The invention provides a negative-pressure transdermal
drug delivery device and aims to solve the problems that a conventional transdermal
drug delivery device injures
skin in the use process and is low in transdermal
drug delivery
curative effect. The technical key points are that a composite drug-loaded dressing containing a drug is loaded into the negative-pressure transdermal
drug delivery device, a meshy elastic member fixed at the edge of the inner wall is arranged in the position, in contact with the
skin, of the negative-pressure transdermal
drug delivery device, and a semi-circular member allowing air to pass is arranged in the internal middle of the negative-pressure transdermal
drug delivery device. After negative pressure is pumped into the negative-pressure transdermal drug delivery device, the surface area of the
skin per unit area is increased, the
skin tissue space is enlarged, and further, the drug transdermal impedance is reduced. Along with increase of the negative pressure, the meshy elastic member and the semi-circular member in the negative-pressure transdermal drug delivery device limits swelling of the skin and tissues, a reversed pushing action force is formed on the skin in negative pressure due to action of resistance, so that the drug can be easily loaded into the skin and enters a
human body through the space-enlarged skin and tissues, and after relief of the negative pressure, the
human body skin tissues recover while the drug remains in the
human body.