312 results about "Intra stent" patented technology

Stent systems and methods for expanding and deploying stents in hard tissue such as bone, more particularly within a vertebral body. One exemplary method includes using a stent body that is coupled to a high speed rotational motor with the stent expandable and detachable from an introducer working end. In one embodiment, the stent is a deformable metal body with zig-zag type struts in an expanded configuration that carries diamond cutting particles bonded to the strut surfaces. The “spin” stent is rotated at high rpm's to remove cancellous bone from the deployment site together with irrigation and aspiration at the end of the probe that carries the stent. The stent may be expanded asymmetrically, such as with first and second balloons or by using an interior restraint, to apply vertical distraction forces to move apart the cortical endplates and support the vertebra in the distracted condition. The cancellous bone about the expanded stent as well as the interior of the stent can be filled with a bone cement, allograft or other bone graft material. In one method of use, the spin stent is designed and adapted for (i) treating a vertebral compression fracture (VCF) or for (ii) reinforcing an osteoporotic vertebral body.

This invention relates to the design and function of a device which allows for retrieval of a previously implanted valve prosthesis from a beating heart without extracorporeal circulation using a transcatheter retrieval system, including a guide component to facilitate the compression of the valve and retraction into a retrieval catheter, as well as an improved prosthetic transcatheter heart valve having one or more of: a series of radially extending tines having a loop terminus to improve sealing a deployed prosthetic mitral valve against hemodynamic leaking, a pre-compressible stent-in-stent design, or an articulating cuff attached to a covered stent-valve and a commissural sealing skirt structure attached to the underside of the articulating cuff.

A system for treating a body lumen is disclosed. The system comprises an outer stent and an inner stent disposed within the lumen of the outer stent. At least one end of the inner stent extends outside of the lumen of the outer stent, so that the end of the inner stent contacts and conforms to the body lumen wall that is adjacent the end of the outer stent. A coating can be disposed on a surface, preferably the outer surface, of the inner stent. The coating contains a therapeutic substance that may be released into the body lumen wall to help in preventing restenosis. Also disclosed is a stent having a balloon-expandable portion connected to a self-expanding portion. Methods for deploying the system and the stent are also disclosed.

A second stent having a wall thickness of 0.002 inches or less or a second stent having a tubular surface with openings therethrough where the ratio of the area of the surface to the area of the openings is at least 3:10 may be implanted in a first stent which has been previously implanted in a bodily vessel.

A stent graft delivery system includes an internal lead screw assembly within a track of a handle. The internal lead screw assembly is moveable along a major axis of the handle by rotation of a lead screw nut that extends about the handle and is threadably engaged with the threaded portion of the internal lead screw assembly. The lead screw nut is also slidable along the handle while engaged with the internal lead screw assembly. A stent graft system includes a proximal stent adjacent to a bare stent of angled struts joined by proximal and distal apices, wherein the proximal stent is nested within the bare stent.

A stent delivery system deploys a stent having an inner periphery that defines an interior space extending lengthwise along at least a part of the stent and comprising at least one segment having relatively low column strength. The stent delivery system comprises a stabilizer which is disposed within the stent interior space and has a surface element adapted to engage the stent inner periphery in a region containing the low-column-strength segment. The surface element may comprise a sleeve or a coating having a high friction surface adapted to transmit adequate shear force to the stent to move the stent relative to the outer sheath upon deployment. Alternatively, or in addition, the surface element can include at least one radial protuberance. The protuberances may comprise rings of various cross-sections, axial lengths, or space sizes therebetween, or may be in the form of discrete barbs, bumps, or inflatable knobs arranged in a ringed configuration or helical pattern about the stabilizer. The stabilizer may also comprise an inner core and a heat-moldable compression sleeve surrounding the inner core, the heat-moldable compression sleeve having an outer surface comprising a plurality of protuberances defined by a thermal imprint of the stent inner periphery on the compression sleeve outer surface. A method for delivering a stent using a stent delivery system as described herein is also disclosed, as is a method for loading a stent and stabilizer having a heat-moldable compression sleeve into a stent delivery system.

The specification discloses a cardiovascular ostial stents, a ostial stent balloon, and methods for their use. The stent includes two portions having different degrees of expandability. The distal portion has a normal degree of expandability to support a vessel. The proximal portion has a higher degree of expandability so that it can be formed into a flange-like structure. The balloon is designed to deploy the new stent in a single operation. The balloon includes first and proximal portions having different diameters corresponding to the first and proximal portions of the stent. The distal portion is of normal diameter to deploy the distal portion of the stent in the vessel. The proximal portion is of greater diameter to form the proximal portion of the stent into the flange-like structure. The method involves deploying a conventional stent through one branch of the bifurcation, and then deploying one of the novel stent through a wall of the first stent and into the other branch. The flange-like structure on the novel stent secures the novel stent within the conventional stent. Finally, a one-piece Y-shaped stent is provided for placement in a bifurcated artery.

