39 results about "Mucosal Ulcer" patented technology

The present invention relates to Periplaneta Americana or its ethanol extract for the treatment of inflammation. Specifically, said inflammation includes cervical erosion, ulcerative colitis, skin ulcer, mucosal ulcer and postoperative condyloma acuminatum. Treating said disorders by Periplaneta Americana or its ethanol extract has the advantages of effectively reducing bleeding, shortering healing time, significant curative effect, no adverse reactions and low cost. Periplaneta Americana or its ethanol extract provides a new selection for the clinical treatment of cervical erosion, ulcerative colitis and postoperative condyloma acuminatum.

The present invention relates to a medicine composition for curing burn, scald, nucocutaneous ulcer and scar. Said medicine composition is formed from the Chinese medicinal materials of dahurian angelica root, calcined alum and borneol and medicinal carrier and / or excipient, and can be made into the pharmaceutically-described any one dosag form. As compared with existent ointment for curing burn and scald said invention has better effect for stopping pain, inhibiting bacteria, promoting healing of wound surface and eliminating scar.

The present invention relates to Periplaneta Americana or its ethanol extract for the treatment of inflammation. Specifically, said inflammation includes cervical erosion, ulcerative colitis, skin ulcer, mucosal ulcer and postoperative condyloma acuminatum. Treating said disorders by Periplaneta Americana or its ethanol extract has the advantages of effectively reducing bleeding, shortering healing time, significant curative effect, no adverse reactions and low cost. Periplaneta Americana or its ethanol extract provides a new selection for the clinical treatment of cervical erosion, ulcerative colitis and postoperative condyloma acuminatum.

The invention discloses an antibacterial mouthwash, which comprises the following components in parts by weight: 0.01 to 0.03 part of a honeysuckle extract, 0.01 to 0.03 part of a wild chrysanthemum extract, 0.03 to 0.06 part of a liquorice root extract, 0.04 to 0.07 part of essence, 0.005 to 0.015 part of a sweetening agent, 0.005 to 0.015 part of an acidity regulator, 0.03 to 0.06 part of vitamin C, 0.6 to 1.0 part of a bactericide, 8.5 to 14.5 parts of a humectant, 7 to 9 parts of ethanol, 0.03 to 0.08 part of borneol and the balance of deionized water. The antibacterial mouthwash has the effects of sterilizing, disinfecting and halitosis removing, has obvious effects on gingival bleeding caused by gingivitis, periodontitis and periodontitis, tooth pulp swelling and aching, and recurrent oral mucosa ulcer, and is fresh in smell and excellent in taste.

The invention discloses a traditional Chinese preparation for treating ulcers, and the traditional Chinese preparation is prepared by the following medicinal materials by weight ratio: 10-30g of Chinese gall, 8-20g of Chinese violet, 10-18g of Mongolian dandelion herb, 10-20g of figwort root, 8-15g of golden thread, 10-30g of baical skullcap root, 10-25g of vietnamese sophora root, 20-30g of natural indigo and 6-12g of borneol. The medicament is mainly used for treating oral ulcers, peptic ulcers, ulcerative colitis and other mucosal ulcer diseases, and can rapidly stop pain and astringe the ulcer surfaces, the treatment course is short, the individual differences are avoided and the treatment effects are significant. The medicament is simple in ingredients, belongs to pure traditional Chinese medicine preparations and has no toxic or side effects. The medicament powder can be effectively adsorbed on the ulcer surfaces for directly acting on focuses, the medicament effect is sustained, the adsorption of the medicament on the ulcer surfaces has not been reported in the aspect of traditional Chinese medicine theory, and the formula still belongs to the first time.

.The invention discloses a traditional Chinese medicine for treating the recurrent oral ulcer. The recurrent oral ulcer belongs to the fields of aphthae, aphthous stomatitis and the like in the traditional Chinese medicinal science, and the clinical manifestations of the recurrent oral ulcer mainly comprise skin and mucosal ulcer impairment. Traditional Chinese medicines comprising Souliea vaginata, nervos brake herb, Meadowrue Root and Rhizome, root of Cynoglossumfurcatum Wall., Entireleaf Neoalsomitra, Vietnamese Sophora Root, Natural Indigo, Pyrethrum tatsienense, Euphorbia humifusa Willd, Bigleaf Beautyberry Leaf, catechu, red halloysite, Rhizoma Panacis Majoris, selenitum and all-grass of Climbing Hedyotis are processed in the preparation department of the hospital in which the inventor of the invention works to prepare a decoction. The result of clinic tests shows that the total effective rate of the composition is 96.9% and is obviously higher than that of a contrast group, so the curative effects of the composition are good.

