The invention belongs to the technical field of added material manufacturing, and in particular, relates to a honeycomb interlayer structure prepared through an added material manufacturing method inthe aerospace field. The honeycomb interlayer structure is prepared through a metal powder added material manufacturing method, and comprises a first panel, a honeycomb reinforcing rib, a honeycomb cavity, a second panel and a powder removing process hole, wherein the honeycomb reinforcing rib is positioned between the first panel and the second panel; the first panel, the second panel and the honeycomb reinforcing rib are in metallurgic bonding; the honeycomb cavity is formed in the honeycomb reinforcing rib; and the powder removing process hole is formed in the honeycomb reinforcing rib. Asthe first panel, the second panel and the honeycomb reinforcing rib are in metallurgic bonding, the honeycomb interlayer structure has the characteristics of high lightness degree, high impact resistance, excellent vibration resistance, excellent bending resistance, excellent fatigue resistance and high specific strength. As the honeycomb interlayer structure is prepared through the added materialmanufacturing method, the forming size precision is high, and the surface quality is excellent; and a non-assembled surface is once formed through added material manufacturing, so that the subsequentmachining is not needed, the material utilization rate is high, and the production efficiency is high.