The invention provides a method for controlling propagation of schistosomiasis in lake regions. The method is characterized in that one or more or all of capsella bursa-pastoris, crescent euphorbia, wild carrot, sedge, Indian mock-strawberry herb, dandelion, clover, tokyo violet herb, artemisia selengensis turcz, field thistle, crescent euphorbia, wormwood, buttercup, wild carrot and the like are grown on the lake regions. The method uses allelopathy of herbaceous plant in lake regions to control schistosoma miracidium to infect oncomelania so as to achieve the aim of controlling the schistosomiasis in lake regions. The invention discloses that certain plants collected from breeding place of the oncomelania, such as the capsella bursa-pastoris, the crescent euphorbia, the wild carrot, the sedge, the Indian mock-strawberry herb, the dandelion, the clover, the tokyo violet herb, the artemisia selengensis turcz, the field thistle, and the like, have obvious rejection on Japanese schistosoma miracidium; and soak solutions of other plants, such as the crescent euphorbia, the wormwood, the buttercup, the wild carrot, and the like, have obvious killing effect on miracidium. The method has the advantages that the aim of protecting human from infection of schistosomiasis can be realized without killing the oncomelania, and has low cost and no environmental pollution.