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Wettable experimental pullorum evapotranspiration and preparation method thereof

A wet Zhili powder technology, which is applied in the field of wettable Zhili powder and its preparation, can solve the problems of animal drug intake poisoning, time-consuming, labor-intensive, and limited feeding

Inactive Publication Date: 2014-01-22
CHENGDU QIANKUN VETERINARY PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this dosage form can play a therapeutic role in production, there are still some limitations in application
The powder can only be administered by feeding or mixing. Feeding is time-consuming and laborious, and is not suitable for a large number of group animals; mixing is suitable for group animals, but it is difficult to mix the drug and feed evenly during use. , it is easy to cause animal poisoning due to excessive drug intake or too little drug intake without curative effect

Method used

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  • Wettable experimental pullorum evapotranspiration and preparation method thereof
  • Wettable experimental pullorum evapotranspiration and preparation method thereof
  • Wettable experimental pullorum evapotranspiration and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0127] Example 1 Formula screening of wettable Zhili powder of the present invention

[0128] The screening formula is shown in formula 1 to formula 7 in Table 1:

[0129] Table 1 Screening formula of wettable Zhili powder formula of the present invention

[0130]

[0131] Weigh the raw materials in formula 1 to formula 7 in Table 1 respectively, mix the realgar, talc, xanthan gum, fresh milk essence, and sodium saccharin evenly, and grind them into 625-mesh ultrafine powder for later use; take β- Cyclodextrin, add 30kg of water, stir to dissolve and heat to 50°C, slowly add methyl piperonol while stirring, stir at constant temperature for 1 hour, refrigerate for 24 hours, add the fine powder prepared above, mix well, and ventilate and dry at 40°C , sealed and packaged to obtain the wettable Zhili powder prepared from formulas 1 to 7.

[0132] The wettable Zhili powder prepared from formula 1 to formula 7 was evaluated for dispersion quality, sedimentation volume ratio qu...

Embodiment 2

[0149] Example 2 Preparation of wettable Zhili powder of the present invention

[0150] formula:

[0151]

[0152] The above raw materials are weighed, mixed evenly, crushed to 625 mesh ultrafine powder, packed, and wettable Zhili powder of the present invention is obtained.

Embodiment 3

[0153] Example 3 Preparation of wettable Zhili powder of the present invention

[0154] formula:

[0155]

[0156] Weigh the above raw materials, mix realgar, talc, xanthan gum, fresh milk essence, saccharin, and sucralose evenly, and grind them to 625 mesh fine powder for later use; take β-cyclodextrin, add 30kg of water, stir to dissolve and heat to 50°C, slowly add methyl piperonol while stirring, stir at constant temperature for 1 hour, refrigerate for 24 hours, add the fine powder prepared above, mix evenly, dry at 42°C, and seal the package to obtain the wettable Zhili powder of the present invention. .

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PUM

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Abstract

The invention relates to the technical field of veterinary medicine preparation, in particular to wettable experimental pullorum evapotranspiration and a preparation method thereof. A suspending agent is added to the wettable experimental pullorum evapotranspiration based on original effective composition of herbs, and through reasonable medicine matching, the wettable experimental pullorum evapotranspiration is easy to scatter evenly in water, and beneficial to dosing during water drinking. Compared with commercially available experimental pullorum evapotranspiration, the wettable experimental pullorum evapotranspiration is good in therapeutic effect and convenient to use. The preparation method of the wettable experimental pullorum evapotranspiration is simple in technology, low in production cost, and suitable for industrial mass production.

Description

technical field [0001] The invention relates to the technical field of veterinary drug preparation, in particular to a wettable Zhili powder and a preparation method thereof. Background technique [0002] Zhili San is a traditional Chinese medicine preparation recorded in the Veterinary Pharmacopoeia of the People's Republic of China. It is composed of realgar, Huoxiang and talc. In the prescription, realgar is used to dry dampness and detoxify, which is the monarch drug; Huoxiang aromatizes dampness, harmonizes the middle to stop vomiting, disperses external evils, promotes qi and transforms stagnation, and is the minister drug; [0003] Realgar is one of the sulfide minerals of arsenic, containing about 70.1% As. Modern pharmacological studies have shown that realgar has broad-spectrum antibacterial and antiviral effects. Plasmodium murine and Schistosoma japonicum can inhibit and kill, and can also enhance the phagocytosis of RES and improve the body's non-specific immu...

Claims

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Application Information

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IPC IPC(8): A61K36/532A61K36/53A61K33/36A61K47/48A61K47/38A61K9/14A61P1/12A61K33/12
Inventor 丁晓刚
Owner CHENGDU QIANKUN VETERINARY PHARMA
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