Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

73 results about "Cough syrups" patented technology

Many codeine cough syrups no longer contain alcohol, so purple drank and similar brews often contain alcohol. Some of the cough syrups may also contain dextromethorphan, or DXM, a cough suppressant that replaced codeine in over-the-counter cold and flu medicines.

Herbal cough formulations and process for the preparation thereof

The present invention relates to herbal composition for the treatment of chronic respiratory disorders such as cold, cough, allergic asthma, seasonal allergic rhinitis, pharyngitis, laryngitis and the like and a process for preparing the same. The composition comprises extracts derived from Ayurvedic plants selected from the following group: The process for preparing the herbal composition of the present invention comprises procuring, cleaning, grading of specified herbal plants as per the standard specification, disintegrating and pulverizing separately to form the coarse powder, then macerating individual powders separately with aqueous solution of preservatives and then extracting, filtering, concentrating and spray drying to make dry extract powder or semisolid soft extract. Further dissolving each of the extracts separately in aqueous solution containing preservatives and then allowing to maturate after mixing. Then adding filtered extracts to the sugar syrup containing preservatives, glycerin and appropriate excipients to obtain a homogenous cough syrup. The herbal composition of the present invention is non alcoholic, non sedating and non-freezing in nature and the process of preparation as described above does not employ pharmaceutically unacceptable organic solvents.
Owner:J B CHEM & PHARMA

Method for purifying esgoside and extracting biological active compound

The invention discloses purification momordica grosvenori glucoside and a method for withdrawing the biological activity material, the method uses the solvent-extraction process to purify momordica grosvenori glucoside, simultaneously withdraws the momordica grosvenori element, and includes the steps that the fluid is prepared, the extract is carried on with moderate nonpolar resolver, the withdrawing is carried on with medium polar organic solvent, and the spraying and the drying are performed. The method of the invention can eliminate the return bitter taste in the momordica grosvenori, the momordica grosvenori sweet material, the extraction of the momordica grosvenori, the momordica grosvenori concentration fruit juice, the momordica grosvenori sweetening agent, and the product, thereby improving momordica grosvenori sweet material taste, purifying momordica grosvenori glucoside, and simultaneously withdrawing the active material, namely, the momordica grosvenori element having anti-microorganism. The momordica grosvenori element has the activeness suppressing microorganism, such as Gram-negative bacteria, Gelanshi masculine fungus and fungus and so on. The anti-microorganism activeness of the momordica grosvenori element extracted with the invention can be used to prepare the anti-microorganism medicine and daily necessities like cough syrup, throat piece, toothpaste, rinses mouth fluid and so on, and the invention can have very great use value and economic value.
Owner:湖北汇特生物医药技术有限公司

Method for determining content of effective ingredient amygdalin in loquat leaf cough syrup

The invention discloses a method for determining content of effective ingredient amygdalin in loquat leaf cough syrup. The method comprises a step of preparation of reference solution, a step of preparation of test solution and a step of high performance liquid chromatographic determination, wherein the condition that content of amygdalin is not less than 1.2mg per 1ml of the loquat leaf cough syrup can be ensured. According to the method, high performance liquid chromatography is used for determining content of the amygdalin controlling quality of loquat leaf cough syrup product, compared with the detection without content determination item in the existing standard, the method has the advantages that the inherent quality of medicine can be directly controlled by determining content of the amygdalin, moreover, in the determination method, the amygdalin is separated well, stability and accuracy both are high and repeatability is excellent, thus, quality of the loquat leaf cough syrup product can be controlled better.
Owner:HUBEI DUANZHENG PHARMA CO LTD

Quality detection method of cough syrup for children

The invention relates to the field of traditional Chinese medicine preparation detection, in particular to a quality detection method of cough syrup for children. The quality detection method comprises the following steps: diluting a sample to be detected with methanol, and filling into a liquid chromatograph for detection, and comparing an obtained chromatogram with a reference fingerprint chromatogram so as to judge the quality of the sample to be detected, wherein the detection conditions of the liquid chromatograph are as follows: octadecylsilane chemically bonded silica is adopted as a filling agent, acetonitrile is adopted as a flow phase A, a 1% acetic acid solution is adopted as a flow phase B, the above components are eluted according to specific programs in a gradient manner, the wavelength is 252-256 nm, the flowing speed is 0.8-0.9 ml / min, the column temperature is 29-31 DEG C, and the number of theoretical plates is no less than 3000 according to the peak of ammonium glycyrrhetate. As multiple influence factors are controlled, the quality detection method of cough syrup for children, which is provided by the invention, is stable, reliable and good in repeatability, achieves the purpose of controlling the quality by virtue of fingerprint chromatogram detection, and meanwhile is significant for ensuring the consistency of quality of each batch of products.
Owner:华润三九(郴州)制药有限公司