Assemblies are provided comprising a stent and a sensor positioned on and / or in the stent. Within certain aspects the sensors are wireless sensors, and include for example one or more fluid pressure sensors, contact sensors, position sensors, accelerometers, pulse pressure sensors, blood volume sensors, blood flow sensors, blood chemistry sensors, blood metabolic sensors, mechanical stress sensors and / or temperature sensors. Within certain aspects these stents may be utilized to assist in stent placement, monitor stent function, identify complications of stent treatment, monitor physiologic parameters and / or medically image a body passageway, e.g., a vascular lumen.

The method of complicated tubular netted tissue engineering rack forming technology based on core dissolving technique belongs to the field of tissue engineering rack manufacturing technology. The technological process includes first designing 3D model of rack and rack core; making rack core with water soluble material without biotoxicity through fast laminated formation; compounding solution of biocompatible material with proper amount of pore creating agent and coating the solution onto the rack core; air drying, soaking in distilled water to dissolve out rack core and pore creating agent, taking out and volatilizing water and coating different forming material with or without pore creating agent successively to form the tubular netted rack with complicated spatial structure, different material gradient and different pore gradient.

A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand alone secondary scaffold implant or unit for treatment of tissue defects.

A sheath assembly is provided for protecting a stent mounted on a catheter. An inner tubular member is positioned over the stent without longitudinal movement of the inner tubular member along the stent surface thereby eliminating the possibility of scraping or scratching a drug coating or polymer coating on the stent surface or balloon surface. An outer tubular member slides over the inner tubular member to firmly compress it onto the stent for further protection. In use, the outer tubular member is removed from over the inner tubular member so that the two half-cylindrical portions of the inner tubular member can fall away from the stent without longitudinal movement along the stent surface.

Methods and assemblies for dilating and / or delivering a stent into a body cavity or vessel is described. The assembly is particularly suited for the dilation, delivery and fixation of a stent in a body cavity, such as in a stricture in the esophagus, and includes a guidewire, an endoscope having a dilator cap affixed to its distal end, a stent, and a flexible stent delivery device. The dilator cap can be customized to various sizes, depending upon the interior diameter of the stricture to be dilated, and can be interchanged with the other dilator caps on the distal end of the endoscope. The endoscope-dilator assembly can be slid distally down the guidewire to the stricture to be dilated, and the stent can then be delivered distally along the guidewire using a delivery device. The stent delivery device and the endoscope-dilator assembly can be retracted proximally along the guidewire through the interior of the stent, leaving the stent in place in the stricture.

The invention relates to a supporting frame capable of being taken out. In the invention, a sandwich structure that a support is arranged between an inner membrane and an outer membrane is adopted; the connection part of the inner membrane and the outer membrane is opposite to a mesh of the supporting frame; and the supporting frame can freely wriggle in the space formed by the disconnection part of the inner membrane and the outer membrane, therefore, the supporting frame capable of being taken out, provided by the invention, has particularly good flexibility; a full covering membrane structure is adopted to ensure that granulation tissues cannot grow into the supporting frame; and a detachable design is adopted to ensure that the supporting frame can be conveniently taken out. The supporting frame capable of being taken out can be used for inducing and promoting the growth of a neonatal cavity tube, the covering and the epithelization of a mucous membrane, can be conveniently taken out and detached under the direct vision of an endoscopy after the mucous membrane of the neonatal cavity tube is epithelized and the organization is stable, and can be used for a temporary support under the situations of esophagus rebuilding and injury repairing, trachea rebuilding and injury repairing, urethra rebuilding and injury repairing, esophagus-esophagus anastomosing, intestine-intestine anastomosing, nasal cavity rebuilding and injury repairing, external auditory canal rebuilding and injury repairing and the like.