The present invention provides an Chinese traditional medicines oral liquid preparation for treating recurrent oral ulcer and halitosis which is prepared from 15 Chinese traditional medicines including dandelion, jidi tree, figwort, herba hyperici japonici etc. The medicine is main used for treating stomatology obstinate mucosa ulcer, oral cavity catarrh, gingivitis, salivoadenitis, oral cavity obstinate halitosis and oral cavity soft tissue cyst etc. The medicine has the merits of easy preparing medicine, easy administration, simple machining technology, precise target, strong guiding force, fast effects, better curative effects, non-toxic side effects, clinical application efficiently and 100% curing rate. The oral liquid has great application value in clinical application, and provides reliable scientific references for discussing and developing new medicine.

Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy / radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

The invention discloses a composition for treating oral mucositis. The composition is prepared from ropivacaine mesylate and an aluminum hydroxide and magnesium hydroxide suspension in a dose ratio of 0.5-5mg to 1ml. The invention further discloses a method for preparing the composition for treating oral mucositis. The method comprises the following steps: 1, preparing the suspension from hydroxyethyl cellulose, hydroxy propyl cellulose, simethicone, aluminum hydroxide and magnesium hydroxide; 2, adding sorbitol, mannitol and butyl p-hydroxybenzoate to regulate the pH value to obtain the aluminum hydroxide and magnesium hydroxide suspension; and 3, adding ropivacaine mesylate into the aluminum hydroxide and magnesium hydroxide suspension, and uniformly stirring to obtain the suspension for treating oral mucositis. The invention further discloses an application package for the composition for treating oral mucositis. The composition for treating oral mucositis has the advantages of relieving pain and diminishing inflammation, repairing the mucosa ulcer face and the like, and is convenient to use.

The invention relates to application of ozonized oil in small surgical incisions or other wound such as mucosal ulcer, diabetic feet, cervical erosion, anal fissure, anus fistula, soft tissue injury,fall damage wound surface, recurrent wound, abscess, acne, arthritis, joint degeneration, cystitis, furunculosis, neurological disorder osteomyelitis, gangrene, ulcus cruris, synovitis, gout, sinusitis, spondylitis, scapulohumeral periarthritis, lumbocrural pain, periostitis and stomatitis. Through the modes of oral administration, intraperitoneal injection, clyster, gavage, intravenous injection,subcutaneous injection, intramuscular injection, external application, drop and suppository, the diseases can be effectively prevented and treated.

A Chinese medicine in the form of plaster for treating oral mucosa ulcer is composed of a medicinal layer made of the Chinese medicine for treating mucosa ulcer and adhesive and an isolating layer containing water isolating material. Its preparing process is also disclosed.

The invention provides a composition with the effect of improving acute gastric mucosal injury. The composition is composed of 3 parts by weight of costunolide and 0.7-12 parts of dehydrocostus lactone. The composition of the invention can improve gastric mucosal injury, prevent acute gastric mucosal injury, significantly reduce the level of TNF-alpha, NF-kappaB, NO, iNOS and MDA in gastric mucosal injury, significantly increase the level of SOD and PCNA, and promote the healing of mucosal ulcer. When the proportion of components of the compositions is 3:1, the levels of proinflammatory factors, NO, iNOS, oxidative stress factors and PCNA are significantly affected (p is less than 0.001). The composition has a good application prospect.

The present invention relates to a use of 3,6-anhydro-L-galactose for preventing dental caries. More specifically, 3,6-anhydro-L-galactose inhibits the growth of oral microorganisms and exhibits anti-caries activity to inhibit the production of acids caused by the consumption of a carbon source by the oral microorganisms. Thus, 3,6-anhydro-L-galactose can be used in pharmaceuticals, food products, oral hygiene preparations, etc. for preventing, ameliorating or treating oral diseases caused by oral microorganisms, such as dental caries, gingivitis, periodontitis, oral mucosal ulcer, halitosis or xerostomia.

