The embodiment of the invention discloses a composition with the function of relieving visual fatigue. The composition is composed of, by weight, 10,000-20,000 parts of blueberries, 500-1,000 parts ofChinese wolfberry fruits, 1-1.8 parts of
nicotinamide and 1-1.8 parts of
xanthophyll. The composition can be used for preparing health-care foods or
medicine for relieving visual fatigue, under the synergistic effect of the blueberries, the Chinese wolfberry fruits,
nicotinamide and
xanthophyll, the SOD and GSH-Px activity of
retina cells can be effectively improved, the content of total proteinsof the
retina cells can be effectively increased, the MDA content is remarkably decreased, the completeness of all
layers of cells of the
retina can be further protected, damaged cells are improved,the thickness of the
outer nuclear layer of the retina is increased, and therefore a good effect of relieving visual fatigue is realized. In addition, the composition is free of toxic and side effectsand high in safety.