33results about How to "Convenient drinking water administration" patented technology

The present invention provides a tilmicosin dry suspension. The invention also provides a method for preparing the dry suspension and uses thereof. According to the tilmicosin dry suspension of the present invention, via reasonable compatibility of excipients, dispersion of tilmicosin in water is significantly improved, so the tilmicosin is enabled to be evenly distributed in the water in a long time, convenient for clinical administration of medicine by drinking water. Meanwhile, the dry suspension has greatly improved the palatability of the tilmicosin, so the dry suspension can be used not only for animal groups with underdeveloped taste such as chickens, but also for other animal groups with sensitive taste such as pigs, thus expanding the scope of application of the product.

The invention discloses florfenicol soluble powder and a preparation method thereof. The soluble powder is composed of a florfenicol polydopamine compound and a substrate diluent. A preparation method of the florfenicol polydopamine compound comprises the following steps that 1, a surface active agent and florfenicol are added to an alkalescent solution and evenly mixed to obtain a mixture A, wherein the surface active agent can be added or not added; 2, dopamine hydrochloride is added to the mixture A, stirring is continuously conducted, a mixture B is obtained, spray drying is conducted, and the florfenicol polydopamine compound is obtained. The preparation method of the florfenicol soluble powder comprises the steps that 1, the substrate diluent and the florfenicol polydopamine compound are weighed through calculation, then the florfenicol polydopamine compound and the substrate diluent are mixed to be uniform, and the florfenicol soluble powder is obtained. The florfenicol soluble powder contains the florfenicol polydopamine compound, solubility of the florfenicol can be effectively improved, and the dissolving-out speed can be increased. The method is simple and easy to carry out, the time needed in preparation is short, and the production energy consumption is small.

The invention relates to the technical field of veterinary medicine preparation, and particularly relates to wettable sulfamonomethoxine (sodium) powder and a preparation method thereof. The wettable sulfamonomethoxine (sodium) powder provided by the invention is added with potassium citrate, a suspending agent and a wetting agent on the basis of effective components of the original medicine; by reasonable medicine proportioning, the invention provides the wettable sulfamonomethoxine (sodium) powder which is easy to disperse evenly in water, convenient to absorb by animals, and small in toxic and side effects. Compared with commercially available compound sulfamonomethoxine (sodium) powder, the wettable sulfamonomethoxine (sodium) powder is convenient to use and good in therapeutic effect. The invention also provides the preparation method of the wettable sulfamonomethoxine (sodium) powder, and the preparation method is simple in technology, low in production cost and suitable to industrialized production.

The invention provides a wettable ivermectin albendazole oxide powder which is prepared from the following raw and auxiliary materials in parts by weight: 2.5-10 parts of albendazole oxide, 0.1-0.8 part of ivermectin, 0.5-3 parts of magnesium stearate, 43.9-74 parts of powdered sugar, 3-11 parts of sodium lauryl sulfate, 0-8 parts of xanthan gum, 0.6-1 part of fresh milk essence, 0.6-1 part of soluble saccharin and 10-30 parts of sodium citrate. The invention also provides a preparation method and application of the wettable ivermectin albendazole oxide powder. According to the invention, the dispersity of ivermectin and albendazole oxide in water is obviously enhanced, so that the ivermectin and albendazole oxide can be uniformly distributed in water for a long time, thereby facilitating administration by drinking water in clinic; the ivermectin albendazole oxide powder with the additional function of feed attraction has the function of feed attraction when being used for pigs and other animals with sensitive gustation; and the invention has the advantages of simple preparation technique and low production cost, and is suitable for industrialized mass production.

The invention provides wettable fenbendazole ivermectin powder which is prepared from the following raw materials and auxiliary materials in parts by weight: 2.5-10 parts of fenbendazole, 0.1-0.8 part of ivermectin, 0.5-3 parts of magnesium stearate, 43.9-74 parts of powdered sugar, 3-11 parts of sodium dodecyl sulfate, 0-8 parts of xanthan gum, 0.6-1 part of fresh milk essence, 0.6-1 part of saccharin sodium and 10-30 parts of sodium citrate. The invention also provides a preparation method and application of the wettable fenbendazole ivermectin powder. The wettable fenbendazole ivermectin powder significantly improves the dispersity of the ivermectin and fenbendazole in water to ensure that the ivermectin and the fenbendazole can be uniformly distributed in the water for a long time to facilitate clinical water drinking and administration; and wettable fenbendazole ivermectin powder has a food calling function, namely that the fenbendazole ivermectin powder has a food calling function when used on faunas with sensitive tastes, such as pigs and the like. The wettable fenbendazole ivermectin powder is simple in preparation process, low in production cost and suitable for industrial large-scale production.

The invention relates to the technical field of veterinary medicine preparation, and particularly relates to wettable sulfamethoxydiazine powder and a preparation method thereof. The wettable sulfamethoxydiazine powder provided by the invention is added with potassium citrate, a suspending agent and a wetting agent on the basis of effective components of the original medicine; by reasonable medicine proportioning, the invention provides the wettable sulfamethoxydiazine powder which is easy to disperse evenly in water and convenient to take with water. Compared with commercially available compound sulfamethoxydiazine powder, the wettable sulfamethoxydiazine powder is good in therapeutic effect, convenient to use and small in toxic and side effects. The invention also provides the preparation method of the wettable sulfamethoxydiazine powder, and the preparation method is simple in technology, low in production cost and suitable to industrialized production.