Directed at the problem of secondary mucosal tissue trauma generated to cancer patients after chemoradiotherapy, the invention provides a biopolysaccharide material composition for treatment of oral mucosal ulcer in chemoradiotherapy patients. The composition is characterized by comprising the following components by weight percentage: 1.3-36.1% of a biopolysaccharide material, 0.1-15% of an adhesive, and the balance deionized water. The composition has the functions of inhibiting pathogenic bacteria, promoting wound healing, reducing inflammatory reaction, etc., and provides an effective therapeutic scheme for ulcers of cancer patients undergoing chemoradiotherapy.

The invention provides a nursing lotion with the functions of promoting mucosal injury and inflammatory repair, regulating body fluid secretion, removing odor, protecting skin and the like. The lotioncontains 1-10 parts by weight of tea saponin or an amino acid surfactant or a mixture of the tea saponin and the amino acid surfactant in any proportion, 0.05-2 parts by weight of guaiac wood essential oil, 0.05-5 parts by weight of frankincense and an extract thereof, 0.01-1 part by weight of sodium azulene sulfonate, 0-0.2 part by weight of menthol and 87-98 parts by weight of a base liquid system (consisting of a small amount of alcohol and purified water). The novel nursing lotion prepared by the invention can effectively promote cell tissue healing and regeneration, has a good improvement effect on injured mucosal ulcer, can relieve swelling and pain, expel toxins and promote tissue regeneration, can adjust human body fluid secretion, and can promote functional recovery of the reproductive system of a human body. The mild skin-friendly tea saponin and the amino acid surfactant are adopted, so that the lotion has an anti-allergic effect. The lotion is especially suitable for dailynourishing and cleaning of people with frequent sexual life, and has excellent effects.

The invention discloses ointment for treating dermal chronic ulcers. The ointment is prepared from the following raw materials in parts by weight of 8-13 parts of Chinese gall powder, 0.2-0.8 part ofcentipede powder, 0.1-0.5 part of borneol, 15-20 parts of honey, 200-300 parts of mature vinegar, 1-3 parts of colla corii asini powder and 0.3-0.8 part of ginseng powder. The ointment disclosed by the invention can kill and restrain bacteria, remove rotten meat and promote tissue regeneration; besides, in main components, tannic acid contained in the Chinese gall powder has the effect of precipitating protein, after skin and mucosa ulcers are in contact with the tannic acid, tissue protein is solidified, a layer of membrane surfaces is formed to achieve the convergence effect, and scabbing ofa wound surface is promoted, so that the wound surface is protected, outside stimulation is avoided, pain and body fluid losses are reduced, and bedsores, diabetic feet and the dermal chronic ulcerscaused by scalding, cellulitis and the like can be treated; and in addition, the ointment disclosed by the invention is good in bacterium restraining effects, dressing can be changed once every 5-7 days, the dressing changing interval time is prolonged, and a method of changing dressing once every day is changed.

The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating ulcerative colitis, which is prepared from the following raw material components in parts by mass: Agrimony 10-30g, Burnet 9-15g, Woody Fragrance 6-10g, Coptidis 3-10g, Atractylodes 6-15g, Radix Paeoniae Rubra 6-15g, Jiubiying 9-30g, Fotanmu 9-30g, Leech 1-5g. The efficacy of the Chinese medicinal prescription of the present invention is verified by the UC animal model, and the results suggest that the Chinese medicinal prescription of the present invention can significantly reduce the intestinal mucosal ulcer, inflammation and edema of the UC model rats, and can reduce the intestinal tissue inflammation of the model rats. Cell infiltration, reducing crypt damage, and its effect is equivalent to the positive drug mesalamine.

The invention discloses an application of micro-nano MgH2 compound particles in inhibiting leishmania infection and treating leishmania disease. The micro-nano MgH2 compound particles can be used for preparing a pharmaceutical composition for inhibiting leishmania, or preparing a pharmaceutical composition for treating skin or mucous ulcer caused by leishmania infection or viscera damage caused by leishmania infection. It is found for the first time that the micro-nano MgH2 particles can significantly reduce the number of leishmania in macrophages, inhibit proliferation of the leishmania and have a very good insecticidal inhibition effect. The micro-nano MgH2 particles disclosed by the invention can be used for rapidly and effectively curing skin and / or mucosa ulcer caused by the leishmania and functional damage of visceral organs (mainly liver and spleen organs) caused by the leishmania, are good in biological safety and has a huge clinical application value.