Quality control method for infantile cough syrup as Chinese medicine preparation

The invention belongs to the technical field of Chinese patent drug, relating to a quality control method for infantile cough syrup as Chinese medicine preparation, which is prepared from Chinese herbal medicines as raw materials, comprising the following steps: with the reference substances of figwort, lilyturf root and Sarsasapogenin, distinguishing whether the prescription of the infantile cough syrup contains the compounds of figwort, lilyturf root and Sarsasapogenin with thin layer chromatography; and with the reference substance of mono-ammonium glycyrrhizinate, detecting the content of glycyrrhizic acid in the prescription of the infantile cough syrup with high performance liquid chromatography; therefore, the quality standard is relatively perfect, and the quality control of the medicine is improved due to the amended quality standard.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Method for controlling quality of Xingsu cough syrup

The invention provides a method for controlling the quality of Xingsu cough syrup. The method mainly comprises part or all of identification and content determination items, wherein the identification comprises thin-layer chromatography identification of perilla leaves, balloon flower, ephedra, thunberg fritillary bulb and baikal skullcap root; and the content determination means to determine the content of the main active ingredient amygdalin of bitter almonds in a preparation by adopting a high-performance liquid chromatography, and method validation is carried out, so that a reliable and accurate quality control method with strong specificity is established. By adopting the method, the quality control standard of the Xingsu cough syrup is improved, the quality of a product can be effectively controlled, and then the clinical curative effect of the product is definitely ensured.
Owner:蚌埠市第三人民医院

Infantile cough syrup and preparation method thereof

The invention discloses infantile cough syrup and a preparation method thereof. The infantile cough syrup comprises the following raw materials: Chinese ephedra, licorice, radix isatidis, Rhizoma Menispermi, Semen armeniacae amarum, gypsum, radix scutellariae, sucrose, honey, and sodium benzoate. The preparation method includes extracting Chinese ephedra; decocting raw materials for the first time; decocting raw materials for the second time; preparing simple syrup; mixing; filtering, and testing; filling; and sealing, packaging, and warehousing. According to the invention, syrup is prepared from extracts of Chinese medicinal materials by use of traditional Chinese medicine theory to treat infantile cough with quick action and distinct therapeutic effect. The infantile cough syrup has effects of dispelling phlegm, relieving cough, reducing fever, promoting the dispersing function of the lung, relieving asthma, and relieving sore-throat, and is used for treating fever with chills, cough, yellow sputum, shortness of breath, dry mouth, hoarse voice, swelling and pain in throat in infants due to affection by exopathogen. The infantile cough syrup disclosed by the invention has reasonable formula, simple preparation method, no adverse side effects, good safety and reliability, and convenience in administration; and infants do not resist, so that the cough syrup can be easily administrated by infants.
Owner:蔡卓慧

Cough syrup and preparation method thereof

The invention relates to cough syrup and a preparation method thereof, belonging to the technical field of Chinese herbal medicines. Bulbus fritillariae cirrhosae and loquat leaf having efficacies of clearing heat and freeing lung, and preventing phlegm from forming and stopping coughing, ephedra and apricot kernels with efficacies of ventilating lung and arresting cough, rhizoma anemarrhenae and radix stemonae with efficacies of moistening lung for arresting cough, pericarpium citri reticulatae, poria cocos and rhizoma pinelliae with efficacies of tonifying spleen, regulating qi-flowing for eliminating phlegm, and raw liquorice and platycodon grandiflorum with efficacies of relieving sore-throat, preventing phlegm from forming and stopping coughing are adopted, wherein liquorice plays the role of coordinating the properties of the other medicines. The components act together to achieve the efficacies of clearing heat and freeing lung, and preventing phlegm from forming and stopping coughing. The cough syrup is suitable for treating symptoms such as cough yellow phlegm or unsmooth cough up phlegm, senses of suppression and swelling pain in the chest, internal injury of viscera, and the like which are caused by wind-heat affecting lung and phlegm-heat internal blockage; the cough syrup is small in side effect and definite in curative effect, and solves the problems that the existing western medicine only can treat symptoms but can not treat root causes, although can improve the cough symptoms caused by upper respiratory infection, bronchitis and acute laryngitis within the short period, but can not solve the problem fundamentally, and has the problems of large side effects and not obvious curative effect. The cough syrup has the advantages of easily available raw materials, rapidness in absorption, low cost, and rapidness in taking effect, and is easily accepted by people.
Owner:HUBEI TUNGSHUN PHARMA