The invention relates to the technical field of veterinary medicine preparation and particularly relates to wettability andrographis paniculata powder and a preparation method thereof. The wettability andrographis paniculata powder which can easily and uniformly disperse in water and is beneficial to administration with water is prepared by adding a suspending agent and a dispersing agent on the basis of an andrographis paniculata effective component through the reasonable medicine proportioning. The wettability andrographis paniculata powder provided by the invention is convenient to use and has a good treatment effect. The survey tests on the curative effect on animals show that the treatment effect of the wettability andrographis paniculata powder on swine pneumonia is obviously superior to that of tilmicosin premix (P is less than 0.05), and the treatment effect of the wettability andrographis paniculata powder on broiler chicken pullorum disease is obviously superior to that of commercially available andrographis paniculata powder (P is less than 0.05). The invention also provides a preparation method of the wettability andrographis paniculata powder. The preparation method is simple in process, low in production cost and suitable for industrial mass production.

The invention relates to a veterinary medicine composition and a preparation method thereof. An intestinal virus syndrome vaccine oral liquid synergistic agent is mainly prepared by the following raw materials by weight portion: 10 to 20 portions of atractylis ovata, 15 to 25 portions of dangshen, 10 to 20 portions of sweet wormwood herb, 10 to 25 portions of medicine terminalia fruit, 20 to 25 portions of pomegranate bark, 15 to 20 portions of Flos Poprli, 10 to 20 portions of alisma orientale, 2 to 5 portions of snake gall, 10 to 20 portions of ox-gall, 40 to 60 portions of Chinese aloe, 25to 40 portions of crystal sugar, 18 to 25 portions of neomycin, 10 to 16 portions of oxytetracycline hydrochloride and 8 to 10 portions of sulfamethoxazole sodium. The oral liquid synergistic agent can eliminate toxin in blood and toxin invaded from the outside of organisms, has the characteristic of clearing away heat and toxic materials, can kill fungus, mold and bacteria, inhibit and eliminategrowth and propagation of pathogens, and treat the intestinal virus syndrome. Moreover, the oral liquid synergistic agent has the advantages of convenience in drinking and administration, high absorptivity, wide distribution, no medicine residue, no toxic side effect, and wide safe range.

The invention relates to the technical field of veterinary medicine preparation, and particularly relates to wettable sulfamethoxazole trimethoprim powder and a preparation method thereof. The wettable sulfamethoxazole trimethoprim powder provided by the invention is added with potassium citrate, a suspending agent and a wetting agent on the basis of effective components of the original medicine; by reasonable medicine proportioning, the invention provides the wettable sulfamethoxazole trimethoprim powder which is easy to disperse evenly in water and convenient to take with water. Compared with commercially available sulfamethoxazole trimethoprim premix, the wettable sulfamethoxazole trimethoprim powder is good in therapeutic effect, convenient to use and small in toxic and side effects. The invention also provides the preparation method of the wettable sulfamethoxazole trimethoprim powder, and the preparation method is simple in technology, low in production cost and suitable to industrialized production.

The invention discloses a preparation method of a tilmicosin preparation, which comprises the following process steps: taking polyethylene glycol 6000 as a carrier, adding an anionic surfactant with a mass of 1 to 3% of the carrier, and heating in a constant temperature water bath at 60°C Make it all melt, then add the tilmicosin raw material drug while stirring until it is completely melted, the drug-loading ratio by mass is 1:2, then quickly pour it into a pre-cooled stainless steel container, and place it in a -20°C refrigerator in turn Solidify, dry in a drying oven at 35-40°C, and finally grind and pass through an 80-mesh sieve to obtain the finished product. The invention solves the problems of the existing tilmicosin preparations being insoluble in water, bitter in taste and low in bioavailability, and adopts solid dispersion technology to prepare the tilmicosin preparation capable of masking the bitter taste, soluble in water and high in bioavailability , it is convenient for drinking water to administer medicines, and can treat diseases in time, thereby bringing greater convenience and benefits to the breeding industry.

The invention belongs to the field of vegetable drug products and discloses echinacea purpurea (L.) Moench root granules as well as a preparation method and application thereof. The content of chicoric acids in the echinacea purpurea (L.) Moench root granules is 5-25mg / g. The preparation method comprises the following steps: grinding the drug materials, namely echinacea purpurea (L.) Moench roots and sieving the ground echinacea purpurea (L.) Moench roots to obtain echinacea purpurea (L.) Moench root powder; mixing the echinacea purpurea (L.) Moench root powder with an ethanol solution with percentage concentration by weight of 50-80% to soak the echinacea purpurea (L.) Moench root powder, carrying out ultrasonic extraction twice, filtering the extracts and collecting the filtrate and the residues; mixing the residues with an ethanol solution with percentage concentration by weight of 10-30%, carrying out ultrasonic extraction once, filtering the extract, collecting the filtrate and combining the filtrates; recovering ethanol from the filtrate at reduced pressure and concentrating ethanol; spray-drying the concentrated solution to obtain extract powder; mixing the extract powder with an auxiliary material and granulating the mixture; carrying out fluid bed drying, powder sieving and filling, thus obtaining the echinacea purpurea (L.) Moench root granules. The echinacea purpurea (L.) Moench root granules can obviously enhance the immune effects of Newcastle disease vaccines and porcine reproductive and respiratory syndrome vaccines.