Medical degradable zinc-based alloy material and vascular stent product thereof

Abstract

The invention relates to the field of medical materials and devices thereof, in particular to an implantable metal material degradable in vivo and a vascular stent product. A multi-element zinc alloy is composed of, by mass, 0-5% of Li, 0-1.5% of Ti, 0-1.5% of Mg and the balance of Zn. The vascular stent product made of the zinc-based alloy is of a pipe-network structure. The surface of the stent product is provided with a degradable polymer coating which is coated uniformly. Except for the degradable polymer coating, a medicine coating which is coated uniformly is arranged only on one side of the outer wall of a stent. The zinc-based alloy is excellent in mechanical performance, high in corrosion controllability and remarkable in compatibility. In addition, the vascular stent product is reasonable in structure, excellent in supporting force and flexibility; due to special surface arrangement, endothelialization of the stent is facilitated, and inflammatory reaction is reduced; the medicine coating can realize targeted administration.

Description

technical field [0001] The invention relates to the field of medical materials and devices thereof, and relates to a biodegradable implantable metal material and a blood vessel stent product thereof. Background technique [0002] Nowadays, with the rapid development of life science and material science, patients are more inclined to hope that the medical devices implanted in the body will only play a temporary or short-term replacement role, and will gradually degrade and be destroyed along with the repair or healing of traumatized tissues or organs. The body absorbs it to minimize the long-term impact of implanted devices on the human body, so degradable biomaterials came into being. Degradable biomaterials are easy to decompose in the living body, and the degradation products participate in metabolism and are finally excreted from the body. widespread concern among healthcare workers and patients. [0003] Degradable medical devices degrade automatically after completing...

AI Technical Summary

Problems solved by technology

For example, magnesium-based degradable metal materials face the problem of poor controllability of corrosion rate, and iron-based degradable metal materials face the problem of too slow corrosion rate, which will cause biological rejection similar to permanent implants in the long run. Zinc-based degradable metals face the problem of insufficient strength and toughness

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