Pipe stent with double-layered structure and preparation method of pipe stent
A pipeline stent, double-layer structure technology, applied in stents, medical science, surgery, etc., can solve the problem of poor biocompatibility of stents, and achieve the effects of excellent therapeutic effect, simple formula and low energy consumption
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Embodiment 1
[0022] Step 1: Fully mix the mixture of 9g polylactic acid and 0.5g barium sulfate with 100ml solvent methylene chloride to obtain suspension A;
[0023] Step 2: Add the stirred suspension A to 1 ml / cm in the fume hood 2 The ratio of is poured into the glass tank mold Z, and kept ventilated in the fume hood for a certain period of time, until the surface of the film B obtained by the solution volatilization has no specular reflection;
[0024] Step 3: 5g chitosan is dissolved in 100ml 2wt% acetic acid solution, press 1 ml / cm 2 The ratio is poured into the glass tank mold Z with film B at the bottom, and kept ventilated in the fume hood for a certain period of time until the chitosan solution forms a film on film B to obtain composite film C;
[0025] Step 4: Cut the double-layer film C into a strip with a width of 3mm with a blade, and wrap the strip-shaped double-layer film on an iron wire or a small rod with a diameter of 5mm. The adjacent winding strips neither overlap nor...
Embodiment 2
[0029] Step 1: Fully mix the mixture of 8g polylactic acid and 0.5g barium sulfate with 100ml solvent methylene chloride to obtain suspension A;
[0030] Step 2: In the fume hood, mix the stirred suspension A with 0.5 ml / cm 2 The ratio of is poured into the glass tank mold Z, and kept ventilated in the fume hood for a certain period of time, until the surface of the film B obtained by the solution volatilization has no specular reflection;
[0031] Step 3: Dissolve 8g chitosan in 100ml 2wt% acetic acid solution, press 1 ml / cm 2 The ratio is poured into the glass tank mold Z with film B at the bottom, and kept ventilated in the fume hood for a certain period of time until the chitosan solution forms a film on film B to obtain composite film C;
[0032] Step 4: Cut the double-layer film C into a strip with a width of 3mm with a blade, and wrap the strip-shaped double-layer film on an iron wire or a small rod with a diameter of 7mm. The adjacent winding strips neither overlap no...
Embodiment 3
[0036] Step 1: Fully mix the mixture of 9g poly-L-lactic acid (PLLA) and 0.5g barium sulfate with 100ml solvent methylene chloride to obtain suspension A;
[0037] Step 2: Add the stirred suspension A to 1 ml / cm in the fume hood 2 The ratio of is poured into the glass tank mold Z, and kept ventilated in the fume hood for a certain period of time, until the surface of the film B obtained by the solution volatilization has no specular reflection;
[0038] Step 3: 5g chitosan is dissolved in 100ml 2wt% acetic acid solution, press 1 ml / cm 2 The ratio is poured into the glass tank mold Z with film B at the bottom, and kept ventilated in the fume hood for a certain period of time until the chitosan solution forms a film on film B to obtain composite film C;
[0039] Step 4: Cut the double-layer film C into a strip with a width of 3mm with a blade, and wrap the strip-shaped double-layer film on an iron wire or a small rod with a diameter of 8mm. The adjacent winding tapes neither ov...
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