The invention relates to a multifunctional auxiliary material composition for a oral fast-release tablet, and a preparation method of the oral fast-release tablet, and belongs to the field of
medicine preparations. The auxiliary material composition comprises, by
mass, 0.1-80% of a
sugar alcohol filler, 0-20% of a powdered
sugar filler, 0-20% of other fillers, 5-20% of a disintegrating agent, 0.1-5% of a
lubricant, 0.1-5% of a flavoring, and 0-2% of a flow aid. The multifunctional auxiliary material has good fluidity and
compressibility, can be applied to a
powder direct-tabletting technology, is suitable for preparing various oral fast-release tablets of medicines and health foods through
granulation and tabletting, and is especially suitable for oral disintegrating tablets, chewing tablets, buccal tablets, sublingual tablets, dispersing tablets and other dosage forms, and the auxiliary material and the preparation method are suitable for industrial large-scale production, and provide very good auxiliary material and technology choices for the preparation of oral fast-release tablets having excellent
mouthfeel, stable quality and stable process.