The invention discloses a practical simulation test system for the full-station system of a digital intelligent transformer substation, and in particular relates to a digital transformer station control system with the core based on IEC61850 standard, comprising three layers, i.e., a course layer, an interlayer and a transformer station layer, wherein protective equipment, measurement and control equipment, metering equipment and other equipment are located in the spacing layer, information can be interchanged between the spacing layer and the course layer through sampling values mapped by specified communication services and object-oriented transformer station events, information interchange is completed according to service of IEC61850 standard, the digital transformer station control system with the core based on IEC61850 standard is connected with a compatible practical stimulation test system, and the practical simulation test system takes a stimulation test mainframe as a basis, takes a multipath digital analogue simulation comprehensive test device as the core, and comprises digital record and stimulation correction equipment, network analysis equipment, a wireless transceiver, a small semaphore test unit and a network switch which are on the basis of IEC61850 communication protocol.