The invention belongs to the technical field of medical apparatuses, and discloses a skin disinfection effect monitoring quick sampling device. The skin disinfection effect monitoring quick sampling device is of a cuboid structure, a portable handle and a control switch are arranged on an upper cover of a cuboid, an automatic door is arranged in the front of the cuboid, and a sampler baseboard isarranged on the bottom face of the cuboid; the sampler baseboard is provided with a receiving pond, a finger groove, a membrane groove, a control box, a chargeable battery and supporting plates; two supporting plates are arranged, a cross rod is in lap joint with the two supporting plates and is provided with a sampling head, and the two supporting plates are provided with ultraviolet lamps respectively. With 'a set time, set pressure and set area' of sampling being a basic principle in combination with a related automated technology, a semi-automated finger skin quick sampler which is convenient, accurate and quick to sample, is designed, and a basis is provided for changing a skin disinfection effect quick detecting method.