Snow pear cough-relieving syrup and preparation method

The invention relates to a snow pear cough-relieving syrup and a preparation method, which belongs to the composite traditional Chinese medicine technology field. The snow pear cough-relieving syrup solves the problem that the current drugs and transfusion has poor therapeutic effect for rapidly treating cough. The snow pear cough-relieving syrup comprises the following raw materials: 5-15 parts of balloonflower root, 5-15 parts of bitter apricot kernel (fried), 5-15 parts of radix peucedani, 10-25 parts of radix asteris (roasted), 10-25 parts of Common Coltsfoot Flower, 10-30 parts of loquatleaf and 100-300 parts of pear paste. The method comprises the following steps: taking white pear or pyrus ussuriensis, squeezing to obtain the juice, decompressing and concentrating to obtain a stiff paste, employing an ethanol cold leaching method on the other medicinal materials for extracting an effective ingredient, preparing to obtain the stiff paste, adding 700g of cane sugar and other auxiliary materials to obtain the syrup. The snow pear cough-relieving syrup has the advantages of good effect for cough-relieving, good mouthfeel, accurate administration amount and difficult contamination. The snow pear cough-relieving syrup is used for moistening lung, relieving cough and reducing phlegm, and has obvious effect and good security for treating cough, expectoration and bronchitis.
Owner:HUBEI WUDANG JINDING PHARMA

Detection method for cough syrup

The invention provides a detection method for cough syrup and relates to a detection method for a traditional Chinese medicine preparation. The detection method is adopted for monitoring the illegal manufacturer which invests few or no corresponding medicinal materials and even mixes the forbidden medicinal materials, which causes the result that the medicine cannot achieve the proper clinical effect. The prescription of the cough syrup provided by the invention includes ephedra, semen armeniacae amarae, gypsum and liquorice (roasted). Through the thin-layer identification for ephedra, ephedra root and ephedra alkali A, thin-layer identification for semen armeniacae amarae, thin-layer identification for liquorice and content determination of ephedrine hydrochloride in the cough syrup, components and component contents of traditional Chinese medicine cough syrup can be effectively detected, necessary medicinal materials including ephedra, semen armeniacae amarae and liquorice contained in the medicine can be ensured and meanwhile, mixing of the forbidden medicine ingredient of ephedra roots is prevented; the method is scientific and reasonable as well as practicable; the medicine is more safe and effective, so that the clinical effect of the particle preparation can be ensured and the benefit of the patient is protected.
Owner:SICHUAN FENGCHUN PHARMA

Cough syrup for children and preparation method thereof

The invention discloses cough syrup for children and a preparation method thereof. The cough syrup for children is prepared from, by weight, 600-700 parts of saccharose, 100-200 parts of honey, 40-60 parts of licorice roots, 45-55 parts of loquat leaves, 30-50 parts of gypsum fibrosum, 20-40 parts of rhizoma menispermi, 20-30 parts of platycodon grandiflorum, 20-30 parts of honeysuckle flowers, 20-30 parts of fritillaria cirrhosa, 20-30 parts of radix scutellariae, 15-25 parts of orange peel tincture, 15-25 parts of herba ephedra, 10-15 parts of lalang grass rhizome, 8-12 parts of the root of kudzu vine, 8-12 parts of radix ophiopogonis, 8-12 parts of ammonium chloride, 2.5-3.5 parts of sodium benzoate, 1-3 parts of lemon essence, 1-2 parts of lumbricus and 0.03-0.05 part of menthol. By adopting the theory of traditional Chinese medicine, the syrup is artificially synthesized from Chinese medical extract, is capable of clearing heat and moistening lung, ventilating lung and dispelling cold, preventing phlegm from forming and stopping coughing, and tonifying spleen and tonifying qi, is used for treating a cough and bronchitis caused by a cold, is good in effect and high in efficiency, has no toxic or side effect on the human body and can nourish the stomach. The cough syrup is reasonable in preparation, easy to prepare, free of side effects, safe, reliable, stable in quality, convenient to take, free of resistance of children and capable of being fed to children easily.
Owner:HANGZHOU HUAWEI PHARMA LLC