The invention relates to a thrombus taking device. The thrombus taking device comprises a thrombus taking support, a thrombus breaking support and a conveying assembly, wherein the thrombus taking support and the thrombus breaking support are of support structures capable of contracting and expanding; the far end of the conveying assembly is connected with the thrombus taking support and the thrombus breaking support and used for containing the thrombus taking support and the thrombus breaking support which are in a contracting state; and the conveying assembly can release the thrombus taking support and the thrombus breaking support to an expanding state and can drive the thrombus breaking support to move in the internal space of the thrombus taking support in the expanding state in the axial direction of the thrombus taking support. According to the thrombus taking device, the thrombus taking support is matched with the thrombus breaking support, when the thrombus taking support contains thrombus in blood vessels in the thrombus taking support, the conveying assembly controls the thrombus breaking support to stretch into the internal space of the thrombus taking support, and the thrombus breaking support can move in the axial direction relative to the thrombus taking support to cut the thrombus; and therefore, the thrombus in the thrombus taking support is continuously cut and broken; the intractable, large and hard thrombus can be easily broken, and the thrombus taking effect is improved.

The invention discloses a method for preparing a medicine graded sustained-release bone repair body. The method comprises the following steps of: reconstructing a natural cancellous bone micro-computed tomography (micro-CT) scanned image to obtain a three-dimensional model by using Mimics software, and taking positions with uniform pore distribution as stent inner layer and outer layer matrix models through Boolean operation; designing inner layer and outer layer negative models of which the shapes are matched with those of the matrix models by using Magics software, and preparing through fused deposition modeling; and preparing slurry mixed with different medicines, grouting inner layer and outer layer stent matrixes, preparing a stent by a freeze drying process, and thus obtaining a finished bone repair body product. The bone repair body prepared by the method can meet the requirement of a stent material on structural strength and can be loaded with various medicines, the controlled release of the medicines is realized, a sustained-release effect is achieved, and bone repair is well induced and promoted.

The invention discloses a customized alimentary canal support and a moulding method and an application method thereof. The moulding method comprises the steps of building a three-dimensional model of an alimentary canal structure of an individual object, and the alimentary canal structure comprises an alimentary canal stenosis or an obstruction part; performing data analysis and structure adjusting to the three-dimensional model; designing a virtual support by using a software; manufacturing a die corresponding to the inner contour of the support; and braiding a customized alimentary canal support on the die. The application method comprises the steps of delivering the customized support that has 4-6 different signs to a position to be planted. The support is successfully installed when the signs arrive at the designed installation position and the rotation angle under the monitor of an X-ray flat detector. In the complex alimentary canal obstruction areas like turnovers of stomach-duodenum and intestine-intestine, a traditional support fails easily, and the support provided by the invention can be used for a best treatment effect because of having the advantages like non-symmetry, high dissect precision, low internal stress, and difficult rotation shedding.

The invention relates to an intravascular stent and a preparation method and application thereof. The intravascular stent comprises a positioning section and a supporting section, the positioning section comprises a plurality of first repeat single parts, the supporting section comprises at least two supporting units and at least one connection unit, each supporting unit comprises a plurality of second repeat single parts, the first repeat single parts are not as many as the second repeat single parts, and a plane formed by the front ends of the first repeat single parts are perpendicular to the axis of the intravascular stent. The intravascular stent is especially applicable to iliac veins, effective in iliac vein supporting, less in harms to vein walls and capable of effectively avoiding formation of secondary thrombi in the implanted intravascular stent. In addition, the intravascular stent is capable of well positioning in the iliac veins, release accuracy is improved, and convenience in operation is achieved. Furthermore, the intravascular stent is simple in structure, convenient to produce and low in cost, thereby having important practical significances and promising clinical application prospect.

The invention relates to the field of medical materials and devices thereof, in particular to an implantable metal material degradable in vivo and a vascular stent product. A multi-element zinc alloy is composed of, by mass, 0-5% of Li, 0-1.5% of Ti, 0-1.5% of Mg and the balance of Zn. The vascular stent product made of the zinc-based alloy is of a pipe-network structure. The surface of the stent product is provided with a degradable polymer coating which is coated uniformly. Except for the degradable polymer coating, a medicine coating which is coated uniformly is arranged only on one side of the outer wall of a stent. The zinc-based alloy is excellent in mechanical performance, high in corrosion controllability and remarkable in compatibility. In addition, the vascular stent product is reasonable in structure, excellent in supporting force and flexibility; due to special surface arrangement, endothelialization of the stent is facilitated, and inflammatory reaction is reduced; the medicine coating can realize targeted administration.

