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Composition containing toad venom extraction used for pain relieving and anesthesia

A technology of extracts and compositions, which is applied in the field of Chloroform extract preparations of Bufona toad, can solve the problems of short action time, no slow release of drugs, and the inability to use the Bufon extract directly, so as to prolong the action time and prevent the loss of drugs.

Inactive Publication Date: 2006-09-13
SHANGHAI MODERN PHARMA ENG INVESTIGATION CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, toad venom extract cannot be used directly, it does not have the effect of slowly releasing the drug, and keeps the drug in the sore area, the drug is easily lost, and the action time is short

Method used

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  • Composition containing toad venom extraction used for pain relieving and anesthesia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Toad poison toothache drops

[0020] Prescription: bufalin 50mg, polycarboxyethylene mg, ethanol 0.05ml, water 1.0ml.

[0021] Preparation method: add Carbopol to water, adjust the pH to 7 under stirring, add bufalin ethanol, and continue to stir evenly. Pour this agent into a single-use plastic tube or multiple-use device, and squeeze out a drop (equivalent to 0.01ml) on the toothache when using it.

Embodiment 2

[0023] Total extract of toad venom for toothache liquid drops

[0024] Prescription: 0.01mg of total extract of toad venom, 0.01mg of Carbopol, 1.0ml of water.

[0025] Preparation method: adopt the same method as in Example 1 to make drops.

Embodiment 3

[0027] Buad Sue Organic Tablet Extract External Imitation Pain Relief Ointment

[0028] 5 mg of chloroform extract of Bufoni Buena, 2.0 g of a mixture of polyethylene glycol 400 and polyethylene glycol 4000 (4:6, weight ratio), and 1 ml of propylene glycol.

[0029] Add the two kinds of polyethylene glycol into the propylene glycol mixture in various proportions, heat and stir to melt, add the extract of bufo chloroform and continue to stir until dissolved, squeeze and pour it into a disposable ointment or ordinary ointment tube, take an appropriate amount and spread it on the Trauma.

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Abstract

A composition containing the extract of toad venom for anodyne and anesthesia is disclosed, which features that it contains also high-molecular materials, so having slow release function.

Description

technical field [0001] The invention relates to a pharmaceutical preparation for relieving pain, in particular to a chloroform extract preparation of toadstool. Background technique [0002] Pain is a common disease, such as toothache that directly affects people's life and work when it is severe, and cancer pain that affects the patient's quality of life. The current common analgesic drugs have local stimulation, side effects on the central nervous system, etc., and do not have a sustained release function, and the drug has a short action time and needs to be administered multiple times. [0003] Toad venom is the secretion of the auricular glands of Chinese giant toad venom and black orbital toad venom. It is warm in nature, sweet and flat in taste, and has the effects of detoxification, pain relief, resuscitation, and refreshing. Folks have already used toad venom and Liushen pills containing toad venom to treat toothache and sore throat. [0004] Studies have found tha...

Claims

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Application Information

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IPC IPC(8): A61K35/56A61K9/00A61P25/04A61P23/00A61K35/65
Inventor 王浩侯惠民
Owner SHANGHAI MODERN PHARMA ENG INVESTIGATION CENT
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