The invention discloses a stomach-cleaning pharmaceutical composition for the digestive system department. The stomach-cleaning pharmaceutical composition comprises, by weight, 10-20 parts of panax notoginseng, 20-35 parts of Artemisia vulgaris, 12-20 parts of Eucommia ulmoides, 8-15 parts of chrysanthemum, 15-20 parts of rhizoma chuanxiong, 23-30 parts of spica prunellae, 2-10 parts of semen cassiae, 8-15 parts of semen coicis, 8-12 parts of radix glycyrrhizae, 10-20 parts of radix ophiopogonis, 2-8 parts of Erodium stephanianum Willd, 17-22 parts of Lycopodiastrum casuarinoides, 12-15 parts of Duchesnea indica, 8-16 parts of rhizoma imperatae, 5-8 parts of Lilium brownii, 8-15 parts of caulis spatholobi, 5-10 parts of radix bupleuri, 10-16 parts of Mangnolia officinalis, 8-10 parts of Artemisia apiacea, 5-10 parts of ramulus cinnamomi, 2-6 parts of perilla stem, 10-20 parts of bitter gourd, 2-7 parts of Lonicera japonica and 5-10 parts of fructus forsythia. The stomach-cleaning pharmaceutical composition has the advantages that the stomach-cleaning pharmaceutical composition made of pure natural traditional Chinese medicine materials is reasonable in medicinal component, safe, free of side effect, definite in curative effect, low in medicine cost and capable of fast and safely cleaning the stomach, a gastric lavage agent is broken through, the stomach can be cleaned and nursed, and the later recovery of the stomach is benefited.