The invention discloses an artificial heart valve prosthesis and an artificial heart valve stent. The artificial heart valve stent comprises an outer-layer bracket and an inner-layer bracket, whereinthe inner-layer bracket is fixedly connected with the outer-layer bracket, the outer-layer bracket is provided with an outer-layer inflow channel structure and an outer-layer outflow channel structure, the outer-layer inflow channel structure and the outer-layer outflow channel structure are axially connected, the inner-layer bracket is provided with an inner-layer inflow channel structure and aninner-layer outflow channel structure and is located on the inner side of the outer-layer bracket in the radial direction, the inner-layer inflow channel structure and the inner-layer outflow channelstructure are connected in the axial direction, and an anchoring structure is arranged on the outer side of the inner-layer bracket. According to the artificial heart valve prosthesis and the artificial heart valve stent, the inner-layer bracket bears the artificial valve leaflet, and is high in rigidity and small in diameter, so that the area of the artificial valve leaflet can be reduced, the height required by the opening and closing movement of the valve leaflet is reduced, and the service life of the valve leaflet is prolonged; the outer-layer bracket is weak in relative rigidity, large in diameter and capable of preventing perivalvular leakage; and the anchoring structure is connected with the inner-layer bracket, and the anchoring force for preventing the prosthetic valve from moving is mainly borne by the inner-layer bracket with high rigidity, so that the service life of the stent is prolonged.

The invention provides a thrombectomy instrument and a thrombectomy device, and relates to the technical field of medical instruments. The thrombectomy instrument comprises a far-end fixing end, a first near-end fixing end, a second near-end fixing end and a thrombus extraction bracket; the thrombus extraction bracket includes an inner bracket body and an outer bracket body which are connected at the far-end fixing end; the near end of the outer bracket body is connected with the first near-end fixing end, the near end of the inner bracket body is connected with the fixing end of the second near-end fixing end, and the second near-end fixing end is connected with the first near-end fixing end in a sliding mode so that the inner bracket can move relative to the outer bracket body; the thrombectomy device includes a pre-installation sheath, a delivery catheter, an operation controlling rod and the thrombectomy instrument; the operation controlling rod and the thrombectomy instrument are connected, and the installed thrombectomy instrument and the operation controlling rod enter the delivery catheter through the pre-installation sheath, sent to the position of thrombus through the delivery catheter and then released. The problems that an existing thrombectomy instrument can not hold the thrombus in the thrombus extraction process and the thrombus can not be extracted and the thrombus is easy to fall off to cause secondary embolisms when the thrombectomy device is used for thrombus extraction are alleviated.

The invention discloses an intrusive type heart valve prosthesis and a preparation method thereof, and belongs to the technical field of intrusive type medical apparatuses. The intrusive type heart valve prosthesis comprises an elastic bracket, a covering film and at least two valves, wherein the elastic bracket can extend and retract along the radial direction, the covering film is sewed onto the inner wall or the outer wall of the bracket, the valves are arranged in a cavity of the bracket, the lower edge of each valve is sewed onto the covering film, the adjacent sides of the two adjacent valves are mutually spliced, and the side edges of the valves are sewed onto the bracket. The intrusive type heart valve prosthesis has the advantages that the function of natural valves can be well replaced; by adopting the elastic bracket, the valve structure can be conveniently loaded into a conveying device, and can also be conveniently released to the target position to be tightly combined with the surrounding tissues of the target position; the bracket is coated by the covering film, so the surrounding leakage of the valves is effectively prevented; the bionic degree of the sewing structure of the valve and the covering film is high, the natural valves can be well simulated, and the function of the natural valves is replaced; the structure is stable and firm, the durability and firmness are realized, the elastic extending and retracting requirements in the loading and release processes can be met, and the damage is avoided.

The present application relates to a transcatheter valve replacement system. The system includes a valve replacement prosthesis, a delivery catheter, a control handle and an anchoring device; the valve replacement prosthesis includes a valve stent, an artificial valve leaflet and an adaptive covered stent, the artificial valve leaflet is arranged in the valve stent, the adaptive covered stent is connected to the outer periphery of the valve stent, the valve replacement prosthesis is provided with an anchored unit, and the anchored unit is fixed to heart tissue by the anchoring device; and theanchoring device is arranged in the delivery catheter, the anchoring device includes an anchoring needle, an anchoring needle catheter, an anchoring needle push rod, and a controllable guiding device,the anchoring needle is pre-installed in the distal end of the anchoring needle catheter, the distal end part of the anchoring needle catheter has a flexible structure, one end of the controllable guiding device is detachably connected to the anchored unit, and the controllable guiding device can control the distal end part of the anchoring needle catheter to form a fixed bend angle in the radialdirection and make the distal end of the anchoring needle catheter adhered to the anchored unit.