The invention discloses a lindera aggregata compound with an antagonistic effect for inflammatory bowel diseases and an application thereof. The lindera aggregata compound is prepared by mixing lindera aggregata extract with dendrobium officinale polysaccharides, wherein the weight of the lindera aggregata extract is 1%-99% of the weight of the lindera aggregata compound. A preparation method forthe lindera aggregata extract comprises the following steps: adding a lindera aggregata tablet into ethyl alcohol in volume concentration of 50-90%, heating, performing reflux extraction and concentrating, thereby acquiring the lindera aggregata extract. The preparation method for the dendrobium officinale polysaccharides comprises the following steps: adding dendrobium officinale into ethyl alcohol, performing water extraction and performing alcohol precipitation. The compound has the effects of relieving the weight loss of enteritis model rat, obviously relieving colon congestion edema, intestinal wall expansion and mucosal ulcer injury, reducing intestinal index and intestinal weight per unit length, regulating intestinal immunologic derangement, restraining intestinal inflammation medium expression, relieving intestinal inflammation response, relieving histopathological change of colon, maintaining intestinal tract state, and the like, and can be used for preparing a drug for preventing and controlling inflammatory bowel diseases.

The invention discloses a composition for repairing gastric mucosa and improving gastric motility and a preparation method of the composition. The composition comprises the following components in percentage by mass: 12.77-45.45% of gymnadenia conopsea, 18.00-50.00% of goldthread root, 6.12-32.26% of endothelium corneum gigeriae galli, 6.12-32.26% of bergamot and 5.66-22.22% of fennel, wherein the sum of the mass percentage of the above components is 100%. The preparation method comprises the following steps: extracting the raw materials, concentrating, drying, crushing, sterilizing, encapsulating and the like to prepare the composition. The composition is a health-care medicine which is green, natural, safe, non-toxic and reliable in curative effect, and has the effects of removing slough, promoting tissue regeneration, invigorating stomach, helping digestion, dispelling cold and relieving pain. The composition has an exact treatment effect on gastric mucosal lesion and gastropathy caused by insufficient gastric motility by promoting repair and regeneration of gastric mucosal ulcer eroded parts, eliminating inflammation and pain, enhancing gastric motility and digestive function and the like, and can be used for preventing and treating gastropathy.

The invention discloses toothpaste for preventing and treating oral ulcer and a preparation method of the toothpaste. The toothpaste comprises a traditional Chinese medicine active component which is formed by compounding a sanchi flower extract, a bletilla striata extract, a radix ampelopsis extract and a clinopodium chinense extract. The toothpaste for preventing and treating oral ulcer provided by the invention is widely applicable to recurrent aphtha, various stomatitis and mucosa ulcer, and can relieve ulcer pain, maintain oral mucosa health and enable the oral ulcer to heal quickly.

The invention provides traditional Chinese medicine for prevention and treatment of intractable oral mucosal ulcers, which comprises dendrobe, pepper, cinnamon, radix angelicae, radix bupleuri, akebiaquinata, rhizoma anemarrhenae, arisaema cumbile, pseudo-ginseng, mint, borneol, cortex albiziae, radix stephaniae tetrandrae, rhizoma phragmitis, fructus forsythiae, radix ophiopogonis and herba ecliptae. The traditional Chinese medicine has advantages of good anti-inflammatory and analgesic effects and good curative effects in prevention and treatment of intractable oral mucosal ulcers, no toxic or side effects, simple production process and stable quality.

The invention discloses an oral cleaning solution and a preparation method thereof. The oral cleaning solution consists of, by weight, 0.1-0.8 part of decaffeinated tea polyphenols, 0.1-0.3 part of ahoneysuckle flower extract, 0.05-0.2 part of borneol, 0.1-0.3 part of a sweetening agent, 0.01-0.02 part of Vc, 10-20 parts of ethanol and 80-90 parts of deionized water, wherein the caffeine contentof the decaffeinated tea polyphenols is 0.5-1%. The oral cleaning solution has strong killing and inhibition effects on pathogenic bacteria in oral cavities, has the function of protecting oral mucosaand has outstanding advantages of promoting the rapid healing of oral mucosal ulcer and relieving mucosal bleeding.

The application of the invention provides a feed additive. The feed additive comprises N-acyl cysteamine compounds. The N-acyl cysteamine compounds provided by the application of the invention are preferentially selected and obtained by a reaction of cysteamine and acyl chloride. The application further provides a feed. The N-acyl cysteamine compounds are added in the feed of the application, and an acyl group is taken as a protecting group of the cysteamine, so that the N-acyl cysteamine compounds have no irritation, and do not cause gastrointestinal mucosal ulcers, furthermore, the N-acyl cysteamine compounds are slowly decomposed into the cysteamine to take effect under the action of pancreatic lipase, and can be used as animal growth promoters, so that the animal growth can be promoted and the weight gain rate and the feed conversion rate can be improved.

