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Medicinal composition for treating leukaemia

A composition, leukemia technology, applied in the directions of drug combination, drug delivery, pharmaceutical formulation, etc., can solve problems such as inability to completely relieve symptoms, large rejection of patients, and recurrence of patients' disease, so as to improve the human body's disease resistance and survival time. The effect of lengthening and eliminating disease foci

Inactive Publication Date: 2008-12-31
胡果孙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Second, the patient's rejection reaction is large, resulting in a low success rate
[0011] Third, many patients after transplantation relapsed
Still can't completely alleviate the disease
[0012] Fourth, the cost of transplantation is too high. In my country, the cost of transplant surgery ranges from more than 100,000 yuan to as much as 200,000 to 300,000 yuan. Ordinary patients simply cannot afford it.

Method used

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  • Medicinal composition for treating leukaemia
  • Medicinal composition for treating leukaemia
  • Medicinal composition for treating leukaemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Codonopsis 3000 grams, Atractylodes macrocephala 1000 grams, Yunling 1000 grams, angelica 3000 grams, Chuanxiong 300 grams, white peony root 1000 grams,

[0057] Rehmannia glutinosa 2000g, rhubarb 300g, Shouwu 3000g, Vitex 1000g, realgar 300g, Qingdai 300g,

[0058] 300 grams of peanut shells, 300 grams of roasted licorice, 1,500 grams of medlar, and 3,000 grams of buffalo horn.

[0059] After the above drugs are carefully selected, impurities are removed, dried, sterilized, crushed into 200-mesh fine powder with a pulverizer, and one or several additives such as soybean oil, sesame oil, starch, sucrose, stevioside, citric acid, Sodium bicarbonate, dextrin, etc. are processed into pills, which can be made into ordinary water pills or honeyed pills. Available in sugar or sugar-free form.

Embodiment 2

[0061] Codonopsis 1600 grams, Atractylodes macrocephala 800 grams, Yunling 800 grams, angelica 2000 grams, Chuanxiong 300 grams, white peony root 800 grams,

[0062] Rehmannia glutinosa 1800g, rhubarb 300g, Shouwu 1800g, Vitex 600g, realgar 300g, Qingdai 300g,

[0063] 300 grams of peanut shells, 300 grams of roasted licorice, 1500 grams of medlar, 3000 grams of buffalo horn powder.

[0064] Grind the above drugs into coarse powder, decoct 2-3 times with water, 1-3 hours each time, filter; combine the filtrates, concentrate to a relative density of 1.10-1.40 (55-60°C), add ethanol to the alcohol content reach 50%, stand still for 24 hours; filter, recover ethanol from the filtrate, concentrate to a thick paste with a relative density of 1.35-1.38 (55-60°C), vacuum-dry, grind into fine powder, add appropriate amount of auxiliary materials, mix well, and granulate. Compressed into 1000 tablets, coated with sugar to obtain tablets.

Embodiment 3

[0066] Codonopsis 3300 grams, Atractylodes macrocephala 1500 grams, Yunling 1500 grams, angelica 3300 grams, Chuanxiong 600 grams,

[0067] 1500 grams of white peony, 3300 grams of rehmannia, 600 grams of rhubarb, 3300 grams of Shouwu, 1600 grams of jingzi,

[0068] 800 grams of realgar, 600 grams of Qingdai, 600 grams of peanut shells, 600 grams of roasted licorice, 1500 grams of medlar,

[0069] Buffalo horn 2000 grams.

[0070] The above medicines are dried at 80-105° C. to make the water content ≤ 8%, pulverized, and passed through a No. 1 sieve. According to the material-to-liquid ratio of 1:5-10, water leaching at a temperature of 60-98°C for 3-12 hours, repeated twice, filtering to remove slag, taking the supernatant, and combining the filtrates. The filtrate is sucked into a vacuum concentration tank and concentrated to 1 / 2 to 3 / 4 of the weight of the material under a vacuum of 0.04 to 0.08 MPa. The concentrated material is spray-dried, and the spray drying controls...

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Abstract

The invention discloses a medicinal composition for treating leukemia, which comprises 16-33 parts by weight of Codonopsis pilosula, 8-15 parts by weight of Atractylodes macrocephala, 8-15 parts by weight of Yunling, 20-33 parts by weight of angelica, and 3-6 parts by weight of Rhizoma Chuanxiong 8-15 parts by weight of Radix Paeoniae Alba, 18-33 parts by weight of rehmannia glutinosa, 3-6 parts by weight of rhubarb, 18-33 parts by weight of Shouwu, 3-8 parts by weight of realgar, 3-6 parts by weight of Qingdai, 3-6 parts by weight of peanut coat 6 parts by weight, 3-6 parts by weight of roasted licorice, 8-15 parts by weight of medlar, 6-16 parts by weight of Vitex japonica, 0.3-1.5 parts by weight of rhinoceros horn powder or 20-33 parts by weight of buffalo horn. A large number of clinical observations show that it has high efficiency and low toxicity, has selective killing and therapeutic effects on leukemia cells, has no damage to human tissues and organs, and has obvious effects on repairing and strengthening the eight major systems of the human body, especially on repairing hematopoietic tissues. , is an ideal traditional Chinese medicine for the treatment of leukemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for treating leukemia. Background technique [0002] Leukemia, also known as blood cancer, is a complex disease with multiple causes, multiple diseases, and multiple levels. The pathological, medical and pharmacological research and clinical treatment of leukemia are currently one of the frontier research projects in domestic and foreign medicine, Chinese and Western medicine. [0003] Research Status of Western Medicine on Leukemia [0004] The treatment of blood diseases by Western medicine has roughly gone through several stages such as blood transfusion, exchange transfusion, chemotherapy, bone marrow transplantation, and stem cell transplantation. However, due to the diversity of etiology, there are problems such as repeated illness and a large number of complications during the treatment process, decreased individual i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61K9/14A61K9/16A61K9/08A61K9/48A61K9/46A61K9/20A61P35/00A61K35/32A61K33/36
Inventor 胡果孙万建元胡文波
Owner 胡果孙
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