 days, and carrying out subculture; and 5) after passage to 3-5 generations, collecting the hair growth matrix stem cells. Through primary culture and subculture, the autologous neural stem cells of the child patient are massively amplified, then cryopreserved, recovered at a proper time and implanted into the brain of the child patient, so that the treatment effect on the cerebral hemorrhage sequelae of the premature infant can be greatly improved. The hair-growing stromal stem cells cultured by the culture method disclosed by the invention are large in amplification quantity and stable in property, and can meet the requirements of autotherapy of sick children.

The invention relates to a calcium ion exchange porous starch hemostatic material and its preparation method and application. The calcium ion exchange porous starch hemostatic material of the present invention is prepared from starch through gelatinization, emulsification, pore formation, crosslinking and calcium ion exchange, and its raw materials include: starch, oil phase, porogen, emulsifier, calcium chloride, crosslinking agent and the remainder of water. The hemostatic material is made porous by ethanol alkali method to increase its specific surface area, cross-linked to increase its structural stability, reversed-phase microemulsion technology to control its particle size distribution, and the surface is modified with calcium ions to enhance its hemostatic performance , biodegradability and biocompatibility. The calcium ion-exchanged porous starch hemostatic material provided by the present invention has rich sources of main raw materials, good safety, and no residue, and can be widely used in the hemostasis application of substantive organs in the body and irregular bleeding such as diffuse bleeding, and does not require debridement after hemostasis , the hemostatic effect can continue to the postoperative period, and it can be degraded and absorbed in the human body after the postoperative period.

The invention relates to pantoprazole sodium and a preparation method thereof, in particular to a method of preparing pantoprazole sodium. The method comprises the steps of 1) using 2-hydroxymethyl-3,4-dimethoxypyridine (II) as a start material to generate a compound of formula III under the action of a chloride; 2) subjecting the compound of formula III and 5-difluoromethoxy-2-thiol-1H-benzimidazole to condensation in the presence of an inorganic base so as to generate a compound of formula IV; 3) using an oxidant to oxidize the compound of formula IV to generate 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl-1H-benzimidazole, namely, pantoprazole; 4) allowing the obtained 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl-1H-benzimidazole to react with sodium hydroxide to generate a salt, namely, pantoprazole sodium (I); and optionally 5) refining the pantoprazole sodium. The product prepared via the method has high purity; related impurities, such as oxidation impurity, reduction impurity, decomposition impurity, have low contents.

The invention relates to pantoprazole sodium and a preparation method thereof, in particular to a method of preparing pantoprazole sodium. The method comprises the steps of 1) using 2-hydroxymethyl-3,4-dimethoxypyridine (II) as a start material to generate a compound of formula III under the action of a chloride; 2) subjecting the compound of formula III and 5-difluoromethoxy-2-thiol-1H-benzimidazole to condensation in the presence of an inorganic base so as to generate a compound of formula IV; 3) using an oxidant to oxidize the compound of formula IV to generate 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl-1H-benzimidazole, namely, pantoprazole; 4) allowing the obtained 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl-1H-benzimidazole to react with sodium hydroxide to generate a salt, namely, pantoprazole sodium (I); and optionally 5) refining the pantoprazole sodium. The product prepared via the method has high purity; related impurities, such as oxidation impurity, reduction impurity, decomposition impurity, have low contents.

The invention belongs to the field of medicines, and particularly relates to a gel preparation for treating functional uterine bleeding and application thereof. The gel preparation comprises the following active components of alvimopan or composition of alvimopan and ectoin, wherein the ratio of alvimopan to ectoin in parts by weight is 1:(3 to 5). The gel preparation has the advantages that the function of shortening the bleeding time of the functional uterine bleeding is realized by external administration or local vagina administration; when the alvimopan or the ectoin is singly used, the effect can be realized; when the alvimopan and the ectoin are jointly used, the effect is further improved.

The invention belongs to the field of medicines, and particularly relates to a gel preparation for treating functional uterine bleeding and application thereof. The gel preparation comprises the following active components of alvimopan or composition of alvimopan and ectoin, wherein the ratio of alvimopan to ectoin in parts by weight is 1:(3 to 5). The gel preparation has the advantages that the function of shortening the bleeding time of the functional uterine bleeding is realized by external administration or local vagina administration; when the alvimopan or the ectoin is singly used, the effect can be realized; when the alvimopan and the ectoin are jointly used, the effect is further improved.

