The invention discloses a blood-activating, pain-relieving and bone-strengthening ointment, which is an external ointment. The blood-activating, pain-relieving and bone-strengthening ointment is prepared from saffron, dragon's blood, long-noded pit viper, gastrodia elata, musk tibetene, menthol, borneol and other medicaments, and has the effects of relaxing muscles and stimulating blood circulation, relieving swelling and pains, removing stasis and mass, reunioning fractured tendons and bones, dispelling wind and eliminating dampness, warming and activating meridian, removing necrotic tissue and promoting granulation and the like. The ointment can be widely applied to the surgical department, the pediatrics department, the gynecology department and other clinical departments, can be used for treating sore pain, burning pain, sciatica, arthralgia caused by hyperosteogeny, lumbar muscle strain, oil injury of bone fracture, bone spur, arthritis, aged rheumatism, rheumatoid arthritis, lumbar disc herniation, periostitis, bone tuberculosis, osteomyelitis, tenosynovitis, ankylosing spondylitis, scapulohumeral periarthritis, spinal stenosis, mid-early femoral head necrosis, soft tissue injury or cartilage wear, or clinical common pain symptoms caused by deformed joints, muscle weakness, numb, stiffness, muscle paralysis, atrophy and other reasons.