Detection method for phlegm eliminating and asthma relieving cough syrup

The invention belongs to the technical field of Chinese patent medicaments, and relates to a quality control method for phlegm eliminating and asthma relieving cough syrup prepared from raw materials which are Chinese medicinal plants. In quality standards, Dahurian rhododendron leaf serves as a reference medicinal plant and baicalin serves as a reference substance, and whether the phlegm eliminating and asthma relieving cough syrup or Changcheng Zhikechuan Tangjiang contains Dahurian rhododendron leaf and baicalin components or not is detected by a thin layer chromatography. In the method, quack medicaments and inferior medicaments can be more accurately inspected and safety in use is improved; high performance liquid chromatography for detecting the baicalin content of the phlegm eliminating and asthma relieving cough syrup, the quantitative index of baicalin content of not less than 0.6 microgram of every milliliter of phlegm eliminating and asthma relieving cough syrup, and the inspection method improve the quality standard controllability of the phlegm eliminating and asthma relieving cough syrup, further ensure the inherent quality and curative effect of the product and relatively more perfect the quality standards; and modified quality standards enhance quality control over medicaments.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Cough syrup with effects of moistening lungs and stopping cough

The invention discloses a cough syrup with effects of moistening the lungs and stopping cough, which comprises the following raw materials in percentage by weight: 10-20% of radix scutellariae, 5-15% of angelicae sinensis, 2-5% of acorus gramineus, 3-4% of rock candy, 10-15% of pear, 8-12% of chrysanthemum, 20-25% of eriobotrya japonica leaf, 0.2-0.35% of glucose, 0.3-0.46% of an additive and the rest of water. The cough syrup has the benefits that the formula is scientific, reasonable, practical and feasible, the major ingredients in the formulation (eriobotrya japonica leaf, rock candy, pear, radix scutellariae, angelicae sinensis and acorus gramineus) all have the effects of effectively stopping cough and moistening the lungs, and the customer demand is satisfied.
Owner:张娟

Quality control method for phlegm eliminating and asthma relieving cough syrup

The invention belongs to the technical field of Chinese patent medicaments, and relates to a quality control method for phlegm eliminating and asthma relieving cough syrup prepared from raw materials which are Chinese medicinal plants. In quality standards, Dahurian rhododendron leaf serves as a reference medicinal plant and baicalin serves as a reference substance, and whether the phlegm eliminating and asthma relieving cough syrup or Changcheng Zhikechuan Tangjiang contains Dahurian rhododendron leaf and baicalin components or not is detected by a thin layer chromatography. In the method, quack medicaments and inferior medicaments can be more accurately inspected and safety in use is improved; high performance liquid chromatography for detecting the baicalin content of the phlegm eliminating and asthma relieving cough syrup, the quantitative index of baicalin content of not less than 0.6 microgram of every milliliter of phlegm eliminating and asthma relieving cough syrup, and the inspection method improve the quality standard controllability of the phlegm eliminating and asthma relieving cough syrup, further ensure the inherent quality and curative effect of the product and relatively more perfect the quality standards; and modified quality standards enhance quality control over medicaments.
Owner:津药达仁堂集团股份有限公司乐仁堂制药厂

Snake gall bulbus fritilariae cough syrup and preparation method thereof

The invention relates to snake gall bulbus fritilariae cough syrup and a preparation method thereof, and belongs to the technical field of Chinese herbal medicines. According to the snake gall bulbus fritilariae cough syrup and the preparation method thereof, from a motherland medicine treasure house, cortex mori radicis which can clearing lung heat and relieve a cough and asthma is selected to serve as a monarch drug, cortex lycii radicis, snake bile, bulbus fritillariae cirrhosae and scutellaria baicalensis which can clear heat, moisten the lungs, dissipate phlegm and relieve the cough are selected to serve as ministerial drugs, rhizoma phragmitis which can clear heat, purge fire and promote secretion of saliva or the body fluid and pericarpium citri reticulatae which can strengthen the spleens, regulate qi and dissipate phlegm are selected to serve as adjuvant drugs, honey-fried licorice roots which can nourish the stomach, regulate the middle warmer, relieve the cough, dissipate phlegm and coordinate all the medicines are selected to serve as conductant drugs; the whole formula jointly achieves the effects of clearing heat, moistening the lungs, dissipating phlegm and relieving the cough. The snake gall bulbus fritilariae cough syrup is suitable for the symptoms of excessive phlegm and cough caused by respiratory tract tracheal diseases, has the advantages of being reasonable in cost, few in toxic and side effects, convenient to take, rapid in curative effect and capable of eradicating the disease pain and solves the problems that existing cough relieving drugs mostly have certain side effects, can only relieve the symptoms, but cannot fundamentally dispel the disease pain. The snake gall bulbus fritilariae cough syrup can be produced in batches, is wide in suitable crowds and has the extremely high promotional value.
Owner:HUBEI TUNGSHUN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products