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Customized alimentary canal support and moulding method and application method thereof

A molding method and digestive tract technology, applied in the field of medical devices, can solve the problems of obvious improvement in stent failure rate, inability to fit the digestive tract stent, inability to reduce the internal stress of the stent, etc., to achieve reduced possibility, excellent fit, and reduced sliding the possible effect of

Active Publication Date: 2016-06-08
BEIJING FRIENDSHIP HOSPITAL CAPITAL MEDICAL UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In recent years, various studies have been carried out on the materials, coatings and drug-carrying aspects of gastrointestinal stents. For example, the Chinese patent application number 200510111800.1 of Guo Shengrong et al. discloses gastrointestinal stents containing anticancer drugs, but these studies have not Significant improvement in the failure rate of stents in complex anatomical sites
It cannot make the digestive tract stent better fit the individual anatomical structure, nor can it reduce the internal stress of the stent, and it is easy to fail in complex anatomical areas

Method used

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  • Customized alimentary canal support and moulding method and application method thereof
  • Customized alimentary canal support and moulding method and application method thereof
  • Customized alimentary canal support and moulding method and application method thereof

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Embodiment 1

[0062] A) Establish a three-dimensional model of the digestive tract structure of the individual subject including the stenosis or obstruction of the digestive tract Obtain structural data of the digestive tract through CT

[0063] Patients generally eat a certain amount of contrast medium according to the guidance of clinicians before undergoing CT. It is also possible not to eat contrast agent, only for image enhancement. Use SOMATOMEmotion6-slice configuration (Shanghai Siemens Medical Instrument Co., Ltd.) to obtain the digestive tract structure data of the subject according to the manufacturer's instructions, and save the obtained data in DICOM format. Various MRIs and CTs that can effectively obtain the structure of the digestive tract can be used in the present invention. image 3 A coronal CT reconstruction image of a patient is shown showing a narrowed bowel lumen with heterogeneous thickening of the bowel wall as indicated by white arrows.

[0064] Generation of 3D...

Embodiment 2

[0081] Such as Figure 7 Another example of a patient-based personalized digestive tract scaffold fabricated using the methods described herein is shown. It has a network structure formed by nitinol wires in the way of positive and negative helical crossing, and its central axis has a bend of about 90 degrees. The diameter of the stent varies with the diameter of the digestive tract to be implanted. The range is between 5mm and 40mm. Laser welding is performed at the intersection points to achieve a grid-like stent structure.

Embodiment 3

[0083] Figure 8 Another example of the present invention is shown, which is used at the gastrointestinal transition, which has two transitions, complex structure, and large diameter variation, where the failure rate of conventional stents is high, and the forming method of the present invention is adopted The obtained personalized digestive tract stent fits well with this structure, and can basically maintain a stable position during the peristalsis of the stomach.

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Abstract

The invention discloses a customized alimentary canal support and a moulding method and an application method thereof. The moulding method comprises the steps of building a three-dimensional model of an alimentary canal structure of an individual object, and the alimentary canal structure comprises an alimentary canal stenosis or an obstruction part; performing data analysis and structure adjusting to the three-dimensional model; designing a virtual support by using a software; manufacturing a die corresponding to the inner contour of the support; and braiding a customized alimentary canal support on the die. The application method comprises the steps of delivering the customized support that has 4-6 different signs to a position to be planted. The support is successfully installed when the signs arrive at the designed installation position and the rotation angle under the monitor of an X-ray flat detector. In the complex alimentary canal obstruction areas like turnovers of stomach-duodenum and intestine-intestine, a traditional support fails easily, and the support provided by the invention can be used for a best treatment effect because of having the advantages like non-symmetry, high dissect precision, low internal stress, and difficult rotation shedding.

Description

technical field [0001] The invention relates to the field of medical devices, and in particular, the invention discloses a personalized digestive tract bracket, a forming method and a using method thereof. Background technique [0002] Gastrointestinal stenting has been increasingly used as a nonsurgical palliative treatment for patients with gastrointestinal strictures or gastrointestinal obstruction. Although the traditional gastrointestinal stent with a simple cylindrical structure (as shown in Figure 1) is suitable for most esophagus and relatively flat parts of the intestinal tract, it cannot be used in curved parts such as the stomach-duodenum or intestine-gut junction. , The traditional stent fits poorly with the actual structure of the digestive tract, and it is very easy to cause sliding failure. [0003] Curvatures such as bowel-bowel transitions, such as dextral flexures of the colon (eg, Figure 2c As shown in the schematic diagram), when the traditional digesti...

Claims

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Application Information

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IPC IPC(8): A61F2/91
Inventor 耿建平张澍田廖胜辉石定杨雷曹晓建李鹏王拥军朱圣韬郭水龙
Owner BEIJING FRIENDSHIP HOSPITAL CAPITAL MEDICAL UNIV
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