The invention discloses an absorbable and degradable multipurpose biocompatible material. The raw materials of the absorbable and degradable multipurpose biocompatible material comprise chitosan, collagen and hyaluronic acid or sodium alginate in a weight ratio of (2 to 8): (0.5 to 3): (1 to 5); adding a dehydrating agent; generating hydrogel by a cross-linking reaction; and finally performing freeze-drying to prepare sponge or film. The absorbable and degradable multipurpose biocompatible material disclosed by the invention can be used as a bleeding-stopping anti-adhesion material, good in tissue adhesion, remarkable in anti-adhesion effect, capable of rapidly stopping bleeding, preventing adhesion, promoting tissue healing, preventing rebleeding, eliminating the inevitable virus hidden troubles of gelatine and animal collagen, and greatly improving safety, complete in degradation, capable of being absorbed and utilized by the body, and free of side effects on the body. The absorbable and degradable multipurpose biocompatible material can also be used as a scaffold for tissue engineering, artificial skin and the like, and good in biocompatibility, absorbability and degradability.

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases, which is prepared from the following bulk drugs: leech, lumbricus, scorpio and pseudo-ginseng. The traditional Chinese medicine composition disclosed by the invention accords with the theories of traditional Chinese medicine pharmacology of removing stasis, promoting new and self-quenching wind through blood circulation; in addition, by utilizing the traditional Chinese medicine composition formula, the traditional Chinese medicine composition disclosed by the invention is capable of promoting circulation, removing stasis, removing blood stasis, clearing hematoma, stopping rehaemorrhagia, reducing intracranial pressure, eliminating encephaledema, adjusting whole-body blood, resisting stress reaction and improving microcirculation and has the unique curative effects to perennial serious hypertension, cerebral hemorrhage, stroke, coronary heart disease and cerebral thrombosis.

The invention relates to a hemostasis device, in particular to a gingival hemostasis device for children after tooth extraction. The invention provides a gingival hemostasis device after tooth extraction for children. The gingival hemostasis device can accelerate the hemostasis speed by applying medicine. A gingival hemostasis device for children after tooth extraction comprises a handle, a first connecting block, a second connecting block, a sleeve block and the like, the first connecting block is arranged on the right side of the handle, the second connecting block is rotatably arranged on the right side of the first connecting block, and the sleeve block is arranged on the right side of the lower portion of the second connecting block. A sleeve block is arranged on a pulled part in a sleeving mode, a dentist can rotate a pressing rod so that absorbent cotton can move downwards to extrude the pulled part, the aim of stopping bleeding is achieved, after the absorbent cotton and the pressing rod are reset, a pressing disc sprays medicine to the pulled part through a medicine spraying pipe under the reset effect of a third reset spring, re-bleeding can be prevented, and the aim of stopping bleeding is achieved. The aim of quickly stopping bleeding is fulfilled.

The invention provides a preparation method of a bone hemostatic material with osteogenesis inducing activity and the bone hemostatic material prepared by the preparation method. The bone hemostatic material comprises an active bone extract accounting for 0.5-5% of the mass of the bone hemostatic material, and further comprises a dispersing agent accounting for 10-23% of the mass of the bone hemostatic material and a powder adjuvant accounting for 72.9-89.5% of the mass of the bone hemostatic material, wherein the active bone extract comprises the following components in percentage by mass: 21.3-62% of a coagulant, 19.5-53.7% of a binder, 2.7-11% of a regulator, 6.1-23.4% of an osteogenesis inducing agent and 1.4-7.5% of a bacteriostatic agent. The invention further provides the preparation method of the hemostatic material. According to the bone hemostatic material with osteogenesis inducing activity and the preparation method thereof, the bone hemostatic material has good adhesion and good hemostatic effect, can be degraded, avoids the problem that a bone wound occupies a space or is difficult to repair due to the existence of foreign matters, and has good biological safety and biocompatibility.