A pipe stent with a double-layered structure comprises an inner layer and an outer layer. Components of the inner layer include polylactic acid and barium sulfate, the weight ratio of the polylactic acid to the barium sulfate is 1-100:1, components of the outer layer include one or more than one of chitosan, hyaluronic acid and collagen, the thickness of the inner layer ranges from 0.1mm to 2mm, and the thickness of the outer layer ranges from 0.01mm to 1mm. The multilayered pipe stent is a degradable pipe stent, the inner layer is a substrate layer and consists of degradable high polymers, the outer layer consists of one or more than one natural high polymers and has the function of antibiosis repair, and stimulation to a pipe due to the stent is relieved. The stent is non-toxic, can be absorbed completely, and is excellent in treatment effect after being tested and verified in an animal experiment. In addition, the method is simple in formula and feasible in preparation process, and has the advantages of low temperature, vacuum, energy consumption and pollution, and the like.

The present invention provides an aortic arch intraoperative stent, wherein the aortic arch intraoperative stent comprising a main body (17) and one to three branches (5, 6, 7), The aortic arch intraoperative stent connects several circular waveform rings together via a cover membrane (25) to form the main body (17) and the branches (5, 6, 7), wherein each circular waveform ring comprises a circular elastic wire formed through head-to-tail connection. In addition, the present invention also provides a manufacturing method for the aortic arch intraoperative stent, comprising the following steps of: providing a cover membrane mandrel (40); making an inner membrane; assembling circular waveform rings; making an outer membrane; suturing a proximal fabric (12); and suturing a distal fabric (13). The aortic arch intraoperative stent can automatically adapt to the vascular structure near the aortic arch of different patients, and the main body (17) in the aortic arch intraoperative stent maintains a sufficient radial support for the branches, thereby ensuring that the branches on the aortic arch intraoperative stent may safely enter branch vessels during surgery, and preventing the branches from slipping out of the corresponding branch vessels during and after surgery at the same time.

A prosthetic heart valve includes stabilization features for anchoring the prosthetic heart valve within a native valve annulus. The prosthetic heart valve includes an expandable stent having an inflow end and an outflow end, and a valve assembly disposed within the stent. One such stabilization feature is a collapsible and an expandable frame formed of compliant wires. The frame has a body including a first end coupled to the stent, a second end, and a lumen extending therethrough for receiving the stent and the valve assembly. When the frame is expanded in the native valve annulus, the compliant wires form an indented region in the frame between the first and second ends of the body and a sub-annulus portion of the frame forms a bulge.

The invention provides a hemodialysis channel thrombectomy device. The device comprises a thrombectomy stent and a conveying assembly; the thrombectomy stent comprises N stent units, and each stent unit is a net-shaped stent which is large in the middle, gradually reduced towards two ends and closed at the two ends. the conveying assembly comprises an outer sheath tube, a pushing tube, an inner tube, a guide head and a suction catheter; a proximal end of the thrombectomy stent is connected with a distal end of the pushing tube, the inner tube penetrates through the pushing tube and the thrombectomy stent, a distal end of the inner tube, a distal end of the thrombectomy stent and a proximal end of the guide head are connected, and the inner tube can axially move relative to the pushing tube to adjust an axial length of the thrombectomy stent; the pushing tube can axially move relative to the outer sheath tube, the outer sheath tube is used for containing the thrombectomy stent in a compressed state, and the thrombectomy stent can be released to an expansion state by controlling the outer sheath tube to axially move towards the near end relative to the pushing tube; the outer sheath tube is arranged in the suction catheter in a penetrating mode and can pull the thrombectomy stent back into the suction catheter when the thrombectomy stent is in an expansion state, and therefore a thrombectomy effect is improved.

An adult stem cells covered internal vascular scaffold is composed of metallic internal vascular scaffold, SIS covering on said scaffold, and adult stem cells planted on SIS. Its preparing process includes such steps as preparing bioactive SIS, separating the endothelial archeocytes from human umbilical blood, planting the archeocytes, and covering on said internal vascular scaffold.

The invention relates to the field of coronary stents, specifically to a method for reducing the incidence of in-stent restenosis and its special stainless steel material. The method of the invention adds a proper amount of copper element (2.0-6.0% by weight) into the common clinical coronary stent material 316L stainless steel, and conducts special heat treatment so as to make the copper separated in a copper-rich phase out of the stainless steel substrate. The stent is enabled to continuously release trace amounts of copper ions in a clinical environment, and the coronary stent is endowed with an anti-restenotic function, thus effectively reducing the incidence of restenosis after stent implantation. With a unique function of reducing the in-stent restenosis phenomenon caused by stent implantation into a coronary artery, the 316L type copper-containing stainless steel of the invention is conducive to solve clinical problems such as high incidence of in-stent restenosis after implantation of existing stainless steel coronary stents, and can be applied in coronary stents and other clinical medicine fields, thus providing a new idea and material basis for development and application of coronary stents.