The invention relates to a composition for treating acute gastritis and its application, belonging to the field of biomedicine. The composition is composed of the following raw materials in parts by weight: 20-30% of berberine, 10-30% of evodiamine, 15-30% of evodiamine and 10-30% of dehydroevodiamine. Application of the above composition in the preparation of medicines for treating acute gastritis. The invention has the advantage of significantly reducing the gastric mucosal ulcer index of mice.

The invention relates to a nipped caring device for relieving ulcerous stomatitis of a patient during chemotherapy. The nipped caring device comprises a min pipe body, an infiltration caring component and an atomizing component, wherein the main pipe body consists of a straight barrel part, a reducing part and a horn part which are integrally connected; the main pipe part is internally provided with cross separating boards arranged along the axial direction; the infiltration caring component comprises a liquid guiding cylinder, a liquid storing balloon, an infusion tube and an infiltration connecting head; the atomizing component comprises an atomizer, a liquid feeding pipe and an atomizing connector. The nipped caring device disclosed by the invention has two alternative functions, namely a nebulizer therapy function and an infiltration pain relieving function; the two functions can be quickly switched; the nipped caring device is convenient to use and is suitable for being popularized in hospitals.

The invention provides a care lotion taking full-spectrum CBD oil or pure CBD powder extracted from industrial cannabis sativa as a core functional component. The lotion contains 1-10 parts by weight of a surfactant, 0.05-2 parts by weight of the full-spectrum CBD oil or pure CBD powder, 0.05-10 parts by weight of an auxiliary component and 78-98 parts by weight of a base solution (consisting of a small amount of alcohol and purified water) system. The prepared novel nursing lotion can be made into various preparation forms such as water, gel and gel, can effectively resist inflammation, has a good improvement effect on damaged mucosal ulcer, can relieve swelling and pain, relieve itching, adjust human body fluid secretion and promote functional recovery of a human body reproductive system, and has a good application prospect. The shampoo is especially suitable for daily maintenance and cleaning of people with frequent sexual life.

The invention discloses a traditional Chinese preparation for treating ulcers, and the traditional Chinese preparation is prepared by the following medicinal materials by weight ratio: 10-30g of Chinese gall, 8-20g of Chinese violet, 10-18g of Mongolian dandelion herb, 10-20g of figwort root, 8-15g of golden thread, 10-30g of baical skullcap root, 10-25g of vietnamese sophora root, 20-30g of natural indigo and 6-12g of borneol. The medicament is mainly used for treating oral ulcers, peptic ulcers, ulcerative colitis and other mucosal ulcer diseases, and can rapidly stop pain and astringe the ulcer surfaces, the treatment course is short, the individual differences are avoided and the treatment effects are significant. The medicament is simple in ingredients, belongs to pure traditional Chinese medicine preparations and has no toxic or side effects. The medicament powder can be effectively adsorbed on the ulcer surfaces for directly acting on focuses, the medicament effect is sustained, the adsorption of the medicament on the ulcer surfaces has not been reported in the aspect of traditional Chinese medicine theory, and the formula still belongs to the first time.

The invention provides an application of dehydroevodiamine in preparation of a drug used for treating acute gastritis, and relates to the field of biological medicines. According to the application ofthe dehydroevodiamine in preparation of the drug used for treating the acute gastritis, the dehydroevodiamine can significantly improve the gastric mucosa MDA and SOD levels of mice with the acute gastritis, and the dehydroevodiamine can significantly reduce the gastric mucosal ulcer index of the mice. The drug used for treating the acute gastritis is prepared from the dehydroevodiamine with an effective amount and a pharmaceutically acceptable carrier, wherein the pharmaceutically acceptable carrier is selected from the group consisting of a diluent, a disintegrating agent, an adhesive, a lubricant and a stabilizer. The dehydroevodiamine provided by the invention has the following advantages: 1, the dehydroevodiamine can significantly improve the gastric mucosa MDA and SOD levels of theacute gastritis mice; and 2, the dehydroevodiamine can significantly reduce the gastric mucosa ulcer index of the mice;